Sentences with phrase «cells in rodents»

And he and his lab are excited about new studies showing that fasting seems to strengthen normal cells in rodents while making cancer cells more vulnerable.

Not exact matches

(According to Tao, the imprinted cells in the experiment proliferated and transferred healthy, functioning cardiac cells to the rodent.)
When placed at the site of a cancerous tumour in a rodent and «activated» by a scope with a light source, the compounds eradicated up to 100 % of cancer cells.
Zhang, by contrast, showed specifically how the technique could be used in the more complex (eukaryotic) cells of rhododendrons, rodents, and humans.
In 2011, the team was the first to report functional, lab - grown anal sphincters bioengineered from human cells that were implanted in immune - suppressed rodentIn 2011, the team was the first to report functional, lab - grown anal sphincters bioengineered from human cells that were implanted in immune - suppressed rodentin immune - suppressed rodents.
A new approach to tiny fuel cells implanted in rats enables the devices to generate electricity for months using sugar in the rodents» bodies
Partial reprogramming of cells within prematurely aging mice's bodies extended the rodents» average life span from 18 weeks to 24 weeks, researchers report December 15 in Cell.
To see which are involved in heart - cell division, Giacca's team tested 875 human microRNAs in cultured rodent heart muscle.
Now research in rodents suggests that gut microbes may alter the inventory of microRNAs — molecules that help keep cells in working order by managing protein production — in brain regions involved in controlling anxiety.
Using this biosensor in highly invasive breast cancer cells taken from rodents and humans, the Einstein team discovered that when an individual invadopodium forms and is actively degrading the ECM, its Rac1 levels are low; on the other hand, elevated Rac1 levels coincide with the invadopodium's disappearance.
A small proportion of the neurons in the lateral habenula fire several times in quick bursts, rather than firing once at regular intervals; the team found that «depressed» rodents had a lot more of these quick burst cells.
Researchers in France and Sweden have, over the past couple of years, shown that when BMAA is injected into rodents it gets incorporated into their eyes (pdf), where it could build up and potentially cause damage to cells in the retina.
To create mouse avatars, researchers implant some of a patient's cancer cells into rodents lacking a normal immune system and measure whether various drugs destroy the tumors that sprout in the animals.
Two years ago, he and his colleagues reported in Aging Cell that cutting the calories ingested by mice by 30 % for up to 4 weeks protected the rodents» kidneys when their blood supply was cut off and then restored.
Adult mice and other rodents sprout new nerve cells in memory - related parts of their brains.
MASTER HUNTER Nerve cells in a mouse's amygdala send messages that help the rodent chase and kill prey such as crickets, a new study shows.
New Scientist was unable to reach the Lisbon team members, but Jean Peduzzi - Nelson, a stem cell researcher at Wayne State University in Detroit, Michigan, who advised the team on their surgical technique — she had previously tested it on rodents — claims the clinic has given the therapy to about 140 people in total.
Studies in rodents and in human fetal beta cells have showed that the responses of very young beta cells to increases in blood glucose are blunted when compared to their more - mature counterparts.
In most cases, the animals» immune systems are compromised, or the rodents have been genetically engineered to rapidly spread mutant cells.
In this study, the team, which included Dr. Meerim Nurbaeva and Miriam Eckstein in Dr. Lacruz's lab, for the first time used freshly dissected enamel cells (ameloblasts) from rodent teeth to modulate physiological processes in order to understand the contribution of CRAC channels in enamel calcium signalinIn this study, the team, which included Dr. Meerim Nurbaeva and Miriam Eckstein in Dr. Lacruz's lab, for the first time used freshly dissected enamel cells (ameloblasts) from rodent teeth to modulate physiological processes in order to understand the contribution of CRAC channels in enamel calcium signalinin Dr. Lacruz's lab, for the first time used freshly dissected enamel cells (ameloblasts) from rodent teeth to modulate physiological processes in order to understand the contribution of CRAC channels in enamel calcium signalinin order to understand the contribution of CRAC channels in enamel calcium signalinin enamel calcium signaling.
Shifts in light exposure activated the UPR in those rodents» cells.
Partially paralyzed rodents walk almost normally after human embryonic or fetal brain stem cells repaired their spinal cord injuries in recent studies.
The lab of co-author Dr. Robert Bast Jr., an expert in ovarian cancer and vice president for translational research at MD Anderson, inserted gel - bound carbon nanotubes into the ovaries of rodents to mimic the accumulations that are expected for nanotubes linked to special antibodies that recognize tumor cells.
Studies in diabetic rodents suggest that diabetes may alter the intestine's mucosal lining, which is maintained and regenerated by intestinal stem cells; however, little is known about how this occurs and whether it is relevant to humans.
Dr Sottile added: «This new system gave us an advantage over previous rodent models as we could study more accurately how specifically human cells would be affected by a decrease in temperature.
