Sentences with phrase «cells in laboratory tests»

One of these, UJ3, is as effective as the industry - standard drug Cisplatin in killing cancer cells in laboratory tests done on human esophageal cancer, breast cancer and melanoma.

Not exact matches

Researchers at the European Union Reference Laboratory for alternatives to animal testing developed five different tests that use human blood cells to detect contaminants in drugs that cause a potentially dangerous fever response.

Immunophenotyping — a laboratory procedure used to study the proteins expressed by cells — is very commonly used in basic science research as well as in laboratory diagnostic testing.

The scientists then tested three new mTOR inhibitors currently under development (pp242, AZD8055 and INK128) in combination with the chemotherapies AraC, Etoposide and Cisplatin to see how they affected laboratory lines of leukemia cells and mouse models of the disease.

Results suggest that while isotretinoin was associated with a change in the average value of some laboratory tests (white blood cell count and hepatic and lipid panels), the average change across a patient group did not meet the criteria for high - risk and the proportion of patients with laboratory abnormalities was low, the authors report.

While most research studies begin in test tubes, cells grown in the laboratory and animal models before moving to humans, the opposite is true here.

«Despite the fact that the literature describes only correlation between verbal memory tests and hippocampal cell densities in patients with left hippocampal sclerosis, we found a correlation between right hippocampal cell densities and performance on visual memory tests, including both immediate and delayed recall,» says authors Sandra Mara Comper and Anaclara Prada Jardim, students in the laboratory of Dr. Elza Marcia Yacubian at the Federal University of São Paulo.

Although the gene / cell therapy strategy was highly successful in laboratory mice, the authors stressed that additional research and testing are needed before the therapy could be tested in humans.

The Nature paper further describes laboratory tests in which an existing anti-inflammatory inhibits caspase - 1, thereby preventing pyroptosis and breaking the cycle of cell death and inflammation.

Further testing in the laboratory dish showed that hematopoietic stem cells from the sleep - deprived mice responded less strongly than their peers to naturally occurring chemical signals that trigger cellular migration.

Previous studies have subjected phytoplankton to oil in laboratories to test their sensitivity and found differences in the impact on oceanic vs. coastal phytoplankton and differences when phytoplankton were in nutrient - rich or nutrient - poor water, as well as damage to some phytoplankton cells at various concentrations of oil.

The researchers then tested the capacity of the modified cells to kill human multiple myeloma cells in laboratory studies and an animal model.

According to the authors of the study, in future researches it will be necessary to know about the action mechanism of the new products - highly selective and with low cell toxicity on in vitro tests - and broaden preclinical studies with laboratory animal models.

Preliminary safety testing on cells grown in the laboratory showed the drugs were not toxic to mammalian cells because they only inhibit the bacterial ribosomes and not mammalian ribosomes.

He was scouring the scientific literature when he hit upon an article describing high - throughput screening, a new technique that used robots to test the therapeutic properties of thousands of chemical compounds a day in cells in laboratory dishes.

«Our laboratory results are promising and certainly provide encouragement to test this treatment clinically in patients with small cell lung cancer.»

The team tested the technology — which they dubbed «degronimids» — in laboratory samples of leukemia cells.

When tested in laboratory samples of leukemia cells and in animals with human - like leukemia, the approach caused cancer cells to die much more quickly than with conventional targeted therapies.

A laboratory blood test developed at Johns Hopkins for the diagnosis of a rare genetic red blood cell disorder also shows promise in identifying HELLP syndrome, a life - threatening high blood pressure condition affecting 1 percent of all pregnant women that causes hypertension along with end organ damage, researchers report in the May issue of the journal Experimental Hematology.

The new solar cell achieved 40.7 percent efficiency under such concentrated light at the testing center at the National Renewable Energy Laboratory in Colorado.

Next, in a laboratory test - tube experiment they found that mixing serum from women with classic or atypical HELLP together with a monoclonal antibody the blocks complement, resulted in a significant decrease in the killing of cells in the modified Ham test — from about a 34 % kill rate down to a 5 % kill rate, the amount seen in healthy individuals.

The availability of centralized facilities will allow rapid access of investigators in NOAC, as well as investigators new to alcohol research, to the tissues and cells needed to test novel and innovative hypotheses without the delay of each PI developing these techniques in each of their own laboratories.

The INL electrochemical clean energy laboratory has capabilities in materials synthesis, cell fabrication, and high - throughput testing and characterization capabilities (up to 8 channels which are expandable).

Researchers at Pacific Northwest National Laboratory and East China Normal University devised and tested a thin - about as thin as the skin of a soap bubble - film composed of a special type of molecules called peptoids that can repair itself, similar to the self - repair seen in cells of living organisms.

Findings from basic research, such as studies of cancer cells in the laboratory, can ultimately define research questions to study in humans, such as helping to identify drugs to test in clinical trials.

In the early 1980s, Eaves, the founding director of the British Columbia Cancer Agency's Terry Fox Laboratory, started buying up the best fetal calf serum by the bucket - full, bringing it to his lab, and rigorously testing it for its ability to support the growth of hematopoietic stem cells.

In 2012, when Tonegawa Laboratory, a neuroscience research lab at MIT, developed a way to label engram cells, this opened the door to new ways to test memory consolidation theories.

