Sentences with phrase «cells in the pancreas into»

A new study by researchers at Sanford - Burnham Medical Research Institute (Sanford - Burnham) has found that a peptide called caerulein can convert existing cells in the pancreas into those cells destroyed in type 1 diabetes insulin - producing beta cells.

Not exact matches

Then they would inject human stem cells into the pig embryo in hopes that the human stem cells would bridge the gaps of the missing pancreas gene and form a human pancreas.

The cells, taken from the brain via the nose, have been coaxed into becoming insulin factories in the rat pancreas

«Our conclusion is that by pushing the mice into an extreme state and then bringing them back — by starving them and then feeding them again — the cells in the pancreas are triggered to use some kind of developmental reprogramming that rebuilds the part of the organ that's no longer functioning,» says senior author Valter Longo of the University of Southern California School of Gerontology and Director of the USC Longevity Institute.

Four years ago, the research team of Pedro Herrera (University of Geneva) first cast doubt on this assumption when they demonstrated that a few alpha cells in the pancreas of genetically modified diabetic mice changed into beta cells.

A chemical produced in the pancreas that prevented and even reversed Type 1 diabetes in mice had the same effect on human beta cells transplanted into mice, new research has found.

In those mice, but not in normal mice, they found that caerulein caused existing alpha cells in the pancreas to differentiate into insulin - producing beta cellIn those mice, but not in normal mice, they found that caerulein caused existing alpha cells in the pancreas to differentiate into insulin - producing beta cellin normal mice, they found that caerulein caused existing alpha cells in the pancreas to differentiate into insulin - producing beta cellin the pancreas to differentiate into insulin - producing beta cells.

Now, researchers have discovered that non-beta cells in the pancreas can be transformed into insulin - producing cells, merely by exposing them to a growth factor called BMP - 7.

In «Diabetic rats cured with their own stem cells ``, we report how researchers cured diabetic rats by turning brain stem cells extracted through the nose into insulin - producing cells in the pancreaIn «Diabetic rats cured with their own stem cells ``, we report how researchers cured diabetic rats by turning brain stem cells extracted through the nose into insulin - producing cells in the pancreain the pancreas.

In previous studies, researchers have successfully differentiated stem cells into heart, liver, pancreas or nerve cells by adding certain chemicals, but kidney cells have proved challenging.

Melton's ultimate goal is to discover how embryonic stem cells grow into special cells called islets in the pancreas.

Medicines used to treat diabetes fall into four groups: those that stimulate the pancreas to put out more insulin; those that lower insulin resistance in cells; those that help the body use insulin; and those that slow down or block the breakdown of starches, which in turn keeps blood - glucose levels lower.

In type 1 diabetes, the pancreas stops making insulin, the hormone that facilitates absorption of glucose from the blood into cells.

The work, funded by national charity Pancreatic Cancer Research Fund, uncovers new evidence that PAK4 plays a key role in enabling cancer cells to grow and to spread from the pancreas into other areas of the body, a process called metastasis.

Douglas Melton, codirector of the Harvard Stem Cell Institute in Cambridge, Massachusetts, and his colleagues study both the stem cells that develop into the pancreas and its insulin - producing cells and the genes that guide those cells» development.

Furthermore, the normal ductal cells that are able to develop into pancreatic cancer represent about 10 percent of the cells in the pancreas, complicating efforts to pinpoint the changes that occur as the tumor develops.

Gobbling a slice of sweet pumpkin pie, for instance, causes beta cells in the pancreas to secrete insulin, a hormone that allows the uptake of glucose and most amino acids into the tissues.

When they briefly exposed nestin - positive cells to a growth factor, the cells differentiated not only into neural cells but also into clusters that resemble the insulin - producing islets in the pancreas.

A ONE - OFF treatment for diabetes is a step closer thanks to a better understanding of how human liver cells can be transformed into something like the beta cells that produce insulin in a healthy pancreas.

«In type 2 diabetes, glucose does not enter the cells and increased levels of insulin, resulting from an overburdened pancreas, do nothing to facilitate glucose entry into cells for producing energy,» Martins - Green said.

But before glucose can be tapped, it must be ushered into cells with the help of insulin, a hormone produced in the pancreas.

On Wednesday, scientists reported in Nature that they had created mouse - rat chimeras — also starting with mouse pluripotent stem cells and fertilized rat eggs — in which the pancreases were sufficiently mouse - like that, when cells from them were transplanted into mice with diabetes, they churned out insulin and reversed the disease.

«This data allows classification of all human protein - coding genes into those coding for house - hold functions (present in all cells) and those that are tissue - specific genes with highly specialized expression in particular organs and tissues, such as kidney, liver, brain, heart, pancreas.

In this method, skin cells are turned directly into brain, heart, liver, or pancreas cells without going through a stem cell stage first.

