Sentences with phrase «cells in lab tests»

But this humble substance has also been studied for its biological activity against more serious matters like cancer cells in lab tests.

A COMPOUND that slows the proliferation of triple - negative breast cancer cells in lab tests could lead to the first drugs to target this aggressive type of tumour.

Not exact matches

Researchers at Tufts Medical School noticed that cancer cells being grown in the lab multiplied more quickly in polyester test tubes than in glass.

The audience roars with laughter as Polish tells how he initiated select new members into the cell biology lab he worked in after college with strategically placed miniature dry - ice bombs fabricated from plastic Eppendorf test tubes.

Each of the four compounds was then tested in the lab to see how it would affect a line of prostate cancer cells relatively sensitive to the chemotherapeutic Paclitaxel, commonly used to treat prostate cancer patients.

One lab test showed a single cell moving a distance three times its diameter and joining with a small cancerous cluster in just four hours.

In lab tests, they show that one such particle can be produced in plants and it ferries small molecules to cancer cellIn lab tests, they show that one such particle can be produced in plants and it ferries small molecules to cancer cellin plants and it ferries small molecules to cancer cells.

In addition, the substance used to stick cells together (ViaGlue), will provide researchers with tools to create and test 3D in vitro cardiac tissue in their own labs to study heart disease and issues with transplantatioIn addition, the substance used to stick cells together (ViaGlue), will provide researchers with tools to create and test 3D in vitro cardiac tissue in their own labs to study heart disease and issues with transplantatioin vitro cardiac tissue in their own labs to study heart disease and issues with transplantatioin their own labs to study heart disease and issues with transplantation.

Bloch's colleagues at the National Institute of Environmental Health Sciences tested the oils in gene expression studies on lab - grown human breast cancer cells and found that they could mimic estrogens, the primary female sex hormones, and inhibit androgens, the primary male sex hormones.

Next, the team tested the GD2 CAR - T cells in mice whose brainstem was implanted with human DIPG tumors, an experimental system that Monje's lab pioneered.

Lab testing showed that the plant - made virus particles, which naturally bind to receptors on cancer cells, were taken in by human breast cancer cells.

In its test in its Danbury lab, the company plans to mix carbon dioxide, air and nitrogen to simulate coal plant emissions and then shoot those gases into a fuel cell stacIn its test in its Danbury lab, the company plans to mix carbon dioxide, air and nitrogen to simulate coal plant emissions and then shoot those gases into a fuel cell stacin its Danbury lab, the company plans to mix carbon dioxide, air and nitrogen to simulate coal plant emissions and then shoot those gases into a fuel cell stack.

So far Kajander and his colleagues have found the nanobacteria in cattle blood, in 80 % of samples of commercial cow serum in which mammalian cells are grown in the lab, and in the blood of nearly 6 % of more than 1000 Finnish adults tested.

In studies with human fibroblasts that make up connective tissue, Boger's team tested whether NOD1 activity could affect CMV replication in cultures of cells grown in the laIn studies with human fibroblasts that make up connective tissue, Boger's team tested whether NOD1 activity could affect CMV replication in cultures of cells grown in the lain cultures of cells grown in the lain the lab.

Tissue engineers have been unable to grow epidermis with the functional barrier needed for drug testing, and have been further limited in producing an in vitro (lab) model for large - scale drug screening by the number of cells that can be grown from a single skin biopsy sample.

First, the destabilizing effects of VX - 770 on the corrected CFTR protein might be less robust in the human body than were the effects seen in lab tests using human lung cells.

In lab tests, the CpG - antigen package, at 300 nanometers in size, was absorbed 90 percent of the time by immune cells, the UI - led team reportIn lab tests, the CpG - antigen package, at 300 nanometers in size, was absorbed 90 percent of the time by immune cells, the UI - led team reportin size, was absorbed 90 percent of the time by immune cells, the UI - led team reports.

We hope this leads to the ability to design, study and test new therapies for every patient on their own cells in the lab, leading to new treatments and breakthroughs in personalized medicine for individuals with a variety of lung diseases, including cystic fibrosis,» explained lead author Katherine McCauley, a PhD student at BUSM.

To test their theory, Xiaoli Guo, a post-doctoral researcher in Mitchum's lab and first author of the study, synthesized the CLE - B nematode peptide and applied it to the vascular cells of Arabidopsis, a model plant system used in plant research.

Though Li's adhesive has been tested only in human cell cultures and in lab animals, another bio-inspired glue has made its way into human trials.

They tested these drugs one at a time for lethal interaction with 112 different tumor - suppressor gene mutations in human cancer cells growing in the lab.

