The body's response to fetal
cells migrating to the mother's skin, can be calmed with adaptogens.
The release of inflammatory cytokines, or intercellular signaling molecules such as interleukin - 1 (IL - 1), interleukin - 2 (IL - 6), and tumor necrosis factor alpha (TNF - α) at the site of immune activation causes other immune
cells migrating throughout the lymphatic vessels of the body to express more cell adhesion molecules (CAMs).
Visual inspection of the imaging data for FTY720 - treated versus control LNs suggested that there were fewer Cxcr6GFP / + innate - like lymphocytes in the SCS after FTY720 treatment and less examples of
cells migrating into the sinus (Video 3).
Our conclusion that LFA1 and ICAM1 function during innate - like lymphocyte movement from the SCS into the LN parenchyma is based on four sets of observations in mice treated with αL blocking antibody: (1) innate - like lymphocytes transiently accumulate in the SCS; (2) the accumulated cells exhibit an unusual elongated morphology (suggesting a less adhesive state); (3) tracking analysis shows reduced numbers of
cells migrating from the SCS into the parenchyma; (4) the cells are more sensitive to dislodgement by CD169 blocking antibody.
In this article, we present a set of tools to quantify the flow dynamics of collagen contraction, induced by
cells migrating out of a multicellular cancer spheroid into a three - dimensional (3D) collagen matrix.
The pairs of collagen expressing
cells migrating toward each others until they touched at the midline.
The main role here is played by immune
cells migrating...
We have recently shown that in avian embryos, muscle formation is initiated by Delta1 - positive neural crest
cells migrating from the dorsal neural tube that, in passing, trigger NOTCH signalling and myogenesis in selected epithelial somite progenitor cells, allowing them to migrate into the nascent muscle to differentiate.
But in humans, they found a stream of
cells migrating from the telencephalon to the dorsal thalamus, a part of the diencephalon that sends information to the frontal lobes and other association areas.
The main role here is played by immune
cells migrating from the blood into the tissue to fight the inflammation.
Compared with unheated mice, the animals with the faux fever had twice as many white blood
cells migrating out of the blood vessels and into the lymph tissue that lines the skin and gut, which is where they need to be to attack incoming pathogens.
With embryonic
cells migrating as fast as several microns per second, he needed high - speed video that could capture the process.
This makes me happy: Microglia
cells migrate into tumors and supply cancer cells with a substance needed for the repair of DNA damage.
During pregnancy, baby
cells migrate through the placenta.
A few years ago, Cornelia Halin, professor at the Institute of Pharmaceutical Sciences, and her team observed that dendritic
cells migrate in a zigzag pattern within lymphatic capillaries (see ETH Life article from 09.08.2012).
Cells migrate along the electric currents, closing the scratch wound in about 48 hours.
One research group investigating this possibility followed the activity of fetal microchimeric cells in a mother rat after the maternal heart was injured: they discovered that the fetal
cells migrated to the maternal heart and differentiated into heart cells helping to repair the damage.
Neural crest
cells migrate to different parts of an embryo and give rise to several tissues including the bone and
One of the key questions in biology is to identify how tissues are repaired after trauma and understand how stem
cells migrate, proliferate, and differentiate to repair tissue damage.
Her research is identifying how blood
cells migrate between blood and bone marrow and how they multiply.
Those cells migrate throughout the embryo to form many tissues.
Those embryonic
cells migrate in the embryo and contribute to tissues involved in the fight - or - flight response, facial development and coloring.
In unpublished research, Cagan (now at the Wellcome Trust Sanger Institute in Hinxton, England) found that genes involved in helping neural crest
cells migrate differed between the tame and wild animals (SN: 6/13/15, p. 11).
In mice with pancreatic tumors, Kalbasi and other members of the team found relatively high levels of inflammatory compounds including CCL2, the signaling molecule that activates CCR2 on monocytes and macrophages to make
these cells migrate to tumors.
