Scientists have made a key discovery that could speed up the production of
cells in the lab for studying diseases such as multiple sclerosis and Parkinson's disease.
They cultured
the cells in the lab for a day, then exposed them for 3 days to a virus which contained the normal gene for the receptor.
Not exact matches
In biologist John March's
lab at Cornell,
for example, they have armed probiotic bacteria with tools to make an intestinal
cell act like more like a pancreatic
cell.
This may entail making small holes
in the bone to allow new cartilage to grow (microfracture), taking cartilage from another part of the athlete's knee and transplanting it into the defect (osteochondral autograft transfer), taking cartilage
cells from the knee and then having them grown
in a
lab for later re-implantation (autologous chondrocyte implantation), or taking cartilage from a person who has passed away and placing it
in the defect (osteochondral allograft transfer).
Tau helps provide structure to brain
cells, is a marker
for axonal damage — and is also what McKee finds spotted throughout the brains she examines
in her Boston U.
lab.
These
cells are then sent to a genetics
lab for analysis while the embryos are safely frozen and stored
in our IVF
lab.
In a study reported online in Nature, she and her team revealed how the lymphatic system develops in the embryo and for the first time managed to grow lymphatic cells in the la
In a study reported online
in Nature, she and her team revealed how the lymphatic system develops in the embryo and for the first time managed to grow lymphatic cells in the la
in Nature, she and her team revealed how the lymphatic system develops
in the embryo and for the first time managed to grow lymphatic cells in the la
in the embryo and
for the first time managed to grow lymphatic
cells in the la
in the
lab.
Chemical biology and drug discovery usually depend on screens of
cells in lab dishes,
for example.
Shukla and colleagues discovered that a small drug molecule called BX795, which is sold to
labs for use
in experiments, helped clear HSV - 1 infection
in cultured human corneal
cells,
in donated human corneas, and
in the corneas of mice infected with HSV - 1.
Sharon joined Anglister's
lab for her master's project and Ph.D., studying the three - dimensional structure of a region
in the HIV - 1 protein envelope that helps the virus enter human
cells.
To investigate how the egg
cell manages to rid itself of such a resilient structure, Joana Pinto, a PhD student
in the Lénárt
lab, developed fluorescent tags
for mother and daughter centrioles
in a starfish egg
cell and recorded the entire process of eliminating them.
Strategies that boost the
cell's quality control programs, rather than disarm specific pathologic proteins, have looked promising
in lab animals that serve as models
for human neurodegenerative disorders including Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.
«I'm working with Professor Richard Oreffo and Dr Rahul Tare from the University's Centre
for Human Development, Stem
Cells and Regeneration who are trying to create and grow cartilage in the lab using a patients» own (autologous) stem cells to then be implanted back into the patient if they have a cartilage defect,» she expl
Cells and Regeneration who are trying to create and grow cartilage
in the
lab using a patients» own (autologous) stem
cells to then be implanted back into the patient if they have a cartilage defect,» she expl
cells to then be implanted back into the patient if they have a cartilage defect,» she explains.
For example, animal studies have shown that neurons derived
in the
lab from human embryonic stem
cells improve Parkinson's symptoms; however, any residual stem
cells associated with those neurons could form masses of unwanted
cells.
Starting
in 2007,
in the same French Institute of Health and Medical Research (INSERM)
lab where he did his Ph.D., Catelain worked to harness the potential of embryonic stem
cells for treating cardiac diseases.
This year those breakthroughs include tools
for reprogramming living
cells and rendering
lab animals transparent; ways of powering electronics with sound waves and saliva; smartphone screens that correct
for the flaws
in your vision; Lego - like atomic structures that could produce major advances
in superconductivity research; and others.
In science news around the world, the U.S. Food and Drug Administration (FDA) cracks down on stem
cell labs, Brazil opens one of its largest national reserves to gold and iron mining, and the International Atomic Energy Agency launches a global bank
for low - enriched uranium.
For the past several years, researchers have been modifying T
cells so they can attack leukemia, but the
cells must be painstakingly isolated from the patients themselves and grown
in a
lab.
Ong, who leads the Materials Virtual
Lab and is a faculty member
in the Sustainable Power and Energy Center at UC San Diego, uses a combination of high - throughput calculations and machine learning to discover next - generation materials
for energy applications, including batteries, fuel
cells and LEDs.
In a new study, Murphy, a molecular biologist at Princeton University, showed that long - lived bodily, or somatic, cells in Caenorhabditis elegans, a one - millimeter nematode commonly used as a model for aging studies in labs, activate genetic pathways completely separate from those found in long - lived egg, or oocyte, cell
In a new study, Murphy, a molecular biologist at Princeton University, showed that long - lived bodily, or somatic,
cells in Caenorhabditis elegans, a one - millimeter nematode commonly used as a model for aging studies in labs, activate genetic pathways completely separate from those found in long - lived egg, or oocyte, cell
in Caenorhabditis elegans, a one - millimeter nematode commonly used as a model
for aging studies
in labs, activate genetic pathways completely separate from those found in long - lived egg, or oocyte, cell
in labs, activate genetic pathways completely separate from those found
in long - lived egg, or oocyte, cell
in long - lived egg, or oocyte,
cells.
