Sentences with phrase «cells kill specific»

The researchers, working with cell cultures, first observed how individual tumour cells kill specific cells in the vascular wall, called endothelial cells.

Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim and Goethe University Frankfurt have now shown that tumour cells kill specific cells in the vascular wall.

Not exact matches

If I believed it were all ending on a specific day you could bet your bottom dollar I wouldn't waste my remaining life warning everyone... I'd be killing every last brain cell available to me and enjoying this incredible planet!

«Once this novel tumor - homing agent binds to the EphA2 receptor, the oncogene functions as a cancer - specific molecular Trojan horse for paclitaxel, carrying the drug inside the cancel cell, killing the cell, and thwarting metastasis,» said Maurizio Pellecchia, a professor of biomedical sciences at UCR's School of Medicine who led the research.

The findings inject hard facts into a debate that has long divided the medical community, with many radiation oncologists preferring adjuvant therapy — radiation given soon after prostate removal to kill off any remaining cancer cells — and many urologists preferring salvage therapy — radiation given later, when prostate - specific antigen tests suggest it's needed.

While the individual effects of the drugs on virus - specific CTL differ somewhat depending on specific assays, schedules, and doses, treatment with any of the three HDAC inhibitors impaired the ability of CTL to kill HIV - infected immune cells.

By cutting gelsolin down to a specific fragment and putting it into chemo - resistant cancer cells, the international team discovered they could make these cells susceptible to the cancer - killing effects of cisplatin.

An APC - mimetic scaffold that was engineered to activate a specific type of CAR - T cell was able to generate higher numbers of the modified T cells over longer periods of culture than analogously designed expansion beads, and the resulting cells were similarly effective in killing the lymphoma cells in the mice.

Some cell types were not killed by treatment with PAL, suggesting it could be used as a specific tumor therapy.

Over the past two years, investigators from the Perelman School of Medicine at the University of Pennsylvania have reported results from a human trial in GBM using chimeric antigen receptor (CAR) T cell therapy, through which patients» own T cells were engineered to track down and kill cancer cells that express a tumor - specific protein known as EGFRvIII.

The study, published by the journal Proceedings of the National Academy of Sciences, demonstrates that the Disney lab's compound, known as Targaprimir - 96, triggers breast cancer cells to kill themselves via programmed cell death by precisely targeting a specific RNA that ignites the cancer.

They work by sticking to specific proteins found on the surface of cancer cells, flagging them up to be killed by the immune system.

The engineered T cells also performed successfully in a mouse model of PV, killing desmoglein - specific B cells and preventing blistering and other manifestations of autoimmunity in the animals.

«We were able to show that the treatment killed all the Dsg3 - specific B cells, a proof of concept that this approach works,» Payne said.

To do this, they used T cells that can recognize and kill specific pathogens.

In a paper appearing in the journal ChemBioChem, Pentelute and colleagues showed that they could use this disarmed version of the anthrax toxin to deliver two proteins known as antibody mimics, which can kill cancer cells by disrupting specific proteins inside the cells.

Researchers from immune biology professor Annette Oxenius's group have now discovered what keeps NK cells from killing off their «colleagues from the other department» of the immune system: healthy CD8 + cells are able to detect the immune messenger substance type 1 interferon, which binds to specific receptors on the surface of these immune cells and thereby conceals their stress.

She identified that specific killing of myeloid cells represents an additional mechanism of suppression mediated by Tr1 cells, and she contributed to the definition of a new protocol for Tr1 cell induction using IL - 10 gene transfer and in the discovery of the biomarkers of Tr1 cells.

So instead of taking a shotgun approach to killing a cancer cell, we are using a targeted approach that is not necessarily specific to an anatomical site, but rather the specific mutation identified in the tumor.

ATG kills the specific cells that are attacking the bone marrow stem cells.

HIV attacks and kills a specific type of white blood cell, called a CD4 cell.

The specific antigen approach uses selected antigens that are also present in the patient's tumor so that the immune system will be educated to recognize the tumor antigen and kill tumor cells expressing the antigen.

Drug from Mediterranean Weed Kills Tumor Cells Scientists at the Johns Hopkins Kimmel Cancer Center, working with Danish researchers, have developed a novel anticancer drug designed to travel — undetected by normal cells — through the bloodstream until activated by specific cancer protCells Scientists at the Johns Hopkins Kimmel Cancer Center, working with Danish researchers, have developed a novel anticancer drug designed to travel — undetected by normal cells — through the bloodstream until activated by specific cancer protcells — through the bloodstream until activated by specific cancer proteins.

Their specialised killing abilities depend upon their cell surface receptor (T cell receptor, TCR) that recognises specific antigens expressed on their targets» cell surface.

Natural killer (NK) cells, the «rapid response» cells of the innate immune system, can kill virally infected cells and thereby slow down an infection until antigen - specific and clonally - expanded cytotoxic T cells can be recruited to finish the job.

Similar to CTLs, these CD4 T cells will be specific to a tumor antigen, but unlike CTLs, they generally can not kill antigen - bearing tumor cells.

This process activates the CD8 T cell and causes it to divide, creating millions of CTLs to kill tumor cells that bear that specific tumor antigen, including neoantigens.

We believe DCs are the most important immune cells to target because they initiate the specific immune response that generates CTLs to kill the tumor.

Thanks to I - chlor's photosensitizing property, laser light of specific wavelengths applied to a tumor containing it causes cancer cells to overheat, killing them without affecting normal cells.

A specific chemical molecule helps to break down MYCN, which either kills the cancer cell or makes it mature into a harmless neuron.

HIV attacks and kills a specific type of white blood cell, called a CD4 cell.

In fact, there are specific plant compounds that actually kill cancer cells without harming the healthy cells of the body.

They do not kill cancerous or viral cells, but regulate the action of specific genes that control the production of cellular proteins that affect cell growth.

RemedyLink Ellagic Acid contains a blend of USP grade ellagic acid and specific herbs which offer many health benefits, some of which include inhibiting fungi and yeast growth, killing bacteria, promoting the apoptosis of certain cells, and more.

The immune system is made up of a team of different types of cells that, while each having their own specific function, work together to protect the body from foreign invaders: B - cells produce antibodies; T - cells conduct surveillance for potentially dangerous molecules and kills dangerous cells such as disease - causing bacteria; and macrophages are the scavenger cells of your body acting like garbage trucks, cleaning up residue and removing potentially dangerous substances.

HOW VACCINES WORK After vaccination, the immune system is «trained» to recognize infectious agents by producing proteins called antibodies or activating specific cells to kill the agents.

In any of these forms, drugs are administered to kill remaining cancer cells after removing a tumor in surgery (adjuvant), shrink an existing tumor prior to surgery (neoadjuvant), or quicken remission for specific blood - borne cancers (induction).