For using light to manipulate the activities of brain
cells in living animals and for enabling rapid alterations to the genomes of living organisms.
Howard Hughes Medical Institute researchers have successfully targeted unnatural sugar molecules with chemically unique functional groups onto the surfaces of
cells in living animals without altering...
Using a novel approach for imaging the movement of immune
cells in living animals, researchers from the Massachusetts General Hospital (MGH) Center for Immunology and Inflammatory Diseases (CIID) have identified what appear to be the initial steps leading to joint inflammation in a model of inflammatory arthritis.
For 50 years of brilliant creativity in biomedical science — exemplified by his legendary work on the genetic code; his daring introduction of the roundworm Caenorhabditis elegans as a system for tracing the birth and death of
every cell in a living animal; his rational voice in the debate on recombinant DNA; and his trenchant wit.
Not exact matches
Memphis Meats, meanwhile, innovates by creating products that come from
animal cells in a lab — not
live animals — to deliver a true «meaty» taste.
While Beyond Meat is making its products out of plants, Memphis Meats grows meat
in tanks by feeding oxygen, sugar, and other nutrients to
living animal cells.
What guides the process
in all
living things is DNA, which regulates every
cell of every plant and
animal.
«
In its 4.6 billion years circling the sun, the Earth has harbored an increasing diversity of
life forms: for the last 3.6 billion years, simple
cells (prokaryotes); for the last 3.4 billion years, cyanobacteria performing ph - otosynthesis; for the last 2 billion years, complex
cells (eukaryotes); for the last 1 billion years, multicellular
life; for the last 600 million years, simple
animals; for the last 550 million years, bilaterians,
animals with a front and a back; for the last 500 million years, fish and proto - amphibians; for the last 475 million years, land plants; for the last 400 million years, insects and seeds; for the last 360 million years, amphibians; for the last 300 million years, reptiles; for the last 200 million years, mammals; for the last 150 million years, birds; for the last 130 million years, flowers; for the last 60 million years, the primates, for the last 20 million years, the family H - ominidae (great apes); for the last 2.5 million years, the genus H - omo (human predecessors); for the last 200,000 years, anatomically modern humans.»
Thus, the transition from instinct to reason results
in the radical transformation of the
animal into man; matter as it evolves toward the
cell becomes radically transformed into
living matter; and vegetative
life becomes qualitatively changed into conscious
life.
A thin layer of
living cells spread out
in two dimensions over the globe could accomplish little; but concentrated
in three - dimensional forms,
cells constitute the vast and varied world of plant and
animal life.
The heuristic field is narrowed down; and a return is then seldom made to the question of what
life is as we spontaneously recognize it
in the achievements of
animals and
cells.
Evidence of the fact that union differentiates is to be seen all round us —
in the bodies of all higher forms of
life,
in which the
cells become almost infinitely complicated according to the variety of tasks they have to perform;
in animal associations, where the individual «polymerises» itself, one might say, according to the function it is called upon to fulfil;
in human societies, where the growth of specialization becomes ever more intense; and
in the field of personal relationships, where friends and lovers can only discover all that is
in their minds and hearts by communicating them to one another.
This depends upon there being a brain, an arrangement of
cells in a particular part of the body which by reason of its peculiar coordination makes the given routing able to «know»
in a distinctively human manner — quite different from, although certainly continuous with, the sort of «knowing» that is possible for the higher grades of
animal life.
(Cf. the phenomenon of the «runners» at first connected with the mother plant and then separated from it; the fluid transition between various plants and
animals which appear to be one; the germ -
cell inside and outside the parent organism, etc.)
Living forms which present what are apparently very great differences
in space and time can ontologically have the same morphological principle, so that enormous differences of external form can derive from the material substratum and chance patterns of circumstance without change of substantial form (caterpillar - chrysalis butterfly).
This spontaneity may be minimal for protons and electrons, but
in the course of the evolutionary advance, sustained until now, it has manifested itself
in ever richer forms as the vitality of
living cells, the conscious activity of the higher
animals, and the self - conscious freedom of man.
There would,
in other words, be no difference
in principle (but only
in complexity) between
living cells and
living animals, on the one hand, and rocks and billiard balls, on the other.
Example
in point: Opposition to embryonic stem
cell / human cloning research: It isn't anti science to oppose treating nascent human
life like a corn crop or manufacturing embryos, anymore than it is anti science than the
Animal Welfare Act the proscribes what can and can't be done
in scientific research with some mammals.
Then he contends that the
living occasions of a
cell «
in abstraction from the inorganic occasions of the
animal body» do not «form a corpuscular sub-society, so that each
living occasion is a member of an enduring entity with its personal order» (PR 158).
The objects of his study range from a class of molecules that have the basic self - duplicating property of
living things, through
cells which suggest purely physical systems, through
animals which give increasing evidence of having minds, to human beings
in whom streams of consciousness seem to involve continual choices of action, at the opposite pole from control by impersonal laws of nature.
Higher
animals all seem to contain at least one such society, called a «
living person,» present
in the body
in addition to the
cells and molecules of the central nervous system, even though dependent upon them.
Dietary Methylglyoxal (MGO) is a compound that occurs naturally when glucose is made available to a
living cell in the human body, plant or
animal.
This ancient theory, recounted by Pliny the Elder, is one of the many bizarre early attempts to explain one of
life's greatest mysteries — how a nearly uniform egg
cell develops into an
animal with dozens of types of
cells, each
in its proper place.
