Not exact matches
The researchers also found that arteries and veins from the macaques» hearts grew into the
new heart tissue, the first time it has been shown that blood vessels from a
host animal will grow into and nurture a large stem -
cell derived graft
of this type.
Identifying a role for tuft
cells in the interactions between the virus and its
host «is a significant step forward,» says immunologist David Artis
of Weill Cornell Medicine in
New York City, who was not involved in the study.
A
host can often be infected with more than one type
of virus and, as viruses replicate in the
host's
cells, the genetic segments
of the progeny viruses can be shuffled into
new combinations.
Her most recent paper — this one published in PNAS, the official journal
of theNational Academy
of Sciences — explains a totally
new way that viruses operate in building particles and how viruses can change shapes to interact with their
host cells.
Her studies on pseudotypes, especially between RNA and DNA viruses, demonstrate the spread
of viruses to
new host cells and provide important tools for genetic engineering.
«We also need to establish the role
of the
host epidermal
cells that the dermal papilla
cells interact with, to make the
new structures.»
Nonetheless, if a small number
of inactive chlamydia
cells passed from groom to bride, the infection could have became active in its
new host.
Lead author Elizabeth Egan, research fellow in the Department
of Immunology and Infectious Diseases at Harvard Chan and instructor in pediatrics at Boston Children's Hospital, and colleagues developed a
new technique to tap into a relatively unexplored area — identifying characteristics
of a
host red blood
cell that make it susceptible to the parasites.
Her discoveries are at the forefront
of a
new focus in microbiology: viewing the
host - pathogen relationship as a «competition for nutrients,» says
cell biologist Navdeep Chandel
of Northwestern University in Chicago.
«We've solved a mystery, revealing a
new aspect
of our innate immune system and what flu has to do to get around it,» says Nicholas Meyerson, a postdoctoral researcher in the BioFrontiers Institute and lead author
of a paper published in the Nov. 8 issue
of Cell Host and Microbe.
The
new study shows that the synthetic compound is capable
of inhibiting the activities
of several DNA - processing enzymes, including the «integrase» used by the Human Immunodeficiency Virus (HIV) to insert its genome into that
of its
host cell.
«The
new model enables studies
of the complex interactions between
host cells, mucus production, and gut microbes in a system that closely mimics the situation in human patients,» Dawson said.
The study, published October 14 by
Cell Host & Microbe, underscores the importance
of antimicrobial peptides and hints at a
new therapeutic approach to helping the immune system get a leg up on this crafty pathogen.
Because the
cells used to seed the platform can come from anyone, the
new tissues could be genetically identical to the intended
host, reducing the risk
of organ rejection.
«Given the serious threat
of graft - versus -
host disease,
new approaches to make stem
cell transplants safer for patients remain a critical unmet need,» said Dr. Leslie Kean, the trial's principal investigator and associate director
of the Ben Towne Center for Childhood Cancer Research at Seattle Children's.
The
new Wisconsin study shows that a small set
of short - chain fatty acids produced as the gut bacteria consume, metabolize and ferment nutrients from plants are important chemical messengers, communicating with the
cells of the
host through the epigenome.
A
new study describes research helping tease out the mechanics
of how the gut microbiome communicates with the
cells of its
host to switch genes on and off.
Writing online in the journal Molecular
Cell, a team
of researchers from the University
of Wisconsin - Madison describes
new research helping tease out the mechanics
of how the gut microbiome communicates with the
cells of its
host to switch genes on and off.
Following introduction into mammalian
hosts (including humans) by the bite
of a sand fly, Leishmania parasites undergo extensive changes to adapt to survival and multiplication inside the
new host cells and tissues.
In the future, these findings may form the basis for the development
of new methods for treating viral infections, as the majority
of all virus faces a similar challenge, namely to have to selectively replicate its own genetic material in competition with the genetic material
of the
host cell.
Nevertheless, they discovered that groups
of viruses that were farther from the
host cell were more mature than those closer to it, which suggested that the
host cell releases
new virus in a series
of «semi-synchronized» waves.
A
new test may reveal which patients will respond to treatment for graft versus
host disease (GVHD), an often life - threatening complication
of stem
cell transplants (SCT) used to treat leukemia and other blood disorders, according to a study led by researchers at the Icahn School
of Medicine at Mount Sinai and published online today in the journal Lancet Haematology and in print in the January issue.
Now, researchers at the University
of Missouri have shown that a
new line
of genetically modified pigs will
host transplanted
cells without the risk
of rejection.
These results, published in the scientific journal
Cell Host & Microbe, open up
new possibilities for the development
of life - saving therapies.
Cell phones
host their owners» signature set
of microbes, scientists report in a
new study published June 24 in PeerJ.
The results, revealing
new examples
of heritable bacterial species — including those related to diet preference, metabolism, and immune defense — appear May 11 in
Cell Host & Microbe's special issue on the «Genetics and Epigenetics
of Host - Microbe Interactions.»