In collaboration with several drug companies and academic laboratories, we developed furin inhibitors active both in the test tube and in cell culturIn collaboration with several drug companies and academic laboratories, we developed furin inhibitors active both in the test tube and in cell culturin the test tube and in cell culturin cell culture.

The team went on to test how sarcosine affected the behavior of cancer cells grown in the laboratory.

Furthermore, because the TRG locus is rearranged before the TRB locus and these clonal rearrangements persist, even in alpha - beta T cells, laboratories testing for IGH, IGK and the TRG together are likely to detect at least one clonal biomarker target in the vast majority of hematologic malignancies.

They were financed by Advanced Cell Technology, a biotech company with laboratories in Marlborough, Massachusetts, that recently won approval from the U.S. Food and Drug Administration to test the treatment in 24 patients suffering from either dry advanced macular degeneration, or a juvenile form of the disease known as Stargardt's.

This discovery stemmed from a novel series of tests, developed by Nakamura's laboratory, that measure energy levels in cells.

Idaho National Laboratory (INL) has a well - established capability for performance testing of solid - oxide cells and stacks, operating in the electrolysis mode for efficient hydrogen production from steam.

Before any tests or trials take place on patients, millions of chemical compounds are tested on cells in the laboratory, in a bid to detect adverse effects.

The extract was tested in laboratory studies using colon cancer cells grown in culture.

The team is utilizing SU2C's unique «tumor organoid» technology in which an individual patient's tumor cells are grown in the laboratory, creating «mini tumors» which can then be tested to see if a particular treatment is optimal.

SAN DIEGO, March 28, 2017 (GLOBE NEWSWIRE)-- Invivoscribe ® Technologies Inc., a global company with decades of experience providing internationally standardized clonality and biomarker testing solutions for the fields of oncology, personalized molecular diagnostics ®, and personalized molecular medicine ®, reports that its next - generation sequencing (NGS) LymphoTrack ® Assay kits are being used by its LabPMM ® clinical laboratories, pharmaceutical partners, and cancer centers to identify and monitor chimeric antigen receptor T - cells (CAR - T) and engineered T - cell receptors in peripheral blood of subjects in support of immuno - therapeutic drug development and treatment regimen development for both hematologic and solid tumors.

In laboratory studies, the turmeric (curcumin) herb reduced the growth of cancerous cells and inhibited the growth of tumors in the laboratory test animalIn laboratory studies, the turmeric (curcumin) herb reduced the growth of cancerous cells and inhibited the growth of tumors in the laboratory test animalin the laboratory test animals.

Cancer studies show that gamma linolenic acid (GLA) can kill 40 different kinds of cancer cells in the laboratory tissue tests without harming healthy tissue.

This lag in energy production tends to occur earlier than changes in blood cell production, so the muscle fatigue and changes in concentration are likely to be noticeable long before laboratory testing shows low blood cell production.

Shown in laboratory tests to PROTECT CARTILAGE cells from breakdown.

In - house laboratory tests include: standard blood chemistries, red and white blood cell counts, parvo virus, heartworm infection, giardia, feline leukemia and feline immunodeficiency virus.

DNA test kits typically entail taking a swab of cells from your dog's mouth with a cotton - tipped applicator, sealing it in a sterile tube and mailing it back to the laboratory.

Your veterinarian may use a test called a fine needle aspiration to take a sample of cells for testing in the laboratory.

Some cancers first found in the perineal area have actually come from other areas of the body, and the laboratory tests and X-rays help find the origin of these cancer cells.

Laboratory tests on the blood of these patients show, besides regenerative anemia, increased red cell pigments free in the blood and urine.

In addition, any necessary laboratory tests will be done such as a blood urea nitrogen (BUN), complete blood count (CBC), packed cell volume (PCV), urinalysis, and a serum biochemical profile to look for elevated ammonia and amino acids which are classic confirmations of cyanide poisoning.

This is the process, tested so far only at laboratory scale, of growing pork, chicken, or beef through cell culture in vats instead of raising and slaughtering animals.

The researchers conducted tests by growing both healthy human - lung cells and precancerous human - lung cells in laboratory flasks.

Lab Technician II — TRL Plasma Laboratories — January 2013 — Present • Monitor the heat sealing and aseptic sampling of plasma units; place units of plasma into freezer in timely manner in order to ensure quality of product • Label plasma samples and units properly and store according to policy; manage an average of 50 different plasma units on a regular basis • Evaluate refrigerator and freezer temperatures ad inform supervisor if equipment is malfunctioning • Maintain efficient and clean work environment and ensure inventory is stocked properly; answer phones and answer questions or transfer calls to appropriate departmentLab Technician I — ABC Medical Technologies, Inc. — May 2007 — January 2013 • Operated laboratory equipment, such as cell counters and microscopes, to analyze urine, blood, and tissue samples; recorded both normal and abnormal findings; had less than a.1 percent margin of error in sample findings • Used computerized instruments and automated equipment to perform multiple tests at one time; maintained calibration and proper function of equipment on a regular basis • Entered data from tests into physician reports; discussed abnormal results with supervisor and re-ran tests before logging data into patient's medical record