Researchers
in the Rice
lab of chemist and bioengineer Jeffrey Hartgerink had just such an experience with the hydrogels they developed as a synthetic scaffold to deliver drugs and encourage the growth of
cells and blood vessels
for new tissue.
And his group has applied
for funding to run
lab studies to see if the fish hosting blotchy lesions develop more subtle — and disturbing — symptoms with time, such as a slower swimming speed or changes
in blood -
cell counts.
In 1963, the couple moved to NYU to work as immunology research fellows in the lab of Baruj Benacerraf (who shared the Nobel Prize in Physiology or Medicine in 1980 for his work on the role of genetically determined, cell - surface structures in the regulation of immune reactions
In 1963, the couple moved to NYU to work as immunology research fellows
in the lab of Baruj Benacerraf (who shared the Nobel Prize in Physiology or Medicine in 1980 for his work on the role of genetically determined, cell - surface structures in the regulation of immune reactions
in the
lab of Baruj Benacerraf (who shared the Nobel Prize
in Physiology or Medicine in 1980 for his work on the role of genetically determined, cell - surface structures in the regulation of immune reactions
in Physiology or Medicine
in 1980 for his work on the role of genetically determined, cell - surface structures in the regulation of immune reactions
in 1980
for his work on the role of genetically determined,
cell - surface structures
in the regulation of immune reactions
in the regulation of immune reactions).
Tanyi and colleagues made each patient's vaccine by sifting through the patient's own peripheral blood mononuclear
cells for suitable precursor
cells, and then growing these,
in the
lab, into a large population of dendritic
cells.
Tissue engineers have been unable to grow epidermis with the functional barrier needed
for drug testing, and have been further limited
in producing an
in vitro (
lab) model
for large - scale drug screening by the number of
cells that can be grown from a single skin biopsy sample.
«Retinal nerve
cells grown
in the
lab: Work could eventually lead to
cell transplants
for people blinded by glaucoma, MS.» ScienceDaily.
To better determine the role of specific chemoattractants
in type III hypersensitivity, lead author Yoshishige Miyabe, MD, PhD, a research fellow
in Luster's
lab, used multiphoton intravital microscopy — an imaging technology pioneered
for studies of immune
cell movements
in living animals by CIID investigator and co-author Thorsten Mempel, MD, PhD — to follow
in real time the development of IC - induced arthritis
in a mouse model of rheumatoid arthritis.
«Our paper is a blueprint of how the cartilage - producing
cell, called a chondrocyte, is made and maintained by Sox9,» said He, a postdoctoral research associate in the lab of Andy McMahon, director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at
cell, called a chondrocyte, is made and maintained by Sox9,» said He, a postdoctoral research associate
in the
lab of Andy McMahon, director of the Eli and Edythe Broad Center
for Regenerative Medicine and Stem
Cell Research at
Cell Research at USC.
In this study, the team, which included Dr. Meerim Nurbaeva and Miriam Eckstein in Dr. Lacruz's lab, for the first time used freshly dissected enamel cells (ameloblasts) from rodent teeth to modulate physiological processes in order to understand the contribution of CRAC channels in enamel calcium signalin
In this study, the team, which included Dr. Meerim Nurbaeva and Miriam Eckstein
in Dr. Lacruz's lab, for the first time used freshly dissected enamel cells (ameloblasts) from rodent teeth to modulate physiological processes in order to understand the contribution of CRAC channels in enamel calcium signalin
in Dr. Lacruz's
lab,
for the first time used freshly dissected enamel
cells (ameloblasts) from rodent teeth to modulate physiological processes
in order to understand the contribution of CRAC channels in enamel calcium signalin
in order to understand the contribution of CRAC channels
in enamel calcium signalin
in enamel calcium signaling.
In a boon to stem cell research and regenerative medicine, scientists at Boston Children's Hospital, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Boston University have created a computer algorithm called CellNet as a «roadmap» for cell and tissue engineering, to ensure that cells engineered in the lab have the same favorable properties as cells in our own bodie
In a boon to stem
cell research and regenerative medicine, scientists at Boston Children's Hospital, the Wyss Institute
for Biologically Inspired Engineering at Harvard University and Boston University have created a computer algorithm called CellNet as a «roadmap»
for cell and tissue engineering, to ensure that
cells engineered
in the lab have the same favorable properties as cells in our own bodie
in the
lab have the same favorable properties as
cells in our own bodie
in our own bodies.
