Sentences with phrase «cells in our bone marrow produce»

With amyloidosis, cells in the bone marrow produce antibodies that can not be broken down.

Not exact matches

This monocyte production created a vicious cycle whereby high blood sugar levels boosted neutrophil numbers, leading to excess secretion of S100A8 / S100A9, which in turn stimulated bone marrow cells to produce more monocytes.

Blood stem cells are found in bone marrow and produce all blood cells in the body.

The diet increased the levels of leptin — a hormone produced by fat cells that usually signals satiety in the brain — in the bone marrow, which promoted the development of fat cells instead of bone cells.

Nayernia says that researchers have produced the same early - stage sperm cells in mice from bone marrow cells taken from female mice.

In DBA, a mutation prevents a patient's bone marrow from producing normal quantities of red blood cells, resulting in severe, sometimes life - threatening anemiIn DBA, a mutation prevents a patient's bone marrow from producing normal quantities of red blood cells, resulting in severe, sometimes life - threatening anemiin severe, sometimes life - threatening anemia.

In addition to suppressing the mature blood cells battling against the infection, malfunctioning of this signaling system results in permanent damage to the body's blood producing cells — called hematopoietic stem cells — that are located in the bone marroIn addition to suppressing the mature blood cells battling against the infection, malfunctioning of this signaling system results in permanent damage to the body's blood producing cells — called hematopoietic stem cells — that are located in the bone marroin permanent damage to the body's blood producing cells — called hematopoietic stem cells — that are located in the bone marroin the bone marrow.

Aifantis, the chair of the Department of Pathology at NYU Langone and a member of its Perlmutter Cancer Center, and an early career scientist at the Howard Hughes Medical Institute, says experiments in his laboratory had shown that leukemia - initiating cells concentrate in the bone marrow near CXCL12 - producing blood vessels.

MDS are a group of bone marrow disorders in which the bone marrow doesn't produce enough healthy blood cells.

In the paper that is now published, they make the stem cells in the bone marrow to produce more telomerase, thus enabling them to repair their excessively shortened telomereIn the paper that is now published, they make the stem cells in the bone marrow to produce more telomerase, thus enabling them to repair their excessively shortened telomerein the bone marrow to produce more telomerase, thus enabling them to repair their excessively shortened telomeres.

Everybody has suPAR, which is produced by bone marrow cells, in their blood, with normal levels around 2400 picogram per milliliter (pg / ml).

«Ferric citrate binds the phosphorus in food and also increases iron in the blood, and it allows patients to need less or no IV iron and medicines to make their bone marrow produce more blood cells,» said Dr. Lewis.

Bone marrow biopsies often produce limited numbers of tumor cells to test — as few as 50,000 tumor cells in this study — but for this technique that is enough to test many different drugs and drug combinations.

Recent research has suggested that tumor - infiltrating myeloid cells are initially produced in the bone marrow.

Both the number and activity of osteoblasts — cells that produce and reshape bone tissue — were increased within the bone marrow of mice with lung tumors compared with cancer - free animals; and reducing the number of osteoblasts in mice not only limited neutrophil infiltration of tumors but also interrupted tumor progression.

While megakaryocytes are best known for producing platelets that heal wounds, these «mega» cells found in bone marrow also play a critical role in regulating stem cells according to new research from the Stowers Institute for Medical Research.

Haemoglobin is produced by erythroblasts, cells in the bone marrow that mature into red blood cells.

Stem cells in the bone marrow are normally responsible for producing blood.

Cincinnati Children's researchers report in Nature Immunology a new mechanism that controls blood cell function and several possible molecular targets for treating myelodysplasia syndromes (MDS)-- a group of pre-malignant disorders in which bone marrow does not produce enough healthy blood cells.

As part of a clinical trial conducted at Northwestern University in Chicago, Illinois, Ildstad and colleagues extracted bone marrow - producing cells from kidney donors and then removed cells likely to cause GVHD while expanding the number of «facilitating cells» that make an organ recipient's system more receptive.

Because bone marrow produces immune cells, the procedure led to a brief period in which the recipient's immune system blended with that of the donor.

It specifically affects antibody - producing white blood cells found in the bone marrow, called plasma cells.

During a viral infection, the body needs various defense mechanisms — amongst other things, a large number of white blood cells (leukocytes) must be produced in the bone marrow within a short period of time.

In these therapies, the patient's own blood - producing bone marrow cells are treated with radiation and chemotherapy, and the blood of a twin or closely matched donor is instilled.

In diseases like leukemia, a kind of cancer, the bone marrow produces abnormal blood cells.

In separate experiments reported in Nature — one with mice, the other transplanting human stem cells into mouse bone marrow — researchers demonstrated techniques with the potential to produce all types of blood cellIn separate experiments reported in Nature — one with mice, the other transplanting human stem cells into mouse bone marrow — researchers demonstrated techniques with the potential to produce all types of blood cellin Nature — one with mice, the other transplanting human stem cells into mouse bone marrow — researchers demonstrated techniques with the potential to produce all types of blood cells.

These stem cells end up in the bone marrow and start producing new blood cells.

