Sentences with phrase «cells in lab dishes»

They grew pancreatic cancer cells in lab dishes and fed them both glucose and fructose.

Zhang has been using a different approach — studying diseased human cells in lab dishes.

Their study, published in the ACS journal Chemical Research in Toxicology, found that triclosan, as well as another commercial substance called octylphenol, promoted the growth of human breast cancer cells in lab dishes and breast cancer tumors in mice.

Building on previous work from Yuan's lab showing that the activity of RIPK1 could be blocked by a chemical called necrostatin - 1, the research team tested how ALS cells in lab dishes would respond to the same treatment.

Chemical biology and drug discovery usually depend on screens of cells in lab dishes, for example.

After 381 days, this cow's antibodies prevented 96 percent of the 117 HIV types from infecting cells in a lab dish.

When the researchers applied some of these cultures to mouse colon cells in the lab dish, the cells were stimulated to release PYY hormone.

In subsequent experiments, the Harvard scientists found that p53 mutant cells outperformed and outcompeted non-mutant cells in the lab dish.

«The blood - brain barrier forms pretty early in gestation, so the thyroid hormone, even from the mother, is probably not getting through the barrier and into the brain, likely leading to developmental deficits,» says Shusta, whose group was among the first to develop blood - brain barriers from patient - derived stem cells in the lab dish.

Both teams successfully used these to reprogramme skin cells in a lab dish into cells resembling embryonic stem cells, which have the ability to turn into any tissue of the human body.

Wang's team discovered that if human lung cancer cells in a lab dish in the presence of the receptor were treated with BCX, they migrated less than untreated ones.

Not exact matches

But the next big question was whether these cells could home in on tumors in lab dishes, and in animals, like neural stem cells.

Now one team reports in ACS» journal Environmental Science & Technology that small amounts of house dust containing many of these compounds can spur fat cells to accumulate more triglycerides, or fat, in a lab dish.

House dust may contain compounds that can spur fat cells to accumulate more triglycerides, or fat, in a lab dish.

WASHINGTON — Tiny orbs of brain cells swirling in lab dishes may offer scientists a better way to study the complexities of the human brain.

In lab dish experiments, exo - AAV successfully penetrated 50 - 60 percent of hair cells, the researchers observed.

In lab dishes, the blast cells formed tissues that resembled blood - forming stem cells as well as blood vessels, the group found.

In experiments in human cells grown in a lab dish, the researchers showed that they could accurately label mRNA molecules and determine how frequently they are being translateIn experiments in human cells grown in a lab dish, the researchers showed that they could accurately label mRNA molecules and determine how frequently they are being translatein human cells grown in a lab dish, the researchers showed that they could accurately label mRNA molecules and determine how frequently they are being translatein a lab dish, the researchers showed that they could accurately label mRNA molecules and determine how frequently they are being translated.

So far, researchers have mostly turned on genes with CRISPRa in cells growing in lab dishes, says Charles Gersbach, a biomedical engineer at Duke University not involved in the new study.

That would be getting close to the number of cells in a mouse brain,» raising the distant prospect of a human brain organoid with cognitive and even emotional capacities, all while sitting in a lab dish.

Already, researchers have used CRISPR / Cas9 to edit genes in human cells grown in lab dishes, monkeys (SN: 3/8/14, p. 7), dogs (SN: 11/28/15, p. 16), mice and pigs (SN: 11/14/15, p. 6), yeast, fruit flies, the worm Caenorhabditis elegans, zebrafish, tobacco and rice.

That allowed tumor cells to survive gemcitabine treatment in lab dishes and mouse studies, Leore Geller of the Weizmann Institute of Science in Rehovot, Israel, and colleagues discovered.

Zheng, together with Leah Boyer, then a researcher in Gage's lab and now director of Salk's Stem Cell Core, generated diseased neurons by taking skin cells from patients with Leigh syndrome, reprogramming them into stem cells in culture and then coaxing them to develop into brain cells in a dish.

In many important respects they behave just like other human cells, and they live indefinitely in lab dishesIn many important respects they behave just like other human cells, and they live indefinitely in lab dishesin lab dishes.)

Mouse brain nerve cells (green) making a disease - causing version of the tau protein were grown in lab dishes with supporting brain cells called glia.

The disease model, described in a new study by a UC San Francisco - led team, involves taking skin cells from patients with the bone disease, reprogramming them in a lab dish to their embryonic state, and deriving stem cells from them.

Xu and colleagues grew S. gallolyticus in lab dishes with several different types of human cells.