In a study published in October 2008, Melton showed that it was possible to take an exocrine cell in the pancreas of a live mouse and turn it into an insulin - producing beta cell without first going back to an undifferentiated iPS statIn a study published in October 2008, Melton showed that it was possible to take an exocrine cell in the pancreas of a live mouse and turn it into an insulin - producing beta cell without first going back to an undifferentiated iPS statin October 2008, Melton showed that it was possible to take an exocrine cell in the pancreas of a live mouse and turn it into an insulin - producing beta cell without first going back to an undifferentiated iPS statin the pancreas of a live mouse and turn it into an insulin - producing beta cell without first going back to an undifferentiated iPS state.

Endoderm cells are a type of cell found in the early embryo, and which eventually mature into the body's major organs — including the pancreas, the home of β - cells.

Endoderm cells are a type of cell found in the early embryo, and which eventually mature into the body's major organs — including the pancreas, the home of ß - cells.

Human skin cells have also been directly converted into neurons that can be used to study and find treatments for diseases in the brain, as well as liver cells and insulin - producing cells of the pancreas.

In theory, an understanding of how cells go back to a previous state in their development might one day lead to a drug that could trigger a process whereby a pancreas cell exposed to the compound might return to being a stem cell and then transform into a cell that produces insuliIn theory, an understanding of how cells go back to a previous state in their development might one day lead to a drug that could trigger a process whereby a pancreas cell exposed to the compound might return to being a stem cell and then transform into a cell that produces insuliin their development might one day lead to a drug that could trigger a process whereby a pancreas cell exposed to the compound might return to being a stem cell and then transform into a cell that produces insulin.

The glucose, like all of the nutrients, soon gets absorbed into the bloodstream creating a peak in what we call «blood sugar levels», which results with the releasing of more insulin from the pancreas in order to push glucose to the cells, basically «commanding» the cells to open up and absorb it, where it gets used as an energy source.

It helps regenerate beta cells in the pancreas, which secrete insulin in order to take up sugar into the cells for energy.

Insulin is a hormone made and released into the blood by the pancreas, and its job is to shuttle nutrients (and glucose in particular) into cells for use.

Insulin is a hormone created by the pancreas, which must be present in order for glucose to get into our cells (used by the body as food).

Your pancreas releases the hormone Insulin, which takes the excess glucose and (1) puts it in needy muscle cells, or (2) puts in empty liver cells, or (3) takes all the leftovers and remakes the glucose into TRIGLYCERIDES.

When blood sugar increases, the pancreas bumps up its secretion of insulin in order to bump up the movement of glucose out of the blood stream and into the cells.

Scientific theories consider that the entrance of food antigens into the systemic body through the tight junctions may cause an auto - immune reaction against the beta cells in the pancreas.

Insulin is a hormone secreted by the beta cells of the pancreas into the bloodstream in response to the ingestion of food.

In response to climbing blood sugar, your body produces insulin from the pancreas, which then puts the blood sugar into your cells.

Elevated blood sugar also places a heavy burden on the beta cells of the pancreas to produce high amounts of insulin in an attempt to shuttle the sugar into the body's cells.

So the liver starts trying to offload the fat by dumping it back into the bloodstream in the form of something called VLDL, and that starts building up in the cells of the pancreas that produce the insulin in the first place.

In a healthy individual, the pancreas secretes insulin into the bloodstream where it then transfers glucose into your cells.

Insulin, a hormone made by the beta cells in the pancreas, is vital in order to turn food particles into glucose that can be absorbed by the bloodstream.

This occurs in a number of ways, including reduction of glucose absorption, slowing down of carbohydrate digestion, stimulating the pancreas to produce more insulin, and stimulating insulin receptors so that more sugar flows out of our bloodstream and into our cells.

Obesity leads to insulin resistance, and our blood sugars start to go up, so our pancreas starts pumping out more insulin to try to force more sugar into our muscles, and eventually the fat spills over into the pancreas as well, killing off the insulin - producing cells, and we've got diabetes — in which case we may have to start injecting insulin at high levels to overcome the insulin resistance, and these high insulin levels promote cancer.

This signals the beta cells in your pancreas to release insulin into the bloodstream.

This insulin resistance then requires the pancreas to secrete more and more insulin to overcome this resistance which leads to higher and higher insulin levels which leads to more and more deposition of fat into fat cells resulting in obesity as well as metabolic syndrome which entails diabetes, hypertension, and vascular disease, ie heart disease and strokes.

When you reach your Personal Fat Threshold, your body can no longer force excess energy into storage in your fat cells and it gets stuffed into other places that are more sensitive like your liver, your brain, your heart, your pancreas.

Insulin, which is produced by «beta cells» in the pancreas, helps in the process of moving glucose into the cells of the body where it is converted into fuel.

Insulin, a hormone produced in the pancreas, is responsible for regulating the flow of glucose from the bloodstream into the cells of the body.