Sentences with phrase «cells in tissue grafts»

Studies have shown that the clinical success of transplantation depends on the number and percentage of limbal stem cells in tissue grafts.

Not exact matches

In one such approach, researchers surgically remove brain cells, use viruses to transfer genes to the cells, and then graft them back into the animal's brain tissue.

In tests on human breast cancer cells and in special immunodeficient mice with tissue grafts, the scientists found that both agents interfered with genes involved with breast cancer cell growth, resulting in more cancer cellIn tests on human breast cancer cells and in special immunodeficient mice with tissue grafts, the scientists found that both agents interfered with genes involved with breast cancer cell growth, resulting in more cancer cellin special immunodeficient mice with tissue grafts, the scientists found that both agents interfered with genes involved with breast cancer cell growth, resulting in more cancer cellin more cancer cells.

Now, in a study recently published in the journal PLOS ONE, a team of scientists from VCU Massey Cancer Center have shown a genetic relationship between the reactivation of hCMV and the onset of graft - versus - host disease (GVHD), a potentially deadly condition in which the immune system attacks healthy tissue following a bone marrow or stem cell transplant.

The team seeded pig intestine grafts with adult stem cells taken from fat tissue in rats.

Human egg cells behaved the same way; when human ovary tissue was grafted into mice injected with PAH, the eggs died, the team reports in Nature Genetics online this month.

In addition to growing new skin for burn victims, cells from hair follicles could potentially be used to engineer vascular grafts and possibly regenerate cardiac tissues for patients with heart problems.

ASCs isolated from the stromal vascular fraction of fat have advantages over other mesenchymal stem cell sources; they are easy to isolate and expand and aid in the repair of damaged tissues [7], including islet graft survival and revascularization [8].

Creation of a rich subcutaneous vascular network with implanted adipose tissue - derived stromal cells and adipose tissue enhances subcutaneous grafting of islets in diabetic mice.

The favorable results are due in large part to the advances in managing severe graft versus host disease (GVHD), an attack on the patient's normal tissues by immune cells of the donor.

Transplanted organs, tissues and cells are targets of the host immune response, that, in the absence of adequate immunesuppression, lead to graft loss.

These grafts showed preservation of the muscle architecture and lack of mononuclear cell infiltration in the syngeneic and tolerant grafts, but massive tissue destruction in the acutely rejected control grafts.

Professional Duties & Responsibilities Biomedical and biotechnology engineer with background in design of biomaterials, biosensors, drug delivery devices, microfrabrication, and tissue engineering Working knowledge of direct cell writing and rapid prototyping Experience fabricating nanocomposite hydrogel scaffolds Proficient in material analysis, mechanical, biochemical, and morphological testing of synthetic and biological materials Extensive experience in bio-imaging processes and procedures Specialized in mammalian, microbial, and viral cell culture Working knowledge of lab techniques and instruments including electrophoresis, chromatography, microscopy, spectroscopy, PCR, Flow cytometery, protein assay, DNA isolation techniques, polymer synthesis and characterization, and synthetic fiber production Developed strong knowledge of FDA, GLP, GMP, GCP, and GDP regulatory requirements Created biocompatible photocurable hydrogels for cell immobilization Formulated cell friendly prepolymer formulation Performed surface modification of nano - particle fillers to enhance their biocompatibility Evaluated cell and biomaterial interaction, cell growth, and proliferation Designed bench - top experiments and protocols to simulate in vivo situations Designed hydrogel based microfluidic prototypes for cell entrapment and cell culture utilizing computer - aided robotic dispenser Determined various mechanical, morphological, and transport properties of photocured hydrogels using Instron, FTIR, EDX, X-ray diffraction, DSC, TGA, and DMA Assessed biocompatibility of hydrogels and physiology of entrapped cells Evaluated intracellular and extracellular reactions of entrapped cells on spatial and temporal scales using optical, confocal, fluorescence, atomic force, and scanning electron microscopies Designed various biochemical assays Developed thermosensitive PET membranes for transdermal drug delivery application using Gamma radiation induced graft co-polymerization of N - isopropyl acylamide and Acrylic acid Characterized grafted co-polymer using various polymer characterization techniques Manipulated lower critical solution temperature of grafted thermosensitive co-polymer Loaded antibiotic on grafted co-polymer and determined drug release profile with temperature Determined biomechanical and biochemical properties of biological gels isolated from marine organisms Analyzed morphological and mechanical properties of metal coated yarns using SEM and Instron Performed analytical work on pharmaceutical formulations using gas and high performance liquid chromatography Performed market research and analysis for medical textile company Developed and implement comprehensive marketing and sales campaign