Glioblastomas in lab dishes and mouse brains are fakes, little Potemkin villages that everyone thought were faithful replicas of human glioblastomas but which, lacking tumor stem cells, were nothing of the kind.

According to his unpublished findings, when he puts glioblastoma cells from patients into lab dishes with brain organoids, the cells attach to the surface of the organoids, burrow into them, and within 24 to 48 hours grow into a mass that eventually «looks exactly like what happened in the patient's own brain,» Fine said.

But when dermal papilla cells from humans are put into dishes in the lab, they lose their ability to induce the formation of new follicles.

A technician in a Kyoto University lab uses an electronic pipette to transfer cells into petri dishes before they are placed into an incubator.

At the time, culturing stem cells was notoriously hard, but after combing through previous lab experiments, another postdoc in Clevers's lab, Toshiro Sato, concocted a mix of growth factors that coaxed the gut stem cells to replicate in a dish.

This capability allowed the researchers to maneuver the nanospears in a lab dish to modify brain cancer cells so that they expressed a green fluorescent protein.

Part of the issue was settled when Cecilia Riquelme, a postdoc in Leinwand's lab, drew blood from recently fed pythons and applied it to a dish of living rat heart cells.

In a paper published Sept. 21 in Cell, Harvard Medical School genetics professor Olivier Pourquié — whose lab discovered the segmentation clock 20 years ago — and colleagues report that they used mouse cells to reconstitute a stable version of this clockwork for the first time in a petri dish, leading to several new discoveries about where the clock is located, what makes it tick and how the vertebral column takes shapIn a paper published Sept. 21 in Cell, Harvard Medical School genetics professor Olivier Pourquié — whose lab discovered the segmentation clock 20 years ago — and colleagues report that they used mouse cells to reconstitute a stable version of this clockwork for the first time in a petri dish, leading to several new discoveries about where the clock is located, what makes it tick and how the vertebral column takes shapin Cell, Harvard Medical School genetics professor Olivier Pourquié — whose lab discovered the segmentation clock 20 years ago — and colleagues report that they used mouse cells to reconstitute a stable version of this clockwork for the first time in a petri dish, leading to several new discoveries about where the clock is located, what makes it tick and how the vertebral column takes shapin a petri dish, leading to several new discoveries about where the clock is located, what makes it tick and how the vertebral column takes shape.

Researchers took cells from leaves of the most productive trees and grew them in a lab dish to produce cloned seedlings.

So instead of studying the whole animals, he began isolating single nerve cells from the mole rats and investigating them in lab dishes to track the molecular basis of the rodent's pain insensitivity.

The traditional technique for identifying promising nanoparticles examines how the particles enter living cells kept in lab dishes.

Researchers realized that they could cut open the top of the trunks of their highest - yielding trees, extract stem cells and grow up clones by the thousands in lab dishes.

The researchers isolated tumor cells from patients and grew them to reproduce small tumors in the lab dish.

And because CRISPR works so well in cells growing in a lab dish, some tests can forgo using animals altogether.

However, most of these efforts failed, even though the antibody - IL - 2 combination usually works very well against cancer cells grown in a lab dish.

Traditionally, cell culture in the lab has been done in petri dishes and on other flat surfaces.

The patient, already in a wheelchair, visited the lab and watched in amazement as his own muscle cells beat in a culture dish after corrective editing.

In 2013, the lab of Peter Walter, a biochemist at the University of California, San Francisco (UCSF), discovered a compound — called ISRIB — that blocked the stress response in human cells in a disIn 2013, the lab of Peter Walter, a biochemist at the University of California, San Francisco (UCSF), discovered a compound — called ISRIB — that blocked the stress response in human cells in a disin human cells in a disin a dish.

A key difference, however, is that Dolly's donor cell came from adult udder cells growing in lab dishes (see ScienceNOW, 24 February), while the donor cells used to create the monkey clones came from early embryos.

But when physiologist H. Lee Sweeney of the University of Pennsylvania School of Medicine in Philadelphia and his colleagues put this faulty gene into embryonic quail muscle cells growing in lab dishes, the cells made a shortened version of the protein and incorporated it into their contractile machinery.

In this case, the researchers used samples from juveniles and adults with Fragile X syndrome and induced the cells to become neurons in a lab disIn this case, the researchers used samples from juveniles and adults with Fragile X syndrome and induced the cells to become neurons in a lab disin a lab dish.

Researchers have previously demonstrated that yeast, fruit fly cells and some types of human cells grown in lab dishes divvy up proteins unequally.

While testing that idea, the researchers noticed something peculiar about cancerous cells that had been removed from leukemia patients and were growing in lab dishes.