Sentences with phrase «cells marker ssea»

One of these cells types, characterized by both the expression of the Venus transgene and the ES cells marker SSEA - 1 (V+S +), appears to represent an early step in primitive endoderm specification.

«We couldn't have figured out what was happening without the expertise of our collaborators at U.C. Davis, who determined the genetic sequence of every single cell marker on the cells in the lymph nodes,» says Miller.

Cells grown on hydrogels of the same stiffness all display fat cell markers and deform the underlying matrix material the same way.

The infected cells were multinucleated syncytia and expressed the S100 and p55 dendritic cell markers.

«We can direct them to CD45, a cell marker which is exclusively expressed in the blood system.

In 1988 and 1989 at Edouard Herriot Hospital, two fetuses whose blood cell markers showed they had severe immune disorders became the first ever to receive a cell transplant.

The figure in question is supposed to show patterns of expression for a range of ES cell markers in the 11 cell lines.

One common application for quantum dots is to use them as cell markers in biomedical research, says Todd Krauss, an associate professor of chemistry and optics at the University of Rochester's Institute of Optics who studies the fundamental properties of quantum dots as well as their optical properties.

«Eighty - two percent of the smooth muscle cells within advanced atherosclerotic lesions can not be identified using the typical methodology since the lesion cells down - regulate smooth muscle cell markers.

They found that ONC201 alters the gene expression of cancer stem cell markers and signaling pathways prior to killing the tumor cells, providing pharmacodynamic biomarkers of response.

A stem cell is generally characterized by the presence of various proteins — or cell markers — on its outer surface.

«If the CD117 cell population does lead to tumor initiation or cancer reoccurrence, this cell marker could become a therapeutic target,» she says.

The cancer cell marker that Johnson and her team identified was a specific change in protein glycosylation, that is, a unique pattern of sugars decorating a protein found on the cell surface.

«You have blood drawn and that one blood sample can be tested for a comprehensive array of cancer cell markers.

Coxsackie B virus (red) infects cells positive for the heart stem cell marker Sca - 1 (green).

They found that cells treated with FGF2 expressed late Purkinje - cell markers and developed structures characteristic of those cells.

At one end of the neuroepithelium, a region developed that was positive for markers of progenitors of granule and deep cerebellar nuclei projection neurons and negative for Purkinje - cell markers, and whose origins could be traced to the rhombic lip zone of the cerebellar plate.

A T - cell marker panel that can identify subsets of tumor - associated T - cells allows scientists to identify and target subpopulations of T - cells playing unique roles in the immune response against a tumor.

However, we have found a fluorescent marker for nestin, a neural crest stem cell marker, in the posterior limbal region of the human anterior segment in the vicinity of both the trabecular meshwork and Schwalbe's line (unpublished).

The ECETOC Young Scientist Award at the European Societies of Toxicology (Eurotox) Annual Congress (Rhodes, Greece, 5 - 8 October 2008) went to: Ms Nathalie Lambrecht of CARDAM VITO in Belgium for her poster, entitled «Pathway analysis of dendritic cell markers for skin sensitization.»

To verify that the individual cells they picked were pure, the researchers cultured them for several days to determine, using cell markers, whether they formed mature HSCs.

Methods: Human corneas with attached scleral rims were obtained from eye banks and were assayed for telomerase activity and BrdU (bromodeoxyridine) incorporation to determine, respectively, the presence of a stem - like cell marker and replicative activity.

Perivascular cells, including pericytes in the smallest blood vessels (e.g., microvessels) and ARCs around larger ones, express mesenchymal stem cell markers and bear a multi-differentiation fate potential (differentiate into osteoblasts, chondrocytes, adipocytes, smooth muscle cells and myocytes) similar to that documented for MSCs in vitro.

Cancer stem cell markers are enriched in normal tissue adjacent to triple negative breast cancer and inversely correlated with DNA repair deficiency.

Further research uncovered a broad spectrum of cell surface stem cell markers (e.g., CD133, CD44, and CD24) that allow the identification of CSCs in human solid tumors, including brain, breast, prostate, pancreas, liver, ovary, skin, colon cancers, and melanoma (3 - 6)(Figure 1 based on 7).

There are no specific markers to identify them; however, they are negative for hematopoietic cell markers like CD34 / 45 / HLA - DR and express CD90 / 73/105 on their surface 2, 3, 4.