In lab tests the refurbished cells cured the disease in mice and in human blooIn lab tests the refurbished cells cured the disease in mice and in human blooin mice and in human blooin human blood.

The team reports that ELP hydrogel can be digested overtime by naturally - occurring enzymes and does not appear to have toxic effects when tested with living cells in the lab.

Some basic research findings are being translated into new treatments, and with the discovery of induced pluripotent stem cells in 2006, the field has seen a step - change in biological understanding that will affect the way new drugs are identified and tested and, potentially, the way cells can be generated in the lab.

Building on previous work from Yuan's lab showing that the activity of RIPK1 could be blocked by a chemical called necrostatin - 1, the research team tested how ALS cells in lab dishes would respond to the same treatment.

Synthetic biology, which involves designing and building genetic constructs and testing them in living cells, requires wet lab skills.

«In lab tests, the antimicrobial ingredient triclosan spurs growth of breast cancer cells.»

Those tests will answer basic questions about changes in cells and genes; they are not the elaborate, years - long studies exposing lab animals or examining humans that can answer most important health questions.

In a series of lab tests, they found that cells lacking the enzyme are severely inhibited in their ability to movIn a series of lab tests, they found that cells lacking the enzyme are severely inhibited in their ability to movin their ability to move.

When the team tested the drug on cells grown in the lab, they found that it killed blood vessel cells and prevented growth of new blood vessels.

And because CRISPR works so well in cells growing in a lab dish, some tests can forgo using animals altogether.

Traditionally, researchers then disable or «knock out» the gene in lab - grown cells or animals to test their hypothesis, a time - consuming and laborious process.

Yongyou Zhang, PhD, a Case Western Reserve research associate in Markowitz's lab and a lead author on the study, developed a test where cells glowed when 15 - PGDH levels changed.

The existence of cancer stem cells has already been reported in a number of human cancers, explains Professor Jacobsen, but previous findings have remained controversial since the lab tests used to establish the identity of cancer stem cells have been shown to be unreliable and, in any case, do not reflect the «real situation» in an intact tumour in a patient.

Labs can test their proficiency at carrying out the polymerase chain reaction (PCR), a technique that generates usable quantities of DNA from cells in a tiny sample of blood or semen.

The Simon lab is now working on testing the effects of the chimera on human liver cells and in mouse livers, to further elucidate its role in the disease.

Scientists have suggested that such embryonic stem cells could be used for learning about genetic diseases, testing new drugs on cells grown in the lab, or growing healthy cells for therapeutic transplantation.

While testing that idea, the researchers noticed something peculiar about cancerous cells that had been removed from leukemia patients and were growing in lab dishes.

When current methods for generating naïve stem cells in the lab were judged using the three tests, each fell short of mimicking the naïve embryonic cells in different ways.

The Norwegian analysis was done after researchers at Harvard University found these effects of the medicines in animal tests and in experiments with brain cells in the lab.

They geared their experimental design towards conducting direct measurements in space: From thawing the test cells to the measurements themselves, ESA astronaut Samantha Cristoforetti performed all the operations directly in the lab on the ISS.

The team plans to test the approach in a clinical trial in which chemotherapy drug selection for each person will be guided by testing balls of their tumour cells in the lab.

Lab tests showed that this drug works as well as expected in cells (Cell, doi.org/chz8).

«One of the unique features of µSCALE is that it allows researchers to rapidly isolate a single desired cell from hundreds of thousands of other cells,» said Bob Chen, a doctoral student in Cochran's lab who wrote the software to examine and detect signs of interesting protein activity within the test tubes.

The work was performed in collaboration with Arjan Narbad's lab at the Institute of Food Research in Norwich, UK, who tested how engineering mutations in the endolysins affected their ability to tear down the bacterial cell wall.

«This discovery reverses food allergies in mice, and we have many people with allergies volunteering their own cells for us to use in lab testing to move this research forward,» said professor John Gordon, lead scientist behind the discovery just published in the current issue of the Journal of Allergy and Clinical Immunology.

They tested 120 neural stem cell lines in the lab for stability and robustness and in animals for the capacity to engraft with minimal immune rejection.

To identify promising compounds, the team grew human nerve cells in the lab and tested whether more than 1100 medications, vitamins, dietary supplements, and other molecules altered their output of α - synuclein.

The Zeng lab is making great progress on developing a stem cell - derived treatment for Parkinson's disease for testing in humans.

If the marriage of stem cells and CRISPR follows a similar path, it might not be long before pigs have enough Homo sapiens in them not only to grow human hearts, lungs, livers, and kidneys for transplant but also to model human diseases more closely than current lab animals do and to test experimental drugs.