Recent studies
in lab animals and humans show that the much - maligned material can be a source of
cells useful
for treating a wide range of ills.
Those hoping
for quick clinical success should remember it takes time
for revolutionary treatments to go from
lab bench to bedside, says Andras Nagy, a stem
cell researcher at Mount Sinai Hospital's Lunenfeld — Tanenbaum Research Institute
in Toronto, who has not been directly involved
in Yamanaka's work.
When Kyoto University researcher Shinya Yamanaka announced
in 2006 that his
lab had created iPS
cells from mouse skin
cells for the first time, biologists were stunned.
Using next - generation sequencing technologies that were previously unavailable, Michael Gardner, a graduate research assistant, and Jianying Wang, a senior research associate
in Mitchum's
lab, made a remarkable new discovery — nematodes possess the ability to produce a second type of peptide that can effectively «take over» plant stem
cells that are used to create vital pathways
for the delivery of nutrients throughout the plant.
We hope this leads to the ability to design, study and test new therapies
for every patient on their own
cells in the
lab, leading to new treatments and breakthroughs
in personalized medicine
for individuals with a variety of lung diseases, including cystic fibrosis,» explained lead author Katherine McCauley, a PhD student at BUSM.
In an advance that could lead to new fertility treatments, researchers have coaxed immature human egg cells to fully develop in the lab for the first tim
In an advance that could lead to new fertility treatments, researchers have coaxed immature human egg
cells to fully develop
in the lab for the first tim
in the
lab for the first time.
Scientists want to be able to clone early human embryos, using
cells from patients with various diseases, so they can study the diseases
in the
lab and develop new treatments
for them.
Gabriela Cabral, a PhD student
in the
lab of Alex Dammermann at the Center
for Molecular Biology of the University of Vienna, explains: «Many people thought that centrioles are held together by the same glue as chromosomes, a substance called cohesin, which is destroyed during
cell division.
Researcher Laura S. Shankman, a PhD student
in the Owens
lab, was able to overcome the limitations of the traditional methodology
for detecting smooth muscle
cells in the plaque.
In the lab, the antibiotics had no harmful effect on normal cells, and since they are already approved for use in humans, trials of new treatments should be simpler than with new drugs — saving time and mone
In the
lab, the antibiotics had no harmful effect on normal
cells, and since they are already approved
for use
in humans, trials of new treatments should be simpler than with new drugs — saving time and mone
in humans, trials of new treatments should be simpler than with new drugs — saving time and money.
For the purpose of additional experiments, the researchers generated myocardial
cells from embryonic stem
cells and human skin
cells,
in collaboration with the
lab headed by Prof Dr Jürgen Hescheler at the University of Cologne.
They tested these drugs one at a time
for lethal interaction with 112 different tumor - suppressor gene mutations
in human cancer
cells growing
in the
lab.
Co-first author Alice Eunjung Lee, PhD, from the
lab of Peter Park, PhD, at the Center
for Biomedical Informatics at Harvard Medical School, developed the study's retrotransposon analysis tool, which detects somatic retrotransposon mutations
in single -
cell sequencing data.
The team, headed by biologist Miodrag Stojkovic, who has
labs at the Principe Felipe Research Centre
in Valencia, Spain, and at a company called Sintocell
in Serbia, obtained 161 embryos that had been donated
for research at the University of Newcastle
in the U.K. Of these, thirteen had stopped developing at 6 to 7 days after fertilization, when they were at the 16 - 24
cell stage, and 119 had stopped developing a few days after fertilization.
«First we established an efficient method
for culturing dinoflagellate
cells in our
lab,» said Shinichiro Maruyama, an assistant professor at Tohoku University.
As with the other self - diagnosis tools, home use of Ozcan's
cell phone blood imager is a ways off, but it is already being looked at
for pilot programs
in remote locations where doctors and
lab equipment are
in short supply.
«There have been previous reports of other
labs deriving beta
cell types from stem
cells, no other group has produced mature beta
cells as suitable
for use
in patients,» he said.
Now —
in a paper published online April 17, 2018
in Cell Reports — Bandyopadhyay's
lab has systematically mapped connections between 625 breast and ovarian cancer genes and nearly every FDA approved chemotherapy
for breast or ovarian cancer.
The
lab of co-author Dr. Robert Bast Jr., an expert
in ovarian cancer and vice president
for translational research at MD Anderson, inserted gel - bound carbon nanotubes into the ovaries of rodents to mimic the accumulations that are expected
for nanotubes linked to special antibodies that recognize tumor
cells.
But despite these two tracks being completely separate, two recent rounds of interviews
for clients on either side of this divide helped me recognize what a successful Indian plant breeder has
in common with an equally first - rate American
cell biologist: The passion they have
for what they do still drives their career success a decade after leaving the academic
lab.