Human T - cell leukemia virus type I Tax induces the expression of dendritic cell markers associated with maturation and activation.

Infiltrating cells in the myocardium and skeletal muscle were positive for the T - cell marker CD3 or the macrophage marker CD68.

Corresponding to upregulated TRF2 expression at 80μM, stem cell markers like CD44 and Oct4 were also observed to be upregulated in Clonospheric HCT116 as compared to Parental HCT116 (Fig. 3a and 3b) Decreasing CD24 expression in clonospheric HCT116 was observed which correlated well with increased stem cell expression (Fig. 3b).

This gave a mixed population of cells with 20 % expressing CD34, a hematopoietic stem cell marker, with some co-expression of endothelial cell markers (CD31, Flk1, and VE - cadherin).

Solid tumours are reported to possess a sub set of cells called Side Population expressing various stem like cell markers, self - renewal capacity and ability to give rise to differentiated cells [23, 24].

Review of «In Vitro Cell Motility as a Potential Mesenchymal Stem Cell Marker for Multipotency» from Stem Cells TM by Stuart P. Atkinson

Significance of CD44 and CD24 as Cancer Stem Cell Markers: An Enduring Ambiguity.

Cell markers are helpful tools used to identify a specific immune cell population.

Title: Single - molecule transcript counting of stem - cell markers in the mouse intestine Authors: Itzkovitz S, Lyubimova A, Blat IC, Maynard M, van Es J, Lees J, Jacks T, Clevers H, van Oudenaarden A Date: 2011 Publication Details: Nat Cell Biol.

For the detection of specific antigens, the following primary antibodies were used: mouse monoclonal anti-Tuj1 (Covance, Princeton, NJ, USA) as a neuronal marker, rabbit anti-L1 (kindly provided from Dr. Asou)[52] and rat monoclonal anti-L1 (Millipore, Billerica, MA, USA) as granule cell markers, rabbit anti-calbindin D28K (Millipore) as a Purkinje cell marker, and rabbit anti-glial fibrillary acidic protein (GFAP, DAKO, Denmark) as an astrocyte marker.

This catalog offers a detailed choice of the most commonly used cell markers and an extensive selection of antibodies used in immunology.

Confocal images of P150 dystrophic retina transplanted with hNPCctx — GDNF and double stained with antibodies against human nuclear antigen (red) and either (A) recoverin, a photoreceptor and cone bipolar cell marker (green), or (B) protein kinase Cα (PKCα), a bipolar cell marker (green).

(C) Confocal image of P150 dystrophic inner retina transplanted with hNPCctx — GDNF and double stained with antibodies against nestin, a neural stem and progenitor cell marker (green) and human nuclear antigen (red).

«At first we blamed ourselves, but then we looked at the cell markers and saw that the cells were aging much faster» than true embryonic cells.

Therefore, it is necessary to determine the expression patterns of VASA and other germ cell marker genes in monkeys, but only limited information is currently available [7], [13].

Using this cell line we show that apparently undifferentiated ES cell cultures consist of at least three cell types defined by this lineage - specific low - level transcription and the expression of the ES cell markers Oct4 and Nanog.

With this reporter we split ES cell cultures into two fractions that both express certain stem cell markers but only one of which expresses low levels of an endodermal marker gene.

In addition, the expression of TEKT1, a postmeiotic male germ cell marker [53], was examined during EB development.

It will be important to include assays of NK cell markers and functions in future longitudinal studies in order to investigate this point in detail as well as to consider the trace element zinc as an essential co-factor for optimal NK cell activity.

The expression of germ cell marker genes in monkey ES cells and tissues was examined using an RT - PCR analysis.

In addition, the expression of other germ cell markers, such as NANOS and PIWIL1 genes, was also up - regulated as the EB differentiation progressed.

With regard to the meiotic germ cell markers, SCP1 and SCP3 expression was also detected in the testes, whereas MLH1 was expressed in various tissues and ES cells.

Among the early germ cell markers examined, VASA is a candidate gene for detecting pre-meiotic germ cell differentiation from monkey ES cells, because its expression is detected earlier in the primordial stage of germ cell development in comparison to that of PIWI family genes in vivo in mice and humans [11], [36]--[38], [49].

The expression of other germ cell marker genes, such as NANOS1, NANOS2, NANOS3 and PIWIL1, increased in the EBs as well.