Sentences with phrase «cells in laboratory studies»

The artemisinin herb has been shown to kill both human and canine cancer cells in laboratory studies.

One of them, naringenin, has been shown to inhibit growth of breast cancer and other cancer cells in laboratory studies.

Gold nanotubes engineered to a specified length, modified surfaces, and to have other desirable characteristics showed expected abilities to enter tumor cells in laboratory studies, and to distribute to tissues within live mice as intended.

The researchers then tested the capacity of the modified cells to kill human multiple myeloma cells in laboratory studies and an animal model.

Isoflavones have been shown to slow the growth of breast cancer cells in laboratory studies, and epidemiological analyses in East Asian women with breast cancer found links between higher isoflavone intake and reduced mortality.

Not exact matches

To create the effect of tobacco smoke on cells, Vaz, Baylin and their colleagues began their studies with human bronchial cells, which line the airways of the lungs, and grew them in a laboratory.

Immunophenotyping — a laboratory procedure used to study the proteins expressed by cells — is very commonly used in basic science research as well as in laboratory diagnostic testing.

According to the latest studies from the fly laboratory of California Institute of Technology (Caltech) biologist David Anderson, male Drosophilae, commonly known as fruit flies, fight more than their female counterparts because they have special cells in their brains that promote fighting.

Research for the study was conducted by first co-authors Dr. Ranit Kedmi and Nuphar Veiga and colleagues at Prof. Peer's TAU Laboratory, in collaboration with Prof. Itai Benhar of TAU's School of Molecular Cell Biology and Biotechnology, Dr. Michael Harlev of TAU's Veterinary Service Center, Dr. Mark Belkhe of Integrated DNA Technologies (IDT) and Prof. Judy Lieberman of Boston Chidren's Hospital and Harvard Medical School.

Adding stem cells from human bone marrow to a broken diabetic bone enhances the repair process, increasing the strength of the newly formed bone, according to a laboratory - based study presented at the European Congress of Endocrinology in Dublin.

The researchers added human bone marrow stem cells from a non-diabetic donor to a bone fracture in laboratory pre-clinical studies.

According to Izpisúa Belmonte, who is also a professor at the gene expression laboratories of the Salk Institute for Biological Studies in San Diego, California, CMRB aims to become «a research centre of excellence in south Europe in the line of world - recognized institutions such as the Salk or the Whitehead institutes, where both pre - and postdoctoral researchers receive multidisciplinary training of the highest quality» in stem cell biology and cell regeneration.

To find out, John O'Neill, a biologist at the Medical Research Council's Laboratory of Molecular Biology in Cambridge, U.K., and his team studied skin cells known as fibroblasts, which are essential for wound healing.

Now, in a new study using laboratory - grown cells and mice, Johns Hopkins scientists report that a method they used to track metabolic pathways heavily favored by cancer cells provides scientific evidence for combining anti-cancer drugs, including one in a nanoparticle format developed at Johns Hopkins, that specifically target those pathways.

By studying infected cells grown in a laboratory, the team found that a large number of CMV's genes help it hide from the immune system by allowing it to destroy many of the proteins produced by the body during virus infection and preventing them from activating immune cells to destroy the virus.

The team also compared the animals» responses to the therapy's effects in laboratory cell samples and found that in vitro studies did not predict how well the viral therapy and immune response would fight tumor cells in vivo.

Cook, who also serves as director of operations and research at MU Health Care's Mizzou BioJointSM Center and director of the Thompson Laboratory for Regenerative Orthopaedics, led a pre-clinical study earlier in 2017 that showed BMC provides cells to infiltrate the donor bone and release proteins important to bone healing.

Cell lines are the workhorses of biology, routinely stocked and studied in every laboratory to understand cellular pathways, receptors, targets, hormones, and all aspects of normal and malignant physiology.

Spearheaded by first author Christopher McNair, PhD, a graduate student in the laboratory of Dr. Knudsen, the study undertook an extensive analysis of tumor samples and cell - free DNA samples from patients with advanced, lethal - stage prostate cancer.