But recent research in mice suggested cancer
cells migrate in groups (SN: 1/10/15, p. 9).
So, Chaudhry says, a similar thing could be happening when fetal
cells migrate to the brain.
Many tumors spread: Single cancer
cells migrate with blood flow through the body before they settle in new tissue.
In contrast to other cell - movement systems in which
cells migrate along fibers or reorganize the extracellular matrix, the «hand - over-hand» pulling causes the shortening and bending of platelet - attached fibers.
During this process, the synergid cell dies and degenerates, and the sperm
cells migrate to the egg and central cell.
It is still not entirely clear whether the cancer
cells migrate directly through the resulting gap in the vascular wall or whether there is an indirect effect: «We have evidence that many more molecules are released when the vascular wall cell dies and that they render the surrounding area more permeable to cancer cells,» says Offermanns.
Antibody responses are initiated in lymph nodes close to the site of initial infection (so - called draining lymph nodes, or DLNs), where antigen - presenting cells, helper T cells, and antibody - producing B
cells migrate to and interact to form so - called «germinal centers» and produce a highly specific antibody response.
During brain development, these stem
cells migrate outward from the center region.
In humans, after a stem cell splits in two, only one of the daughter
cells migrates away and becomes a specialised cell, leaving one behind to produce more cells.
Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim, together with U.S. colleagues, have now observed in the embryo of the zebrafish that muscle
cells migrate from the undamaged atrium into the ventricle and thus significantly contribute to regeneration.
They performed a series of experiments with alginate barriers surrounded by human mammary cells, observing how
the cells migrate when the barrier is dissolved away.
Cells migrate by connecting their cytoskeleton — a network made up of proteins — to adhesion molecules which in turn get in contact with the surrounding connective tissue.
However, when these myeloid
cells migrate to tumor sites, they can differentiate to tumor associated macrophages (TAMs), which can in turn stimulate the formation of blood vessels in tumors and promote enhanced tumor cell invasion and motility.
The researchers hope to use their discovery to better understand how metastatic cancer
cells migrate into the bloodstream and spread cancer throughout the body.
The Ludwig Center at the University of Chicago --- under the direction of Ralph Weichselbaum, MD, the Daniel K. Ludwig Professor and Chair of the Department of Radiation and Cellular Oncology, and Geoffrey Greene, PhD, the Daniel K. Ludwig Professor in the Ben May Cancer Research Institute at the University of Chicago — will focus on metastasis, the process by which cancer
cells migrate from a primary tumor to multiple distant sites.
MAIT
cells migrate to the site of bacterial infection both in humans and mice.
During development,
these cells migrate with the axons that they will myelinate, and depend on those same axons for appropriate signals to survive and differentiate.
Once we had experience in treating children with brain disorders that were due to inherited metabolic conditions, we learned that when we gave cord blood
cells they migrated and engrafted in the brain on a permanent basis.
Myosin IIA deficient
cells migrate efficiently despite reduced traction forces at cell periphery.
The prize committee noted his radial unit hypothesis, which stated that in the developing cerebral cortex the cells are created at the base of each column, each new
cell migrates past its predecessors, and the related «protomap» hypothesis on external signals determining cell function as it grows and forms complex connections.
These cells migrate to the bone marrow, where they self - renew and rebuild the entire blood system.
As the primordial germ
cells migrate through the blood from the germinal crescent to the gonads they pick up the new genes.
Cooper, Jossin find surprising new role for N - cadherin; finding could shed light on how normal and cancerous
cells migrate within the body
By imaging cancer cells in vivo, we are studying how
cells migrate in and interact with complex environments in the living animal (Fig 2C).
Our goal is to determine if epithelial
cells migrate passively because of the pushing force generated by cell division in the crypts, actively using specialized cellular protrusions or if they are transported by underlying fibroblasts and basement membrane (BM).
They'd be able to study how tumor
cells migrate: how they look, how they interact with the blood system to find nourishment to grow and spread through the body.