In a third of MDS cases, over time, very immature bone marrow cells called blasts may increase in number and fill the bone marrow, displacing the normal red and white blood cells and platelets that are produced therIn a third of MDS cases, over time, very immature bone marrow cells called blasts may increase in number and fill the bone marrow, displacing the normal red and white blood cells and platelets that are produced therin number and fill the bone marrow, displacing the normal red and white blood cells and platelets that are produced there.

Until now, blood cell production was ascribed solely to bone marrow, but studies on mice have found that the majority of the body's platelets are produced in the lungs, as is a backup reservoir of blood stem cells that can step in when those in the bone marrow run dry.

These factors include chemokine (C - X-C motif) ligand 12 (CXCL12), a chemokine produced by bone marrow mesenchymal cells that functions as a chemoattractant and survival factor for cells bearing the chemokine (C - X-C motif) receptor 4 (CXCR4), and insulin - like growth factor 1 (IGF - 1), a factor that is stored in the bone matrix and released during osteolysis (28).

Bones also allow us the gift of movement, they act as a reservoir of minerals to maintain acid / base balance in the blood and they actually produce red blood cells, white blood cells and platelets in the bone marrow.

In that procedure, doctors use chemotherapy drugs to wipe out the patient's existing bone marrow stem cells — which are producing the faulty red blood cells.

A more recent treatment option has been to administer a bone marrow transplant following successful chemo, in hopes that new white blood cells produced by the donated marrow will be able to find and kill the cancerous blood cells circulating in the patient's body, he said.

In addition to not producing RBCs, the unhealthy bone marrow is not producing healthy white blood cells (WBCs) either.

When white blood cells multiply in an abnormal and uncontrolled way, these immature cells take over, literally crowding the bone marrow thereby preventing it from producing healthy blood cells and causing a shortage of red blood cells.

Blood cells are produced in the center spongy part of the bone called the marrow.

High estrogen levels in an intact female that stays in heat or in a ferret with adrenal gland disease can cause the bone marrow to stop producing red blood cells and cause a moderate to severe anemia.

The bone marrow also produces red blood cells, whose main function is to transport oxygen to the body's cells, and platelets, which play an important role in blood clotting.

Stem cells that live in that bone marrow produce a specialized white blood cell called a B cell.

Red blood cells, produced in bone marrow, carry oxygen throughout the body.

Trapped Neutrophil Syndrome in Border Collies where the bone marrow produces them but can not be released into the blood cells.

In chronic renal failure, the pet's kidneys cease to produce sufficient amounts of a hormone, erythropoietin, necessary for blood cell formation in the bone marroIn chronic renal failure, the pet's kidneys cease to produce sufficient amounts of a hormone, erythropoietin, necessary for blood cell formation in the bone marroin the bone marrow.

This is because toxic waste in their blood stream depresses their bone marrow — the source of red blood cells - and because their kidneys no longer produce enough erythropoietin, a hormone necessary to form red blood cells.

Red blood cells are normally produced by your dog or cat's bone marrow in endless look - alike clones.

The bone marrow, which produces blood cells, is also destroyed, resulting in anemia.

The only white blood cells that didn't originate in the dog or cat's bone marrow are its lymphocytes - those were produced in its lymphatic tissues (lymph nodes, etc.); In dogs and cats, those are also the ones most likely to become cancerouin the dog or cat's bone marrow are its lymphocytes - those were produced in its lymphatic tissues (lymph nodes, etc.); In dogs and cats, those are also the ones most likely to become cancerouin its lymphatic tissues (lymph nodes, etc.); In dogs and cats, those are also the ones most likely to become cancerouIn dogs and cats, those are also the ones most likely to become cancerous.

When certain cells in your pet's immune system encounter an invader or a vaccine for the first time, some, released from your pet's bone marrow, produce antibody.

In addition to increased thirst and urine volume (often called PU / PD, meaning polyuria and polydipsia) over time a cat with CRD may become anemic, since the kidneys produce a hormone that stimulates the bone marrow to produce red blood cells.

The bone marrow should respond to anemia by producing more red blood cells; therefore, an increase in the number of immature cells called reticulocytes should be seen on lab results.

