The mice were found to have an abnormal microbiome, along with damaged junctions between
the cells of the intestinal lining.
Different complex carbohydrates (serving the function of pre-biotics) feed different strains of intestinal flora and promote good intestinal health, providing short chain fatty acids for
the cells of intestinal lining as a source of energy and also create a pH favoring good intestinal health — this all reducing the risk of cancer, also by controlling the proliferation and promoting apoptosis of the intestinal lining tissue.
In the case of Crohn's disease, the inflammation in the intestines is believed to cause the widening of the junctions (TJs or tight junctions) between
the cells of the intestinal lining.
I've been reading so many resources on how gluten can cause gaps in
the cells of your intestinal lining.