It is an autoimmune disease caused by
cells of the immune system mistakenly attacking and destroying the insulin - producing cells of the pancreas.
Not exact matches
Usually, the body's own
immune system — which normally fights harmful bacteria and viruses —
mistakenly destroys the insulin - producing (islet, or islets
of Langerhans)
cells in the pancreas.
«Our study reveals a new mechanism that could be harnessed for biological therapies for lupus and other autoimmune diseases, where the
immune system mistakenly targets the body's own
cells,» says senior study author Boris Reizis, PhD, professor
of Pathology and Medicine at NYU Langone.
The four children also had more
of the types
of species that are known to trigger gut inflammation, a possible prelude to type - 1 diabetes, in which the body's
immune system mistakenly produces antibodies that attack and destroy the beta
cells of the pancreas that normally make insulin.
Loss
of insulin - producing beta
cells has long been recognized as a cause
of Type 1 diabetes, in which the
immune system mistakenly attacks and destroys beta
cells.
«This debris left by dead
cells can
mistakenly signal to the body that there is an infection that warrants
immune action, triggering the innate
immune system,» said Bruce A. Sullenger, Ph.D., director
of the Duke Translational Research Institute.
The treatment is designed to stop the
immune systems of those with type 1 diabetes, a condition which usually develops in childhood, from
mistakenly destroying the
cells which create insulin.
Having discovered a genetic «key» (called P - TEFb) that is important in both cancer
cell growth and
immune cell differentiation, they tested the drugs on a mouse model for uveitis, an incurable eye condition in which the
immune system mistakenly attacks healthy tissue leading to inflammation
of the uvea (the middle layer
of the eye).
It is generally understood that autoimmune disease is a scenario in which the
immune system mistakenly attacks part
of the body, thinking that healthy
cells are foreign or harmful antigens.
[Phosphate] destroys the lipid layer
of the skin; [fragrances and dyes] activate the T
cell arm
of the
immune system, which can
mistakenly attack normal
cells.»
The
immune system of someone with Hashimoto's thyroiditis
mistakenly recognizes normal thyroid
cells as foreign tissue, and it produces antibodies that may destroy these
cells.
However, when a person has an autoimmune disease, the
immune system mistakenly turns on itself, targeting
cells, tissues and organs
of your own body.