The results
of this original study are highly relevant to other human diseases that dependent on genome instability, such as fungal infection or cancer, and open
new venues for anti-leishmanial drug discovery using
host - directed strategies that target the parasite's metabolic dependence on the
host cell, thus preventing the adaptive evolution
of drug resistant parasites.
However, this
new discovery makes it possible to safely mass - produce graphene and graphene membranes to improve a
host of products, from fuel
cells to solar
cells to supercapacitors and sensors.
Mitochondria are the descendants
of bacteria that settled down inside primordial eukaryotic
cells, eventually becoming the power plants for their
new hosts.
«These viruses are hijacking many
of the
host cell translation steps or pathways to favor the production
of new virus progeny,» says Ruggieri.
New research out
of Duke University shows that RNA viruses are littered with N6 - methyladenosine tags which affect the ability
of these viruses to infect
cells and, ultimately, their human
hosts.
The phages infiltrate bacterial
cells, where they commandeer the
host machinery to make thousands
of new phages; then they escape through the bacterial
cell wall — killing the
host — and spread to infect their next victims.
The
new imaging technique will allow researchers to see the effects
of novel drugs on this final stage in the parasite's invasion strategy, researchers report online on this week in
Cell Host & Microbe.
«Bacterial and
host cell proteins interact to regulate Chlamydia's «exit strategy»:
New research suggests major role for calcium ion signaling in release
of Chlamydia from infected
cells.»
Writing online Nov. 23 in the journal Molecular
Cell, a team
of researchers from the University
of Wisconsin — Madison describes
new research helping tease out the mechanics
of how the gut microbiome communicates with the
cells of its
host to switch genes on and off.
Instead
of using light energy to produce food to support the salamander
host, as happens in coral - algae interactions, the algae in salamander
cells struggle to adapt to their
new environment.
In the
new papers, according to STAT, scientists will report that the organoids survived for extended periods
of time — two months in one case — and even connected to lab animals» circulatory and nervous systems, transferring blood and nerve signals between the
host animal and the implanted human
cells.
New research from La Jolla Institute for Allergy and Immunology lays the groundwork to parse how the virus interacts with its
host and causes disease by pinpointing CD8 + T
cells, a subset
of T
cells more commonly known as cytotoxic or killer T
cells, as important gatekeepers that control Zika infection or limit the severity
of disease.
The information role
of DNA was further supported in 1952 when Alfred Hershey and Martha Chase demonstrated that to make
new viruses, a bacteriophage virus injected DNA, not protein, into the
host cell (see How Viruses Work for more information).
It's the death and inevitable breakdown
of these
cells that make your body look cozy to a whole
host of new bacteria.
ES
cells provide
new opportunities for developing and establishing
new treatments, including transplantation tolerance induction, because
of their unique characteristics: lack
of MHC antigens, poor expression
of co-stimulatory molecules and lack
of T
cells that can trigger graft - versus -
host reaction.
My laboratory seeks to better understand the pathological interplay
of human retroviruses like human immunodeficiency virus (HIV) and human T -
cell lymphotropic virus (HTLV) with their cellular
hosts with the goal
of providing
new approaches for prophylaxis and therapy.
Two
new NSG mouse models allow immunological dissection
of graft - versus -
host disease (GVHD) responses and in vivo testing
of therapeutic agents targeting human CD4 T
cells.
The Materials Project, a Google - like database
of material properties aimed at accelerating innovation, has released an enormous trove
of data to the public, giving scientists working on fuel
cells, photovoltaics, thermoelectrics, and a
host of other advanced materials a powerful tool to explore
new research avenues.
Through a
new study that explores one aspect
of how the virus hijacks
host cell machinery to replicate itself, UNC Lineberger Comprehensive Cancer Center researchers have gained insight into the workings
of a potential drug target for hepatitis C.
A. Bacteria: completely independent, able to eat and reproduce quickly (can develop into millions
of cells in 4 hours) B. Virus: 1/1000 smaller than a bacterial
cell, not alive, attaches to a
host cell and injects its material into that
cell and uses the genetic material to make
new viruses - the
host cell bursts and releases the viruses C. Parasites:
Once introduced into the bloodstream
of the
new host, the virus is replicated in the muscle
cells (not in the bloodstream), passing via the peripheral nervous system toward the central nervous system.
Soon the
host cell becomes a virus factory, replicating thousands
of new viral organisms to go forward and infect
new cells.
It's been said over and over again — in the news, in the
New England Journal
of Medicine, in a letter from over 40
of the nation's leading medical institutions — that fetal tissue samples are unlike any other
cell research, helping scientists find cures for a
host of diseases.
With more CD4 +
cells at the scene
of the infection, there are more
cells for HIV to target, increasing its chance
of successfully infecting a
new host.