Scientists are forced either to experiment on whole
animals, which is expensive, raises ethical issues and may not predict effects
in humans, or to perform tests on microscopic human
cells found
in tissue cultures, which have been altered to
live forever and bear little relation to actual
living, breathing people.
In animal models, the researchers found that using microRNA to disrupt cells in the brain's prefrontal cortex — a region associated with complex planning and decision - making — affected learning and memory later in lif
In animal models, the researchers found that using microRNA to disrupt
cells in the brain's prefrontal cortex — a region associated with complex planning and decision - making — affected learning and memory later in lif
in the brain's prefrontal cortex — a region associated with complex planning and decision - making — affected learning and memory later
in lif
in life.
«These predictive algorithms seem to do a good job when CRISPR is performed
in cells or tissues
in a dish, but whole genome sequencing has not been employed to look for all off - target effects
in living animals,» says co-author Alexander Bassuk, MD, PhD, professor of pediatrics at the University of Iowa.
The work
in animals and
cells also may not fully mimic real
life.
A class of small molecules found
in grapes, red wine, olive oil, and other foods extends the
life of yeast
cells by approximately 70 % and activates genes known to extend
life span
in laboratory
animals.
In a 1967 paper published in the Journal of Theoretical Biology, Margulis suggested that mitochondria and plastids — vital structures within animal and plant cells — evolved from bacteria hundreds of million of years ago, after bacterial cells started to collect in interactive communities and live symbiotically with one anothe
In a 1967 paper published
in the Journal of Theoretical Biology, Margulis suggested that mitochondria and plastids — vital structures within animal and plant cells — evolved from bacteria hundreds of million of years ago, after bacterial cells started to collect in interactive communities and live symbiotically with one anothe
in the Journal of Theoretical Biology, Margulis suggested that mitochondria and plastids — vital structures within
animal and plant
cells — evolved from bacteria hundreds of million of years ago, after bacterial
cells started to collect
in interactive communities and live symbiotically with one anothe
in interactive communities and
live symbiotically with one another.
This year those breakthroughs include tools for reprogramming
living cells and rendering lab
animals transparent; ways of powering electronics with sound waves and saliva; smartphone screens that correct for the flaws
in your vision; Lego - like atomic structures that could produce major advances
in superconductivity research; and others.
One would culture thin sheets of meat, seeded by
cells from a
living animal, on a reusable polymer scaffold; the other would grow meat on small edible beads that stretch with changes
in temperature.
This unique organization of tubulin is preserved among all
living plant and
animal cells, because it is essential for way
in which microtubules assemble, Al - Bassam said.
Last spring the team reported that their fibers induced the formation of new blood vessels
in both
cell cultures and
living animals.
Direct recordings from the neurons of
live mice showed the same pattern:
Animals that had gone through a stressful procedure had more bursting
cells in the lateral habenula.
That DNA molecule happens to reside
in a developing egg
cell within an ape - like
animal living in Africa.
«They are more true - to -
life than
cells in dishes and more human - like than
animal models,» said Hamilton.
Her
cells live on
in animals infected with DFTD today.
But, counter-intuitively, this mass
cell death might be the very thing that makes the
animals so long -
lived: it could be a natural mechanism their bodies use to clear precancerous
cells, stopping tumors
in their tracks.
Other techniques exist for remotely controlling the activity of
cells or the expression of genes
in living animals.
Biologists, physicists, mathematicians, and computer scientists have begun cooperating on a sophisticated «systems biology» aimed at understanding how the countless molecular interactions at the heart of
life fit together
in the workings of
cells, organs, and whole
animals.
To better determine the role of specific chemoattractants
in type III hypersensitivity, lead author Yoshishige Miyabe, MD, PhD, a research fellow
in Luster's lab, used multiphoton intravital microscopy — an imaging technology pioneered for studies of immune
cell movements
in living animals by CIID investigator and co-author Thorsten Mempel, MD, PhD — to follow
in real time the development of IC - induced arthritis
in a mouse model of rheumatoid arthritis.
Now scientists are figuring out how to observe astrocytes
in living animals and learning even more about the
cells» abilities.
ATP (adenosine triphosphate) is the main energy source inside a
cell and is considered to be the high energy molecule that drives all
life processes
in animals and humans.
The ability to automate morphology assays on 3D
cell cultures is a powerful tool, but some scientists are now pushing the technology even further, with algorithms that can classify structures
in living animals and clinical specimens.
Complex phenomena — which we have so far only been able to study
in live animals - can now be investigated
in simple laboratory experiments using cultivated
cells,» says postdoc Hans Christian Cederberg Helms from the Department of Pharmacy.
«This landmark study draws the conclusion
in pre-clinical
animal studies that stem
cell therapy for disc degenerative disease might be a potentially effective treatment for the very common condition that affects people's quality of
life and productivity,» said the senior author, Wenchun Qu, MD, PhD, of the Mayo Clinic
in Rochester, Minn..
Using a nuclear protein expressed
in follicle stem
cells (FSCs), the researchers found that castor, which plays an important role
in specifying which types of brain
cells are produced during embryonic development, also helps maintain FSCs throughout the
life of the
animal.
As the
cells mature, they must also be stimulated to move as they would be by bone growth and body movement
in a
living animal.
Billions of microbial
cells live in the guts of humans and other
animals.
Researchers at Boston Children's Hospital have, for the first time, visualized the origins of cancer from the first affected
cell and watched its spread
in a
live animal.
The use of
cell surface markers to isolate specific
cell populations is one common method for separating
cells; however, isolating
live cells based on their RNA expression is a powerful new way enabling the study of small
cell niches
in nongenetically modified
animal models and human tissue.