Sentences with phrase «cells of new host»

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The researchers also found that arteries and veins from the macaques» hearts grew into the new heart tissue, the first time it has been shown that blood vessels from a host animal will grow into and nurture a large stem - cell derived graft of this type.
Identifying a role for tuft cells in the interactions between the virus and its host «is a significant step forward,» says immunologist David Artis of Weill Cornell Medicine in New York City, who was not involved in the study.
A host can often be infected with more than one type of virus and, as viruses replicate in the host's cells, the genetic segments of the progeny viruses can be shuffled into new combinations.
Her most recent paper — this one published in PNAS, the official journal of theNational Academy of Sciences — explains a totally new way that viruses operate in building particles and how viruses can change shapes to interact with their host cells.
Her studies on pseudotypes, especially between RNA and DNA viruses, demonstrate the spread of viruses to new host cells and provide important tools for genetic engineering.
«We also need to establish the role of the host epidermal cells that the dermal papilla cells interact with, to make the new structures.»
Nonetheless, if a small number of inactive chlamydia cells passed from groom to bride, the infection could have became active in its new host.
Lead author Elizabeth Egan, research fellow in the Department of Immunology and Infectious Diseases at Harvard Chan and instructor in pediatrics at Boston Children's Hospital, and colleagues developed a new technique to tap into a relatively unexplored area — identifying characteristics of a host red blood cell that make it susceptible to the parasites.
Her discoveries are at the forefront of a new focus in microbiology: viewing the host - pathogen relationship as a «competition for nutrients,» says cell biologist Navdeep Chandel of Northwestern University in Chicago.
«We've solved a mystery, revealing a new aspect of our innate immune system and what flu has to do to get around it,» says Nicholas Meyerson, a postdoctoral researcher in the BioFrontiers Institute and lead author of a paper published in the Nov. 8 issue of Cell Host and Microbe.
The new study shows that the synthetic compound is capable of inhibiting the activities of several DNA - processing enzymes, including the «integrase» used by the Human Immunodeficiency Virus (HIV) to insert its genome into that of its host cell.
«The new model enables studies of the complex interactions between host cells, mucus production, and gut microbes in a system that closely mimics the situation in human patients,» Dawson said.
The study, published October 14 by Cell Host & Microbe, underscores the importance of antimicrobial peptides and hints at a new therapeutic approach to helping the immune system get a leg up on this crafty pathogen.
Because the cells used to seed the platform can come from anyone, the new tissues could be genetically identical to the intended host, reducing the risk of organ rejection.
«Given the serious threat of graft - versus - host disease, new approaches to make stem cell transplants safer for patients remain a critical unmet need,» said Dr. Leslie Kean, the trial's principal investigator and associate director of the Ben Towne Center for Childhood Cancer Research at Seattle Children's.
The new Wisconsin study shows that a small set of short - chain fatty acids produced as the gut bacteria consume, metabolize and ferment nutrients from plants are important chemical messengers, communicating with the cells of the host through the epigenome.
A new study describes research helping tease out the mechanics of how the gut microbiome communicates with the cells of its host to switch genes on and off.
Writing online in the journal Molecular Cell, a team of researchers from the University of Wisconsin - Madison describes new research helping tease out the mechanics of how the gut microbiome communicates with the cells of its host to switch genes on and off.
Following introduction into mammalian hosts (including humans) by the bite of a sand fly, Leishmania parasites undergo extensive changes to adapt to survival and multiplication inside the new host cells and tissues.
In the future, these findings may form the basis for the development of new methods for treating viral infections, as the majority of all virus faces a similar challenge, namely to have to selectively replicate its own genetic material in competition with the genetic material of the host cell.
Nevertheless, they discovered that groups of viruses that were farther from the host cell were more mature than those closer to it, which suggested that the host cell releases new virus in a series of «semi-synchronized» waves.
A new test may reveal which patients will respond to treatment for graft versus host disease (GVHD), an often life - threatening complication of stem cell transplants (SCT) used to treat leukemia and other blood disorders, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and published online today in the journal Lancet Haematology and in print in the January issue.
Now, researchers at the University of Missouri have shown that a new line of genetically modified pigs will host transplanted cells without the risk of rejection.
These results, published in the scientific journal Cell Host & Microbe, open up new possibilities for the development of life - saving therapies.
Cell phones host their owners» signature set of microbes, scientists report in a new study published June 24 in PeerJ.
The results, revealing new examples of heritable bacterial species — including those related to diet preference, metabolism, and immune defense — appear May 11 in Cell Host & Microbe's special issue on the «Genetics and Epigenetics of Host - Microbe Interactions.»
