Sentences with phrase «cells infected with»

The other works on view are electrifying compositions inspired by cells infected with the HIV virus.

In contrast, mammary cells infected with the miR - 142 lentivirus formed disorganized structures with multiple layers of cells (Figure 6A, B).

Mammary cells infected with the miR -150-expressing lentivirus formed a hyperplastic mammary tree with extremely increased branching and thick mammary ducts (Figure 6A, C).

(C) Degree of branching and number of mammary epithelial cell layers in the mammary tissue formed by mammary cells infected with miR - 150.

Cre - DOG is also suitable for optogenetic studies, and since cells infected with AAV - Cre - DOG retain normal neuronal function, this system may make optogenetics in specific cell populations even easier.

Developed by Kotin et al. (37), the BEVS uses Spodoptera frugiperda (Sf9) cells infected with recombinant baculoviruses containing the vector genome, helper genes, and capsids to generate yields of 1014 — 1016 viral genomes per liter in 100 - L to 200 - L bioreactors (4, 38).

In studies of human cells infected with the HIV virus, patentiflorin A had a much more significant inhibition effect on the RT enzyme.

JJ Miranda, PhD, reported that certain drugs affect genes in tumor cells infected with the Epstein - Barr Virus.

To this end, we have developed a reporter construct that generates a fluorescent signal specifically in cells infected with dengue (DENV).

Researchers in the US have developed an optimized solid - phase microextraction method for extracting volatile organic compounds from cells infected with viruses, as a way of diagnosing viral diseases.

The genomic DNA was extracted from C8166 cells infected with SIVmac251 (32H) and digested with EcoR1.

An international research collaborative has determined that a promising anti-malarial compound tricks the immune system to rapidly destroy red blood cells infected with the malaria parasite... Read more

The genomic DNA was extracted from C8166 cells infected with SIVmac251 (32H) and digested with Sal1.

Human cord - blood T - cells infected with co-cultivation with HTLV - positive T - cell lines.

CTLs can destroy cancer cells and cells infected with viruses, fungi, or certain bacteria.

D, the same primary breast cancer cells infected with KLF4 or control lentivirus were cultured in low - attachment plates and the number of mammospheres was counted after 10 days.

Cells infected with the Plasmodium falciparum parasite, the most virulent form of malaria parasite, become stiff and sticky and become lodged in small blood vessels while the parasite is developing and so avoid the filtering action of the spleen.

A protein secreted by cells infected with dengue virus can cause dangerous leakage of fluid from blood vessels, and new research published in PLOS Pathogens supports a primary underlying mechanism: disruption of a molecular barrier that lines the vessels.

Despite initial hopes that the drugs might eradicate the virus from the body, it soon became clear that no one was cured because of stubborn reservoirs of cells infected with latent virus.

When they killed the animals a week later, they found that the virus had broken apart dystrophin in their hearts and that the membranes of heart cells infected with Coxsackie B virus were more permeable to blue dye than uninfected cells.

By stymieing three genes in cells infected with HIV, researchers stop the virus from spreading to other cells

In July labs at the University of California at San Francisco, University of Massachusetts Medical School, and MIT reported that they had used RNA - interference to arrest viral replication in cells infected with HIV and polio.

T cell — stimulating vaccines may lead to the destruction of cells infected with HIV, preventing them from reproducing.

Hider and his team are developing antimalarials that can be taken by mouth and target only those red blood cells infected with parasites.

Shukla and colleagues looked at human corneal cells infected with HSV - 1 and saw that an enzyme called heparanase became significantly upregulated and activated in cells just after infection, and remained upregulated well after the initial infection.

Professor Spano explained: «Dormant CD4 T cells infected with HIV are not actively producing HIV: they are latently infected.

Cells infected with Toxoplasma don't show a ruffling membrane or any other signs of having swallowed a parasite.

He found that red ginseng extract improves the survival of human lung epithelial cells infected with influenza virus.

Any mouse cells infected with the virus would produce both viral proteins and egg proteins, thus arousing antibodies that would attack proteins on the mouse eggs.

