Sentences with phrase «cells of the central nervous system»

When blank slate stem cells are exposed to a soft as opposed to a hard surface on which to grow, they begin to transform themselves into neurons, the large, complex cells of the central nervous system.

The nerve cells of the central nervous system (CNS), which is composed of the spinal cord, the brain, and the retina, must be supplied with sufficient oxygen and nutrients through the blood vessel system during development and their subsequent function.

The scientists have used supporting cells of the central nervous system, glial cells, to regenerate healthy and functional neurons, shown in green in this image in the brain of a mouse with Alzheimer's disease.

The scientists have used supporting cells of the central nervous system, glial cells, to regenerate healthy, functional neurons, which are critical for transmitting signals in the brain.

Parkinson's disease (PD) and such neurodegenerative diseases as Huntington's and Alzheimer's are characterized by protein misfolding, resulting in toxic accumulations of proteins in the cells of the central nervous system.

We are not espousing completely eliminating fat from their diet since these molecules are also important in maintaining the integrity of cells especially the cells of the central nervous system.

The immune system, specifically microglia, the primary immune cells of the central nervous system (CNS), has been implicated in ALS disease progression.

Not exact matches

One day, Reynolds says, a version of InVivo's implant, packed with stem cells or hormones, might help the six million Americans who are chronically paralyzed from SCI and other central nervous system disorders improve their level of functioning.

And, perhaps most strikingly, a team at a gaggle of New York research institutions published a paper showing how they'd used hPSCs to cook up — in just days, rather than several months — cortical neurons (critical central nervous system cells) that had normal electrophysiological signaling properties.

In general it seems that we can be sure there are souls only where there are central nervous systems providing sufficient stimulus in some locus in an animal body for a unified experience to emerge far more complex than that of individual molecules or cells.

A single human egg cell is alive, but it has no experiences like those of an adult, or a child, or even of an animal with a central nervous system.

Higher animals all seem to contain at least one such society, called a «living person,» present in the body in addition to the cells and molecules of the central nervous system, even though dependent upon them.

As Birch notes, what is required physiologically for consciousness to emerge is a specialization of cells leading to a central nervous system with sense organs oriented to messages from the external world.

Specifically, when capsaicin frequently binds to receptors within the human central nervous system's TRPV1 channel (the sensory receptor system for pain and heat detection), these receptors deplete and this depletion results in a whole host of benefits for the central nervous system at large, including terminating cancer cells, increasing the metabolic rate and digestive efficiency, increasing circulatory blood flow, and combatting inflammation, and making you feel better about the world.

In fact, it is the most abundant mineral in our bodies, with over 99 per cent stored in our bones and teeth and the rest stored in other parts of the body, including muscles, blood and the fluid in between cells, where it acts as a «messenger» for the central nervous system.

«Once it's depolarized, a neuron releases a neurotransmitter, which starts the communication from one cell to another, moving from the periphery of the body to the central nervous system.»

It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.

We believe that they will also lead to the development of a whole new range of therapies for neurodegenerative diseases of the central nervous system,» explains corresponding author of the study Jihwan Song, professor and director of Neural Regeneration and Therapy Group at the CHA Stem Cell Institute of CHA University.

«Opioids have both analgesic and rewarding effects and they have these effects through mu opioid receptors and these receptors are expressed in pain terminals in the spinal cord and in areas of the brain that regulate pain but are also expressed in areas that regulate reward and a sense of pleasure,» Boyle said, referring to cells found in a person's central nervous system that bind to naturally occurring opioid compounds and reduce pain and make people feel much better.

Normally, the cells Nobel used for the test would divide and give rise to a specialized type of cell in the central nervous system called an oligodendrocyte.

These cells developed normally, and within two weeks had formed neural rosettes, clusters of cells that form the central nervous system.

13 In vertebrate embryos, neural crest cells (NCCs) form along the dorsal side, or crest, of the neural tube (the proto - central nervous system).

Beyond lung cancer, TiY is able to target TICs in 28 types of human cell lines derived from the central nervous system, melanoma, breast, renal, ovarian, colon, and prostate cancer.

Using the JEDI technology, Mount Sinai researchers uncovered evidence that immune cells can find cells in the brain expressing their target antigen, even in non-infected states, which provides evidence of an immune surveillance pathway within the body's central nervous system.