The results of this original study are highly relevant to other human diseases that dependent on genome instability, such as fungal infection or cancer, and open new venues for anti-leishmanial drug discovery using host - directed strategies that target the parasite's metabolic dependence on the host cell, thus preventing the adaptive evolution of drug resistant parasites.
However, this new discovery makes it possible to safely mass - produce graphene and graphene membranes to improve a host of products, from fuel cells to solar cells to supercapacitors and sensors.
Mitochondria are the descendants of bacteria that settled down inside primordial eukaryotic cells, eventually becoming the power plants for their new hosts.
«These viruses are hijacking many of the host cell translation steps or pathways to favor the production of new virus progeny,» says Ruggieri.
New research out of Duke University shows that RNA viruses are littered with N6 - methyladenosine tags which affect the ability of these viruses to infect cells and, ultimately, their human hosts.
The phages infiltrate bacterial cells, where they commandeer the host machinery to make thousands of new phages; then they escape through the bacterial cell wall — killing the host — and spread to infect their next victims.
The new imaging technique will allow researchers to see the effects of novel drugs on this final stage in the parasite's invasion strategy, researchers report online on this week in Cell Host & Microbe.
«Bacterial and host cell proteins interact to regulate Chlamydia's «exit strategy»: New research suggests major role for calcium ion signaling in release of Chlamydia from infected cells
Writing online Nov. 23 in the journal Molecular Cell, a team of researchers from the University of Wisconsin — Madison describes new research helping tease out the mechanics of how the gut microbiome communicates with the cells of its host to switch genes on and off.
Instead of using light energy to produce food to support the salamander host, as happens in coral - algae interactions, the algae in salamander cells struggle to adapt to their new environment.
In the new papers, according to STAT, scientists will report that the organoids survived for extended periods of time — two months in one case — and even connected to lab animals» circulatory and nervous systems, transferring blood and nerve signals between the host animal and the implanted human cells.
New research from La Jolla Institute for Allergy and Immunology lays the groundwork to parse how the virus interacts with its host and causes disease by pinpointing CD8 + T cells, a subset of T cells more commonly known as cytotoxic or killer T cells, as important gatekeepers that control Zika infection or limit the severity of disease.
The information role of DNA was further supported in 1952 when Alfred Hershey and Martha Chase demonstrated that to make new viruses, a bacteriophage virus injected DNA, not protein, into the host cell (see How Viruses Work for more information).
It's the death and inevitable breakdown of these cells that make your body look cozy to a whole host of new bacteria.
ES cells provide new opportunities for developing and establishing new treatments, including transplantation tolerance induction, because of their unique characteristics: lack of MHC antigens, poor expression of co-stimulatory molecules and lack of T cells that can trigger graft - versus - host reaction.
My laboratory seeks to better understand the pathological interplay of human retroviruses like human immunodeficiency virus (HIV) and human T - cell lymphotropic virus (HTLV) with their cellular hosts with the goal of providing new approaches for prophylaxis and therapy.
Two new NSG mouse models allow immunological dissection of graft - versus - host disease (GVHD) responses and in vivo testing of therapeutic agents targeting human CD4 T cells.
The Materials Project, a Google - like database of material properties aimed at accelerating innovation, has released an enormous trove of data to the public, giving scientists working on fuel cells, photovoltaics, thermoelectrics, and a host of other advanced materials a powerful tool to explore new research avenues.
Through a new study that explores one aspect of how the virus hijacks host cell machinery to replicate itself, UNC Lineberger Comprehensive Cancer Center researchers have gained insight into the workings of a potential drug target for hepatitis C.
A. Bacteria: completely independent, able to eat and reproduce quickly (can develop into millions of cells in 4 hours) B. Virus: 1/1000 smaller than a bacterial cell, not alive, attaches to a host cell and injects its material into that cell and uses the genetic material to make new viruses - the host cell bursts and releases the viruses C. Parasites:
Once introduced into the bloodstream of the new host, the virus is replicated in the muscle cells (not in the bloodstream), passing via the peripheral nervous system toward the central nervous system.
Soon the host cell becomes a virus factory, replicating thousands of new viral organisms to go forward and infect new cells.
It's been said over and over again — in the news, in the New England Journal of Medicine, in a letter from over 40 of the nation's leading medical institutions — that fetal tissue samples are unlike any other cell research, helping scientists find cures for a host of diseases.
With more CD4 + cells at the scene of the infection, there are more cells for HIV to target, increasing its chance of successfully infecting a new host.
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