They have evidence that some people may be able to resist infection because previous exposure to tiny amounts of virus has stimulated a strong response from killer T cells which can destroy cells infected with virus.

LOCKED IN Red blood cells infected with malaria - causing parasites (shown almost completely filling a cell) may avoid imminent destruction if new research pans out.

They found that indeed, they do, and that stimulating these cells led them to kill cells infected with HIV - 1 derived from latently infected cells, both in culture and in mice engineered to have a human immune system.

While the PIV - infected epithelial cells retained their natural elongated, columnar shape, the same cells infected with RSV balled up and puffed out of the airway epithelium, causing the infected cells to accumulate in the lumen of the airway.

The researchers also found that treating the mice with a molecule called CTL - associated antigen - 4 immunoglobulin (CTLA4Ig) suppressed damage to liver cells infected with hepatitis B virus, suggesting that this might be a potential approach to treatment.

University of Melbourne Professor, Leann Tilley, an Australian Research Council Laureate Fellow at the Bio21 Institute, tested the new drug in red blood cells infected with parasites and found that it was as effective at killing the artemisinin resistant parasites as it was for the sensitive parasites.

But when the researchers added higher concentrations of BX795 to cultured human corneal cells infected with HSV - 1, the infection was quickly cleared.

Using a combination of human or specially engineered mouse cells in vitro and in vivo animal models, study senior investigator Judy Lieberman, MD, PhD; study lead investigator Farokh Dotiwala, PhD, with a team lead by the Brazilian parasitologist Ricardo Gazzinelli, DSc, DVM, found that when an immune killer cell, such as a T - cell or natural killer (NK) cell, encounters a cell infected with any of three intracellular parasites (Trypanosoma cruzi, Toxoplasma gondii or Leishmania major), it releases three proteins that together kill both the parasite and the infected cell:

«This allowed us to examine the interactions of the florescent integrase under the light microscope both in vitro in a single HIV virion as well as in a human cell infected with it.»

Not exact matches

Researchers at California's Scripps Research Institute have been able to replace HIV infected cells with healthy cells.

Jason Mills, a gastrointestinal pathologist at Washington University School of Medicine in St. Louis, envisions growing thousands of such organoids, each from a different person's cells, and infecting them with a pathogen to study the role of individual genetics.

Shukla and colleagues discovered that a small drug molecule called BX795, which is sold to labs for use in experiments, helped clear HSV - 1 infection in cultured human corneal cells, in donated human corneas, and in the corneas of mice infected with HSV - 1.

Several physical measurements, including electron microscopy, assured us that our product was a closed loop coiled tightly around the virus - DNA template and that it was identical in size and other details with the replicative form of DNA that appears in the infected cells.

And when the team injected antibody - treated cells into mouse brains, the animals showed no symptoms at all, whereas animals injected with prion - infected, but untreated, cells died after about 160 days.

And then we infect bone marrow cells with the vector — those cells ultimately give rise to the immune system.

The researchers are beginning to use their model to test whether Zika virus, and other pathogens associated with congenital disease, can infect placental cells and / or cross the placental barrier.

Despite the presumed virulence of the strain — experiments with mouse lungs showed it produces 1000 times more bacteria in infected cells than do standard varieties — Valway says the number of TB cases that developed were kept in line with other typical outbreaks, which «shows that doing good contact investigations is important and preventative therapy works.»

«In a single mouse, for example, maybe 100 cells will be infected, which is very few compared with other viruses such as the flu.»

Here they have been infected by a herpes virus that carries a «brainbow cassette,» which makes cells express proteins that are tagged with a variety of fluorescent colors.

To address this gap in knowledge, Mirabello and Schiffman teamed up with co-senior author Robert Burk of Albert Einstein College of Medicine to sequence the whole genomes of 5,570 HPV16 - infected cell and tissue samples from women around the world and to identify associations between HPV16 genetic variants and the risk of cervical precancer and cancer.

Wherry and his collaborators used PD - 1 knockout mice infected with lymphocytic choriomeningitis virus to see whether the genetic deletion of PD - 1 would be enough to prevent T cell exhaustion.