When Liesman infected human airway
cells in the lab with this re-engineered virus, she saw infected cells ball up and puff out of the airway epithelium.
Not exact matches
In biologist John March's
lab at Cornell, for example, they have armed probiotic bacteria
with tools to make an intestinal
cell act like more like a pancreatic
cell.
Now
in 2018, I don't want to project that everything was negative
in 2017: we've seen such individuals as Nimrod May from Sirin
Labs, individuals like Mikhail Mironov from ICORating, who are having one of the most successful ICOs of 2017, and now is coming out
with one of the first
cell phones that has an encrypted wallet included on an Android platform, which I think a phenomenal piece of technology moving forward.
So why is it that
with all of our science and technology we are unable to create even the simplest
cell in the
lab under the perfect conditions?
02 Feb 2018 — Clean meat innovators Memphis Meats has been getting a lot of attention from investors recently
with billionaire businessmen Richard Branson and Bill Gates staking their claim
in the pioneering company last year — and now the venture capital arm of Tyson Foods has invested
in the food tech startup which
lab - grows meat directly from animal
cells.
The audience roars
with laughter as Polish tells how he initiated select new members into the
cell biology
lab he worked
in after college
with strategically placed miniature dry - ice bombs fabricated from plastic Eppendorf test tubes.
The
lab that I work
in is primarily interested
in understanding how and why certain cancers are more likely to spread to the skeleton, and my personal project has focused on uncovering new mechanisms that the cancer
cells use to communicate
with other
cells in the bone.
It didn't take her long to decide that she missed
lab work;
in 1985 she joined IFR
with an
in - house fellowship, investigating how gut epithelial
cells interact
with microbes.
Shukla and colleagues discovered that a small drug molecule called BX795, which is sold to
labs for use
in experiments, helped clear HSV - 1 infection
in cultured human corneal
cells,
in donated human corneas, and
in the corneas of mice infected
with HSV - 1.
Cells inside the brains contract, while cells on the outside grow and push outward, researchers at the Weizmann Institute of Science in Rehovot, Israel, discovered from working with the lab - grown brains, or organ
Cells inside the brains contract, while
cells on the outside grow and push outward, researchers at the Weizmann Institute of Science in Rehovot, Israel, discovered from working with the lab - grown brains, or organ
cells on the outside grow and push outward, researchers at the Weizmann Institute of Science
in Rehovot, Israel, discovered from working
with the
lab - grown brains, or organoids.
They found high levels of the regulatory T -
cells in patients treated
with post-transplant cyclophosphamide, and
lab - cultured
cells survived cyclophosphamide treatment.
Beginning
in the 1970s, physicians learned how to harvest skin stem
cells from a patient
with extensive burn wounds, grow them
in the laboratory, then apply the
lab - grown tissue to close and protect a patient's wounds.
«I'm working
with Professor Richard Oreffo and Dr Rahul Tare from the University's Centre for Human Development, Stem
Cells and Regeneration who are trying to create and grow cartilage in the lab using a patients» own (autologous) stem cells to then be implanted back into the patient if they have a cartilage defect,» she expl
Cells and Regeneration who are trying to create and grow cartilage
in the
lab using a patients» own (autologous) stem
cells to then be implanted back into the patient if they have a cartilage defect,» she expl
cells to then be implanted back into the patient if they have a cartilage defect,» she explains.
The NB activity
in Alberta is far ranging,
with such research as self - assembled nanostructures (M. J. Brett), single -
cell cancer analysis (L. M. Pilarski), computational modeling (D. Wishart), micro-total analysis systems or
lab on a chip (D. J. Harrison),
cell identification and manipulation (K. Kaler), and microsystems and medical diagnostics (Backhouse).
One
lab test showed a single
cell moving a distance three times its diameter and joining
with a small cancerous cluster
in just four hours.
For example, animal studies have shown that neurons derived
in the
lab from human embryonic stem
cells improve Parkinson's symptoms; however, any residual stem
cells associated
with those neurons could form masses of unwanted
cells.
By hitting breast cancer
cells with a targeted therapeutic immediately after chemotherapy, researchers from Brigham and Women's Hospital (BWH) were able to target cancer
cells during a transitional stage when they were most vulnerable, killing
cells and shrinking tumors
in the
lab and
in pre-clinical models.