«It's taken years of trial and error, making educated guesses and taking baby steps to finally produce functioning human muscle from pluripotent stem cells,» said Lingjun Rao, a postdoctoral researcher in Bursac's laboratory and first author of the study.

According to the researcher, further studies are warranted to confirm responses in primary cells and to reveal whether Rho - kinase inhibition stimuli can be used to manufacture a better cartilage - type of tissue in laboratory.

«As a biologist, I needed simple yet tunable cell - culture gels that would give me a defined system to study metabolites in the laboratory.

Building on the newly - published pilot study, the team will conduct experiments using a windtunnel which measures the behaviour of mosquitoes towards odours and electrodes which track the response of individual odour - detecting cells from within the antenna of the mosquito in specially - designed secure laboratories at the School to measure the responses of malaria - infected Anopheles gambiae s.s. females to human odours.

Joseph Berry, senior research scientist at the National Renewable Energy Laboratory, who studies solar cells but was not involved in the research, said the research project is interesting because the device scales well and targets a specific part of the solar spectrum.

While most research studies begin in test tubes, cells grown in the laboratory and animal models before moving to humans, the opposite is true here.

«Our study shows that protein production in neurons is one of the major utilizers of energy and that neurons of Leigh syndrome degenerate because they can't sustain a high enough level of energy,» says Tony Hunter, the Renato Dulbecco Chair and American Cancer Society Professor in Salk's Molecular and Cell Biology Laboratory, who led the research.

Health: Combined Optical and Magnetic Resonance Microscope - «Studying cells in real time» Dr. Robert Wind, Scientist at Pacific Northwest National Laboratory in Richland, WA helped develop a combined microscope that can study live cells at the same time with two completely different microscopic techniques.

These early studies were in laboratory - cultured cells.

While blood cells live in a convenient, easily studied liquid, most other cell types have been harder to analyze in the laboratory.

Complex phenomena — which we have so far only been able to study in live animals - can now be investigated in simple laboratory experiments using cultivated cells,» says postdoc Hans Christian Cederberg Helms from the Department of Pharmacy.

«Notably, we also observed a small increase in blood histamine levels and a slight release of tryptase from mast cells in the skin of unaffected individuals exposed to vibration,» said Hirsh Komarow, M.D., of NIAID's Laboratory of Allergic Diseases, the senior author of the study.

In laboratory studies reported in the Proceedings of the National Academy of Sciences (PNAS), the researchers found that these «neutralizing» antibodies prevented a key part of the virus, known as MERS CoV, from attaching to protein receptors that allow the virus to infect human cellIn laboratory studies reported in the Proceedings of the National Academy of Sciences (PNAS), the researchers found that these «neutralizing» antibodies prevented a key part of the virus, known as MERS CoV, from attaching to protein receptors that allow the virus to infect human cellin the Proceedings of the National Academy of Sciences (PNAS), the researchers found that these «neutralizing» antibodies prevented a key part of the virus, known as MERS CoV, from attaching to protein receptors that allow the virus to infect human cells.

After completing her graduate studies in 2006, she joined the laboratory of Dr. Craig B. Thompson at the University of Pennsylvania for postdoctoral work focusing on cancer cell metabolism.

In laboratory studies, daratumumab caused the targeted killing of CD38 - carrying tumor cells by several distinct and potent mechanisms, including some that involve the immune system.

In their new study, they adapted DNA - PAINT technology to microscopes that are widespread among cell biology laboratories, called confocal microscopes, and that are used by researchers to image whole cells and thicker tissues at lower resolution.

By now, European astronauts had hoped to be established in their space laboratory called Columbus, where they would be melting and solidifying conductive metals, studying microgravity effects on single - celled organisms, investigating human balance disorders, and carrying out dozens of other experiments.

