Additional trials were excluded from consideration if their only relationship to stem
cells involved now - conventional unmanipulated bone marrow or cord blood transplants.
Not exact matches
The trial
involved an experimental checkpoint inhibitor from Bristol - Myers Squibb called ipilimumab (
now marketed as Yervoy)-- whose aim was to release the molecular brakes on her own army of T
cells.
Selected correction officers will wear body cameras through a one - year pilot program, and all staff
involved in use of force or
cell extractions will
now be required to record the events with hand - held video cameras.
Lewis is
now skimming through these genes to check their function; of those he's looked at so far, several are
involved in growth and development,
cell differentiation,
cell death, and protecting against cancer.
The team led by Andreas Plückthun, Director of the Department of Biochemistry at the University of Zurich,
involving postdoc Rastik Tamaskovic and PhD student Martin Schwill, has
now found out why these antibodies merely slow tumor growth rather than killing off the cancer
cells.
Now research in rodents suggests that gut microbes may alter the inventory of microRNAs — molecules that help keep
cells in working order by managing protein production — in brain regions
involved in controlling anxiety.
Now experiments suggest genes
involved in
cell stickiness may have given our brain its folds
The team,
involving Radha Raman Pandey and David Homolka from the Pillai lab, is
now investigating whether the piRNAs follow the same «inchworm» process within mammalian
cells, to take them a step closer to understanding the process within humans.
Now, many research advocates are wondering how Price's mix of views might play out in the new administration's approach to a wide range of issues, including funding, research
involving human embryonic stem
cells and fetal tissue, and the appointment of a new NIH director.
There are
now other methods to make stem
cells, but those made via SCNT have unique value because they are genetic copies of the living person who donated the skin
cells (other methods either use foreign
cells or
involve genetic reprogramming).
Cytokines are small proteins
involved in
cell - to -
cell interactions, whose role in triggering certain diseases is
now becoming clear.
In unpublished research, Cagan (
now at the Wellcome Trust Sanger Institute in Hinxton, England) found that genes
involved in helping neural crest
cells migrate differed between the tame and wild animals (SN: 6/13/15, p. 11).
Now, with new kinds of technologies that are coming up, new types of tissue engineering and, you know, some of the hopes that people have for stem
cells and [the] like, it may be interesting to see if there are other ways, alternatives to dealing with really badly damaged hearts that would
involve growing a new heart or replacing or repairing the damage d to a badly damaged heart that might make artificial hearts less important in the somewhat more distant future.
While previous research indicated that the cellular mechanism behind the
cell death
involved the mitochondria and lysosomes, how these two pathways converge in dopamine neurons to cause
cell death remained unknown up until
now.
This work, conducted by Yuliang Wang,
now a senior research associate at Oregon Health & Science University, uncovered intriguing differences
involving genes that affect the
cells» metabolism.
The team is
now working with doctors at Massachusetts General Hospital, who hope to use the new, noninvasive technique to study
cells involved in cancer, asthma, and other conditions in which
cell properties change as a disease progresses.
To address such obstacles, Roybal,
now an assistant professor at the University of California, San Francisco and his colleague Leonardo Morsut turned to a signaling molecule on T
cells called the Notch receptor, known to be
involved in several developmental and biological processes.
The researchers are
now looking at how ICOS signals can be altered to diminish autoimmune disorders and augmented for more effective vaccine development, and are beginning research on how ICOS signaling may benefit Chimeric Antigen Receptor - T
cell (CAR - T) therapies, which
involves engineering of patient's own immune
cells to recognize and attack their cancers.
Opponents have argued that the law should be rescinded since embryonic stem
cells can
now be generated from induced pluripotent stem
cells, a technique that does not
involve human embryos.
Now the instructions for building your brain get more complicated, since you will be rigging up the wiring that permits complex conversations
involving billions of brain
cells.
Now, a research team from Uppsala University has identified over a thousand genes that are
involved in rebuilding a fully - fledged Stentor
cell after being cut into two halves.
Now they have found that AIM is
involved in eliminating cancerized
cells.
RATS are ticklish just like us, and their reaction has
now been used to identify the brain
cells involved.
Scientists from the Max Planck Institute of Neurobiology in Martinsried have
now discovered that, in fruit flies, four classes of nerve
cell are
involved in calculating directionally selective signals.
«Our challenge
now is to tease out exactly how this protein works in the
cells involved in making up the blood - brain barrier.
Scientists
now have concrete evidence that two groups of
cells — the ventrolateral preoptic nucleus in the hypothalamus and the parafacial zone in the brain stem — are
involved in prompting SWS.
«We have identified the genes and growth factors
involved and, thanks to a collaboration with Microsoft Research, we can
now computationally model the control circuitry in mouse
cells.
Research in the lab of Edward P. Feener, Ph.D., Investigator in the Section on Vascular
Cell Biology and Director of the Proteomics Core at Joslin Diabetes Center and an Associate Professor of Medicine at Harvard Medical School,
now has shown that a substantial percentage of patients with DME do not have high levels of VEGF in the fluid inside their eyes but do have high levels of a protein called PKal (plasma kallikrein) and associated molecules that are key players in an inflammatory molecular pathway
involved in the disease.
This technique is
now being used in the lab to investigate which genes are
involved in mitotic
cell rounding and why.
But the mechanisms
involved in most diseases are inside
cells, and reaching those requires small molecules, at least for
now.
«
Now that powerful gene - editing tools, such as TALENs, are readily available, the next step is to streamline their implementation into stem
cell research,» said Dirk Hockemeyer, PhD, assistant professor of molecular and cellular biology at the University of California, Berkeley, who was not
involved in this study.
Until
now, scientists knew Esrp was
involved in how
cells interact with each other when the embryo is developing, but not the extent of that involvement.
Treatment strategies
involving neurotrophic factors are
now based on the transfer of genes, molecules or
cells into the nervous system [122].
Dorsal closure
involves three entities: the
cells that fill the gap, called amnioserosa
cells, a cable of the protein actin which runs around the gap, and the epithelial
cells that eventually stretch over and seal the gap.Until
now, scientists believed dorsal closure started when some unknown signal made the amnioserosa
cells and the actin cable contract.
Researchers from the global Human
Cell Atlas (HCA) Consortium have sequenced 250 000
cells involved in early human development and preliminary data analysis is
now underway.
The challenge takes on even more urgency with recent developments, including a federal administration
now more open to exploring the potential of stem
cells, the recent FDA approval of a human trial
involving embryonic stem
cells, as well as the reported case of a young boy who developed a brain tumor four years after receiving a stem -
cell treatment for a rare genetic disorder.
Oyer is
now a postdoc at Drexel University studying Sigma 1, a so - called «chaperone protein» that influences other proteins and pathways
involved in the amount of stress
cells endure.
The evidence against neonicotinoids
now exists in key bee brain
cells involved in learning and memory, in whole bees, entire colonies and
now at the level of whole populations of wild bees.
Realizing that hormones are only messengers
involved in
cell signaling, we can
now understand why some people have symptoms of low hormones, even when their lab tests show that their hormone levels are normal.
Studies
now show that restoring electron transport chain function by raising levels of NAD + is a rapid and efficient means of promoting the essential enzymes
involved in energy extraction and sustaining youthful
cell function.
Now is as good a time as any to mention coccidiosis, a protozoan (one -
celled) parasite that
involves both the large and small intestine as well as the liver.
Although veterinarians initially believed that the main use for stem
cells would be as replacements for damaged
cells, it is
now known that stem
cells produce anti-inflammatory substances and other compounds
involved in tissue repair.