In addition, the substance used to stick cells together (ViaGlue), will provide researchers with tools to create and test 3D in vitro cardiac tissue in their own labs to study heart disease and issues with transplantatio
In addition, the substance used to stick
cells together (ViaGlue), will provide researchers
with tools to create and test 3D
in vitro cardiac tissue in their own labs to study heart disease and issues with transplantatio
in vitro cardiac tissue
in their own labs to study heart disease and issues with transplantatio
in their own
labs to study heart disease and issues
with transplantation.
Next, the team tested the GD2 CAR - T
cells in mice whose brainstem was implanted
with human DIPG tumors, an experimental system that Monje's
lab pioneered.
So far, researchers have mostly turned on genes
with CRISPRa
in cells growing
in lab dishes, says Charles Gersbach, a biomedical engineer at Duke University not involved
in the new study.
This year those breakthroughs include tools for reprogramming living
cells and rendering
lab animals transparent; ways of powering electronics
with sound waves and saliva; smartphone screens that correct for the flaws
in your vision; Lego - like atomic structures that could produce major advances
in superconductivity research; and others.
However, along
with this seemingly linear storyline
in which retinoids block progesterone's promotion of CK5 +
cells, previous work
in the
lab of CU Cancer Center investigator Peter Kabos, MD, and others shows that breast cancers treated
with anti-estrogen drugs like tamoxifen or aromatase inhibitors show an increased population of CK5 +
cells — it is as if these therapies remove the roadblock of estrogen - dependent
cells, leaving CK5 +
cells to proliferate.
During that year, and subsequent years spent as a postdoc
in Morata's
lab (and later
with Konrad Basler at the University of Zurich, Switzerland), Moreno was able to link the previously isolated phenomenon of
cell competition to the well - established process of programmed
cell death.
Rahul Palchaudhuri, a postdoctoral fellow
in Scadden's
lab and first author on the paper, armed CD45 - targeting antibodies
with a payload that destroys only existing blood
cells.
That would be getting close to the number of
cells in a mouse brain,» raising the distant prospect of a human brain organoid
with cognitive and even emotional capacities, all while sitting
in a
lab dish.
Altogether, about 92 % of the «dirtied» mice survived the flu, compared
with just 17 % of «clean»
lab mice, the researchers report today
in Cell.
Researchers
in the Rice
lab of chemist and bioengineer Jeffrey Hartgerink had just such an experience
with the hydrogels they developed as a synthetic scaffold to deliver drugs and encourage the growth of
cells and blood vessels for new tissue.
The research was conducted
in the
lab of Dr. Ravid Straussman of the Weizmann Institute of Science's Molecular
Cell Biology Department, led by his graduate student Leore Geller and conducted
in collaboration
with Dr. Todd Golub and Dr. Michal Barzily - Rokini of the Broad Institute of the Massachusetts Institute of Technology.
Shobhana Natarajan, who has worked
in labs in India and was most recently a postdoc at the Department of
Cell Biology, University of Texas, Southwestern Medical Center,
in Dallas notes that
in general, resources are more limited
in India compared
with the United States.
And his group has applied for funding to run
lab studies to see if the fish hosting blotchy lesions develop more subtle — and disturbing — symptoms
with time, such as a slower swimming speed or changes
in blood -
cell counts.
In the lab, the team mixed each strain of K. veneficum with a species of algae on which it preys, and recorded the three - dimensional motions of thousands of cells using a high - speed holographic microscopy technique they described in 2007
In the
lab, the team mixed each strain of K. veneficum
with a species of algae on which it preys, and recorded the three - dimensional motions of thousands of
cells using a high - speed holographic microscopy technique they described
in 2007
in 20071.
Neurobiologist Ulo Langel of Stockholm University
in Sweden,
with colleagues at several other
labs, solved this problem by pairing PNAs
with fragments from two other proteins — transportan or pAntp — that use an unidentified mechanism to slip easily into
cells.
New findings published
in the Proceedings of the National Academy of Sciences showed
in lab studies that supplementing an epigenetic cancer drug called decitabine
with vitamin C enhanced the drug's ability to impede cancer
cell growth and trigger cellular self - destruction
in cancer
cell lines.
Even then,
with a completely clean
lab highly focused on meticulous technique, a new contamination struck
in 2013 — something Myers identified when several different
cell lines showed up
with exactly the same mutation.