Treatment with an investigational CAR T - cell therapy induced complete remission of a brain metastasis of the difficult - to - treat tumor diffuse large - B - cell lymphoma (DLBCL), which had become resistant to chemotherapy — the first report of a response to CAR T - cells in a central nervous system lymphoma.

In the adult central nervous system, the vasculature of the neurogenic niche regulates neural stem cell behavior by providing circulating and secreted factors.

An important part of the study tested the ability of the radiolabeled antibody to reach HIV - infected cells in the brain and central nervous system.

The ELH genes are expressed, not only in the bag cells, but in an extensive system of neurons distributed in four of the five ganglia of the central nervous system.

The cells originate outside the central nervous system in the ectoderm of the body wall and appear to migrate to their final locations within the central nervous system by crawling along strands of connective tissue.

Using a powerful imaging technique that allowed the scientists to track the presence and movement of parasites in living tissues, the researchers found that Toxoplasma infects the brain's endothelial cells, which line blood vessels, reproduces inside of them, and then moves on to invade the central nervous system.

In the case of type 1 diabetes, it destroys the insulin - producing cells in the pancreas, and in multiple sclerosis it strikes the central nervous system.

«Glial cells are the most abundant in the central nervous system and critical to the function of the neuronal network,» Kozai says.

To explain their findings, the authors suggest that resveratrol's vasodilating effects via endothelial cells might enhance infiltration of inflammatory cells into the central nervous system, which in turn might play a key role in the pathogenesis of MS.

In vertebrates, the axons of many neurons are sheathed in myelin, which is formed by either of two types of glial cells: Schwann cells ensheathing peripheral neurons and oligodendrocytes insulating those of the central nervous system.

The device, part of the Lab's iCHIP (in - vitro Chip - Based Human Investigational Platform) project, simulates the central nervous system by recording neural activity from multiple brain cell types deposited and grown onto microelectrode arrays.

Specifically, stem cell scientists at McMaster can now directly convert adult human blood cells to both central nervous system (brain and spinal cord) neurons as well as neurons in the peripheral nervous system (rest of the body) that are responsible for pain, temperature and itch perception.

We can also make central nervous system cells, as the blood to neural conversion technology we developed creates neural stem cells during the process of conversion.»

«Now we can take easy to obtain blood samples, and make the main cell types of neurological systems — the central nervous system and the peripheral nervous system — in a dish that is specialized for each patient,» said Bhatia.

The findings, published in Cell Host & Microbe, may represent a breakthrough strategy for treating West Nile Virus after virus invasion of the brain and the central nervous system, noted senior author Priti Kumar, M.D., associate professor of infectious disease at Yale School of Medicine.

These problems are caused by a type of white blood cells called T cells that, after becoming activated, find their way into the brain and attack the protective covering — myelin — of neurons in the brain and spinal cord, causing inflammation and damage to the central nervous system.

The genes in question are all involved in the production of myelin, which forms the fatty insulation around nerve cell axons that enables efficient communication in the central nervous system.

The same cells, mysteriously, have been found on occasion in the central nervous system of healthy people.

A newly identified genetic disorder associated with degeneration of the central and peripheral nervous systems in humans, along with the genetic cause, is reported in the April 24, 2014 issue of Cell.

It normally takes a long time for the rabies virus to traverse the central nervous system, whereas Youn's nanoparticles made it to tumor cells in a matter of hours.

He said he used techniques to differentiate pluripotent stem cells into cells that are designed to become neural tissue, components of the central nervous system or other brain regions.

Dose - densified chemoimmunotherapy followed by systemic central nervous system prophylaxis for younger high - risk diffuse large B - cell / follicular grade 3 lymphoma patients: results of a phase II Nordic Lymphoma Group study.

Summary: The central nervous system (CNS) is made up of neuronal cells and support cells, called glia.

Through the use of immunological, molecular and cell biological techniques, my laboratory is defining the phenotype and function of different monocyte subsets that infiltrate the central nervous system following traumatic injury.

Multiple sclerosis (MS) is among the most common neurological diseases in young adults, affecting 350 000 individuals in the United States and 2 million worldwide.1 Prevailing thought is that MS is an autoimmune disorder whereby an unknown agent or agents triggers a T cell — mediated inflammatory attack, causing demyelination of central nervous system tissue.2

The retina is a relatively easily accessible part of the central nervous system, which makes it an attractive target for correction with iPS cells.