Sentences with phrase «cells in obese mice»

Not exact matches

In the study, mice were given food until they became obese, and were then fed the drug, which increases the cellular metabolism of obesity - linked white fat cells.

When tumor cells that no longer express CCR3 are implanted in the prostates of mice, tumor progression and dissemination are significantly reduced, especially in obese mice.

(Blaser's group reported earlier this month in Cell that giving mice penicillin soon after birth changed their gut microbiome and made them much more likely to be obese as adults.)

The drug, SRT1720, kept mice with high - calorie diets from becoming obese or diabetic, according to a study published in Cell Metabolism [subscription required].

In humans, as in mice, fat cells of the obese already produced plenty of leptin — more in fact than those of their thin counterparts, since the level of leptin was directly proportional to the amount of faIn humans, as in mice, fat cells of the obese already produced plenty of leptin — more in fact than those of their thin counterparts, since the level of leptin was directly proportional to the amount of fain mice, fat cells of the obese already produced plenty of leptin — more in fact than those of their thin counterparts, since the level of leptin was directly proportional to the amount of fain fact than those of their thin counterparts, since the level of leptin was directly proportional to the amount of fat.

Remarkably, the same healing effect was produced when B cells from older obese diabetic mice were applied to acute wounds in similarly aged, obese diabetic mice.

The U-M study explains how increased cAMP in fat cells promotes the secretion of the hormone interleukin - 6, which signals the liver to stop producing glucose — thus improving overall blood sugar levels in obese diabetic mice.

In research published in December 2013, the investigators found that high levels of IKK - ε and TBK1 meant that certain receptors in the fat cells of obese mice were unable to respond to neurotransmitters called catecholamines, which are generated by the sympathetic nervous system and promote «fat - burning.&raquIn research published in December 2013, the investigators found that high levels of IKK - ε and TBK1 meant that certain receptors in the fat cells of obese mice were unable to respond to neurotransmitters called catecholamines, which are generated by the sympathetic nervous system and promote «fat - burning.&raquin December 2013, the investigators found that high levels of IKK - ε and TBK1 meant that certain receptors in the fat cells of obese mice were unable to respond to neurotransmitters called catecholamines, which are generated by the sympathetic nervous system and promote «fat - burning.&raquin the fat cells of obese mice were unable to respond to neurotransmitters called catecholamines, which are generated by the sympathetic nervous system and promote «fat - burning.»

Ozcan realized that inflammation might help when he noticed that in obese diabetic mice, XBP - 1s failed to enter the cell nucleus, where insulin function is regulated.

«Understanding how the drug also enables crosstalk between fat cells and the liver in obese mice allows us to see more of the amlexanox picture — and also sheds light on communication between different tissues in the body.»

New study shows that in obese mice a hormone secreted by fat cells goes undetected and the regulation of appetite is thrown off; findings could trigger treatment

The fraction of F4 / 80 - expressing cells was greater in moderately obese mice (b and e) and greatest in the severely obese Lepob / ob mice (c and f).

Adipose tissue within muscle contained significant numbers of F4 / 80 + macrophages, and the percentage of F4 / 80 + cells within this adipose tissue was markedly increased in obese mice compared with lean mice (41 % ± 4 % of macrophages vs. 12 % ± 2 % of macrophages, respectively; P < 0.005, mean ± SD)(Figure 4).

We calculated the average adipocyte cross-sectional area and the percentage of F4 / 80 - expressing cells in the perigonadal, perirenal, mesenteric, and subcutaneous inguinal adipose tissue depots from Ay / + female, Lepob / ob female, lean male, and diet - induced obese (DIO) male mice.

To determine whether adipose tissue macrophages express any molecules implicated in obesity - associated complications, we isolated three cell populations from the parametrial adipose tissue of three obese B6.V Lepob / ob mice: (a) an adipocyte - enriched population, (b) a stromal vascular macrophage F4 / 80 + population, and (c) an F4 / 80 — stromal vascular population.

In genetically programed insulin - resistant obese mice with increased appetite and reduced physical activity, targeted restoration of Pomc function only within 5 - hydroxytryptamine 2c receptor containing cells induces sex differences in energy balance (267In genetically programed insulin - resistant obese mice with increased appetite and reduced physical activity, targeted restoration of Pomc function only within 5 - hydroxytryptamine 2c receptor containing cells induces sex differences in energy balance (267in energy balance (267).

The activation of a protein pathway in fat cells in the mice allowed the animals to be fed a high - fat diet without becoming obese.

CD36 - and GPR120 - mediated Ca2 + signaling in human taste bud cells mediates differential responses to fatty acids and is altered in obese mice.

there is a 5-fold increase in number of insulin - secreting cells per islet in obese mice with high insulin secretion

After exercising for six weeks, both obese and lean mice showed a significant reduction in the overall size of fat cells and the overall amount fat in the marrow.

In a study of obese mice that received a diet rich in either coconut or safflower oil, mice that received the coconut oil were found to have made much less fat cells than mice that received the safflower oiIn a study of obese mice that received a diet rich in either coconut or safflower oil, mice that received the coconut oil were found to have made much less fat cells than mice that received the safflower oiin either coconut or safflower oil, mice that received the coconut oil were found to have made much less fat cells than mice that received the safflower oil.

In 1994, it was discovered that a protein hormone called leptin, which is released from fat cells and monitored by the brain, was deficient in a certain strain of genetically mutated obese micIn 1994, it was discovered that a protein hormone called leptin, which is released from fat cells and monitored by the brain, was deficient in a certain strain of genetically mutated obese micin a certain strain of genetically mutated obese mice.

Calorie Restriction - like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans Cell Metabolism 2011 (Nov 2); 14 (5): 612 — 622 ~ FULL TEXT The result of just 30 days on resveratrol were impressive: (1) The same gene regulators (AMPK, SIRT1 and PGC - 1a) were activated in this study as are activated by caloric restriction and resveratrol in mice and endurance training in humans.

This study has examined the effect of alpha - lipoic acid on glucose uptake by cultured L6 muscle cells and different types of skeletal muscles in normal lean (+ / +) and severely insulin - resistant, obese - diabetic (ob / ob) mice.