A study led by researchers from Lawrence Berkeley National Laboratory has found for the first time that thirdhand smoke — the noxious residue that clings to virtually all surfaces long after the secondhand smoke from a cigarette has cleared out — causes significant genetic damage in human cells.

Their approach is to combine the study of cells isolated from TB - infected patients with micro-engineering in 3D in the laboratory to investigate how TB damages the lungs.

The first study of the development of such «germ cells» from humans could help scientists to learn how to create them in the laboratory instead.

«We found that fibrinogen stops adult stem cells from transforming into the mature cells that produce myelin,» explained first author of the study Mark Petersen, MD, a visiting scientist in Akassoglou's laboratory and an assistant adjunct professor of pediatrics at UCSF.

They then grew these into organoids — 3D «mini-guts» — in the laboratory to amplify the single cells so they could be studied.

«For example, we found that highly aggressive ovarian cancer cells are glutamine - dependent, and in our laboratory studies, we showed that depriving such cells of external sources of glutamine — as some experimental drugs do — was an effective way to kill late - stage cells.

«Activation of these cell receptors appear to prevent brain cells from cleaning out the trash — the toxic buildup of proteins, such as alpha - synuclein, tau and amyloid, common in neurodegenerative diseases,» says the study's senior author, neurologist Charbel Moussa, MBBS, PhD, director of Georgetown's Laboratory for Dementia and Parkinsonism, and scientific and clinical research director of the GUMC Translational Neurotherapeutics Program.

In a new study published in Science, the laboratory of Sebastian Jessberger, professor in the Brain Research Institute of the University of Zurich, has shown for the first time the process by which neural stem cells divide and newborn neurons integrate in the adult mouse hippocampuIn a new study published in Science, the laboratory of Sebastian Jessberger, professor in the Brain Research Institute of the University of Zurich, has shown for the first time the process by which neural stem cells divide and newborn neurons integrate in the adult mouse hippocampuin Science, the laboratory of Sebastian Jessberger, professor in the Brain Research Institute of the University of Zurich, has shown for the first time the process by which neural stem cells divide and newborn neurons integrate in the adult mouse hippocampuin the Brain Research Institute of the University of Zurich, has shown for the first time the process by which neural stem cells divide and newborn neurons integrate in the adult mouse hippocampuin the adult mouse hippocampus.

«Our study reveals that a stable microvasculature constitutes a dormant niche, whereas a sprouting neovasculature sparks micrometastatic outgrowth,» says cell biologist Mina Bissell, in whose laboratory this work was done.

Apart from a few studies in mouse models and in cell lines, there is no laboratory evidence that synthetic phosphoethanolamine works as a cancer drug.

Bruce Buchholz of the Lawrence Livermore National Laboratory used cellular markers for a study in which he concluded that we're more or less stuck with the number of fat cells we have at about age 20.

Biologist Michael Wigler of Cold Spring Harbor Laboratory, who led the study, started out studying genes in cancer cells but soon realized he was seeing unexpected patterns in the healthy cells he examined for reference.

The laboratory of Marcos Malumbres, who is head of the Spanish National Cancer Research Centre's (CNIO) Cell Division & Cancer Group, working alongside Isabel Fariñas» team from the University of Valencia, shows, in a study published today in the journal Nature Communications, how in mice the elimination of the Cdh1 protein — a sub-unit of the APC / C complex, involved in the control of cell division — prevents cellular proliferation of rapidly dividing ceCell Division & Cancer Group, working alongside Isabel Fariñas» team from the University of Valencia, shows, in a study published today in the journal Nature Communications, how in mice the elimination of the Cdh1 protein — a sub-unit of the APC / C complex, involved in the control of cell division — prevents cellular proliferation of rapidly dividing cecell division — prevents cellular proliferation of rapidly dividing cells.

«This lets us keep age - related signatures in the cells so that we can more easily study the effects of aging on the brain,» says Rusty Gage, a professor in the Salk Institute's Laboratory of Genetics and senior author of the paper, published October 8, 2015 in Cell Stem Cell.