In studies with human fibroblasts that make up connective tissue, Boger's team tested whether NOD1 activity could affect CMV replication in cultures of cells grown in the la
In studies
with human fibroblasts that make up connective tissue, Boger's team tested whether NOD1 activity could affect CMV replication
in cultures of cells grown in the la
in cultures of
cells grown
in the la
in the
lab.
Tissue engineers have been unable to grow epidermis
with the functional barrier needed for drug testing, and have been further limited
in producing an
in vitro (
lab) model for large - scale drug screening by the number of
cells that can be grown from a single skin biopsy sample.
Other groups are experimenting
with taking such tissue from the nose, growing it
in the
lab to isolate the desired
cells and transplanting them.
Zheng, together
with Leah Boyer, then a researcher
in Gage's
lab and now director of Salk's Stem
Cell Core, generated diseased neurons by taking skin
cells from patients
with Leigh syndrome, reprogramming them into stem
cells in culture and then coaxing them to develop into brain
cells in a dish.
Mouse brain nerve
cells (green) making a disease - causing version of the tau protein were grown
in lab dishes
with supporting brain
cells called glia.
The researchers found that the protein, called VRC07 - αCD3, triggered the activation and killing of latently HIV - infected helper T
cells when the
cells were taken from patients on antiretroviral therapy and then incubated
in the
lab with the patients» own killer T
cells.
Like many graduates, Seno spent a couple of years working
in an academic
lab after he graduated from Purdue University
with a degree
in cell biology
in 1998.
In collaboration with Ding, the lab of Olivier Voinnet at the Swiss Federal Institute of Technology in Zurich also reported in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viru
In collaboration
with Ding, the
lab of Olivier Voinnet at the Swiss Federal Institute of Technology
in Zurich also reported in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viru
in Zurich also reported
in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viru
in an accompanying paper the detection of viral siRNAs
in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viru
in cultured mouse embryonic stem
cells infected by the Encephalomyocarditis virus.
The disease model, described
in a new study by a UC San Francisco - led team, involves taking skin
cells from patients
with the bone disease, reprogramming them
in a
lab dish to their embryonic state, and deriving stem
cells from them.
David Macauley, the CEO of Virgin Health Bank QSTP, cited the encouraging example last November of a woman
in Spain whose diseased windpipe was replaced
with one grown
in the
lab from her own
cells.
In the current issue of Cell, Jing Liu, a graduate student researcher in the Chien lab at UMass Amherst working with the Laub lab at MIT, show that in the bacteria Caulobacter, a particular enzyme, Lon, can help defend against the effects of stress by cutting up and destroying small amounts of misfolded protein
In the current issue of
Cell, Jing Liu, a graduate student researcher
in the Chien lab at UMass Amherst working with the Laub lab at MIT, show that in the bacteria Caulobacter, a particular enzyme, Lon, can help defend against the effects of stress by cutting up and destroying small amounts of misfolded protein
in the Chien
lab at UMass Amherst working
with the Laub
lab at MIT, show that
in the bacteria Caulobacter, a particular enzyme, Lon, can help defend against the effects of stress by cutting up and destroying small amounts of misfolded protein
in the bacteria Caulobacter, a particular enzyme, Lon, can help defend against the effects of stress by cutting up and destroying small amounts of misfolded proteins.
Xu and colleagues grew S. gallolyticus
in lab dishes
with several different types of human
cells.
Photo of a living Brainbow zebrafish, taken by Zachary Tobias (a research technician
in Weissman - Unni's
lab), showing a brightly labeled neuron
with its
cell body (white) at bottom.
We hope this leads to the ability to design, study and test new therapies for every patient on their own
cells in the
lab, leading to new treatments and breakthroughs
in personalized medicine for individuals
with a variety of lung diseases, including cystic fibrosis,» explained lead author Katherine McCauley, a PhD student at BUSM.
Scientists want to be able to clone early human embryos, using
cells from patients
with various diseases, so they can study the diseases
in the
lab and develop new treatments for them.
According to his unpublished findings, when he puts glioblastoma
cells from patients into
lab dishes
with brain organoids, the
cells attach to the surface of the organoids, burrow into them, and within 24 to 48 hours grow into a mass that eventually «looks exactly like what happened
in the patient's own brain,» Fine said.