ACT - activated clotting time (bleeding disorders) ACTH - adrenocorticotropic hormone (adrenal gland function) Ag - antigen test for proteins specific to a disease causing organism or virus Alb - albumin (liver, kidney and intestinal disorders) Alk - Phos, ALP alkaline phosphatase (liver and adrenal disorders) Allergy Testing intradermal or blood antibody test for allergen hypersensitivity ALT - alanine aminotransferase (liver disorder) Amyl - amylase enzyme — non specific (pancreatitis) ANA - antinuclear antibody (systemic lupus erythematosus) Anaplasmosis Anaplasma spp. (tick - borne rickettsial disease) APTT - activated partial thromboplastin time (blood clotting ability) AST - aspartate aminotransferase (muscle and liver disorders) Band band cell — type of white blood cell Baso basophil — type of white blood cell Bile Acids digestive acids produced in the liver and stored in the gall bladder (liver function) Bili bilirubin (bile pigment responsible for jaundice from liver disease or RBC destruction) BP - blood pressure measurement BUN - blood urea nitrogen (kidney and liver function) Bx biopsy C & S aerobic / anaerobic bacterial culture and antibiotic sensitivity test (infection, drug selection) Ca +2 calcium ion — unbound calcium (parathyroid gland function) CBC - complete blood count (all circulating cells) Chol cholesterol (liver, thyroid disorders) CK, CPK creatine [phospho] kinase (muscle disease, heart disease) Cl - chloride ion — unbound chloride (hydration, blood pH) CO2 - carbon dioxide (blood pH) Contrast Radiograph x-ray image using injected radiopaque contrast media Cortisol hormone produced by the adrenal glands (adrenal gland function) Coomb's anti- red blood cell antibody test (immune - mediated hemolytic anemia) Crea creatinine (kidney function) CRT - capillary refill time (blood pressure, tissue perfusion) DTM - dermatophyte test medium (ringworm — dermatophytosis) EEG - electroencephalogram (brain function, epilepsy) Ehrlichia Ehrlichia spp. (tick - borne rickettsial disease) EKG, ECG - electrok [c] ardiogram (electrical heart activity, heart arryhthmia) Eos eosinophil — type of white blood cell Fecal, flotation, direct intestinal parasite exam FeLV Feline Leukemia Virus test FIA Feline Infectious Anemia: aka Feline Hemotrophic Mycoplasma, Haemobartonella felis test FIV Feline Immunodeficiency Virus test Fluorescein Stain fluorescein stain uptake of cornea (corneal ulceration) fT4, fT4ed, freeT4ed thyroxine hormone unbound by protein measured by equilibrium dialysis (thyroid function) GGT gamma - glutamyltranferase (liver disorders) Glob globulin (liver, immune system) Glu blood or urine glucose (diabetes mellitus) Gran granulocytes — subgroup of white blood cells Hb, Hgb hemoglobin — iron rich protein bound to red blood cells that carries oxygen (anemia, red cell mass) HCO3 - bicarbonate ion (blood pH) HCT, PCV, MHCT hematocrit, packed - cell volume, microhematocrit (hemoconcentration, dehydration, anemia) K + potassium ion — unbound potassium (kidney disorders, adrenal gland disorders) Lipa lipase enzyme — non specific (pancreatitis) LYME Borrelia spp. (tick - borne rickettsial disease) Lymph lymphocyte — type of white blood cell MCHC mean corpuscular hemoglobin concentration (anemia, iron deficiency) MCV mean corpuscular volume — average red cell size (anemia, iron deficiency) Mg +2 magnesium ion — unbound magnesium (diabetes, parathyroid function, malnutrition) MHCT, HCT, PCV microhematocrit, hematocrit, packed - cell volume (hemoconcentration, dehydration, anemia) MIC minimum inhibitory concentration — part of the C&S that determines antimicrobial selection Mono monocyte — type of white blood cell MRI magnetic resonance imaging (advanced tissue imaging) Na + sodium ion — unbound sodium (dehydration, adrenal gland disease) nRBC nucleated red blood cell — immature red blood cell (bone marrow damage, lead toxicity) PCV, HCT, MHCT packed - cell volume, hematocrit, microhematocrit (hemoconcentration, dehydration, anemia) PE physical examination pH urine pH (urinary tract infection, urolithiasis) Phos phosphorus (kidney disorders, ketoacidosis, parathyroid function) PLI pancreatic lipase immunoreactivity (pancreatitis) PLT platelet — cells involved in clotting (bleeding disorders) PT prothrombin time (bleeding disorders) PTH parathyroid hormone, parathormone (parathyroid function) Radiograph x-ray image RBC red blood cell count (anemia) REL Rocky Mountain Spotted Fever / Ehrlichia / Lyme combination test Retic reticulocyte — immature red blood cell (regenerative vs. non-regenerative anemia) RMSF Rocky Mountain Spotted Fever SAP serum alkaline phosphatase (liver disorders) Schirmer Tear Test tear production test (keratoconjunctivitis sicca — dry eye,) Seg segmented neutrophil — type of white blood cell USG Urine specific gravity (urine concentration, kidney function) spec cPL specific canine pancreatic lipase (pancreatitis)-- replaces the PLI test spec fPL specific feline pancreatic lipase (pancreatitis)-- replaces the PLI test T4 thyroxine hormone — total (thyroid gland function) TLI trypsin - like immunoreactivity (exocrine pancreatic insufficiency) TP total protein (hydration, liver disorders) TPR temperature / pulse / respirations (physical exam vital signs) Trig triglycerides (fat metabolism, liver disorders) TSH thyroid stimulating hormone (thyroid gland function) UA urinalysis (kidney function, urinary tract infection, diabetes) Urine Cortisol - Crea Ratio urine cortisol - creatine ratio (screening test for adrenal gland disease) Urine Protein - Crea Ratio urine protein - creatinine ratio (kidney disorders) VWF VonWillebrands factor (bleeding disorder) WBC white blood cell count (infection, inflammation, bone marrow suppression)