Now, scientists have discovered a key component of this ancient navigational system in rats: a group of neurons called «speed cells» that alter their firing rates with the pace at which the rodents run.
So instead of studying the whole animals, he began isolating single nerve cells from the mole rats and investigating them in lab dishes to track the molecular basis of the rodent's pain insensitivity.
When scientists gave mice an oral drug called LM11A - 31 (designed to prevent neural degeneration in Alzheimer's patients) just hours after a complete spinal cord injury, it limited the death of cells that protect nerve fibers, allowing test rodents to retain their ability to walk and swim.
After obtaining cells from 31 species of nine rodent families, Gallardo's group used a stain to estimate the amount of nuclear DNA in each cell.
The authors found that if they blocked lactate release by glia or uptake by nerve cells, they produced a long - lasting prevention of cocaine relapse in rodents.
Scientists have shown that fuel cells implanted in rats can successfully generate electricity from sugar in the rodent's bodies.
«Stem cell strategy for boosting testosterone levels tested in rodents
For this proof of concept study, the scientists analyzed rodent cells» electrical activity for up to 30 days, reporting that the cells displayed characteristics and changes mimicking physiological responses described in literature.
«Nevertheless, we were very surprised to find active cryptochrome 1 in the cone cells of only two mammalian groups, as species whose cones do not contain active cryptochrome 1, for example some rodents and bats, also react to the magnetic field,» says Christine Nießner.
The cortex is the thin layer of cells on the surface of the brain that governs many functions, and in elephants it contains a greater variety of cell types (such as the extensively branched neuron pictured above) than is found in more frequently studied animals such as rodents and primates.
Researchers at University of California San Diego School of Medicine, with colleagues at the National Institute of Diabetes and Digestive and Kidney Diseases, the University of Manitoba and St. Boniface Hospital Albrechtsen Research Centre in Canada, have identified a molecular signaling pathway that, when blocked, promotes sensory neuron growth and prevents or reverses peripheral neuropathy in cell and rodent models of type 1 and 2 diabetes, chemotherapy - induced neuropathy and HIV.
Another important advance, says Pralle, is that whole networks of cells were activated for the first time, compared with single or small groups of neurons stimulated in previous monkey and rodent experiments.
The study in human cells and rodents appears November 28 in the journal Cell Reports.
The basics of glycogen biology are thought to be well established, but a study in rodents published July 5th in the journal Cell Metabolism turns long - standing assumptions on their head.
Also, research in other animal models, such as rodents, has shown anesthesia exposure early in life can lead to cell death in the brain and cognitive impairments.
Twenty - four hours after the injection, the researchers saw large numbers of immune system white blood cells in tissue samples of the rodent brains near the site of injury of those mice injected with the cytokine IL - 1b, but not in the brain tissue of the control group of mice.
In both primates and rodents, messages from the two eyes enters the brain through a small structure called the lateral geniculate nucleus or LGN, which is made of slivers of nerve cells, arranged like sponge in a layer cakIn both primates and rodents, messages from the two eyes enters the brain through a small structure called the lateral geniculate nucleus or LGN, which is made of slivers of nerve cells, arranged like sponge in a layer cakin a layer cake.
And whereas in rodents LGN cells may fire in response to one or both eyes, until now, neuroscientists had thought that in primates, LGN cells fired only in response to inputs from a single eye.
Previous research in rodent disease models has shown that transplanted oligodendrocyte precursor cells derived from embryonic stem cells and from human fetal brain tissue can successfully create myelin sheaths around nerve cells, sometimes leading to dramatic improvements in symptoms.
Studies in rodents have suggested that iPSC - derived cells used for transplantation may be rejected by the body's immune system.
What's more, in rodents the two - eye cells hook into sub-cortical areas of the brain such as the amygdala that help process emotion and fear responses, and areas that play a role in an animal's ability to spot salient events in its environment — an approaching cat for instance.
However, studies in rodents have suggested that the body may mount an immune response and destroy cells derived from iPSCs.
As in rodents, the researchers found one L - type («long - lasting») channel (CaV1.2) and two T - type («transient») channels (CaV3.2, and 3.3) in the human smooth muscle cells.
A newly discovered hormone in mice prompts the rodents to boost their production of pancreatic β cells, the ones that make insulin and are missing or not productive enough in patients with diabetes.
To see if all tissues in the respiratory tract have similarly forgetful immune cells, Wakim and colleagues tagged immune cells in mice and sprayed flu virus in the rodents» noses.
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