Not exact matches
In a rare appearance Dr. Chandan Sen, Director, OSU Center for Regenerative Medicine &
Cell - Based Therapies will explain how this breakthrough came about and how the technology is leading to other medical discoveries and how the principle can be used to generate any
tissue out of skin or fat which is abundant in human body.
Millet is one
of the least allergic grains
out there and it's mineral and vitamin content helps boost energy and build healthy
cells and
tissue.
Intermittent fasting allows the body to shed off inferior
cells and dump toxins
out of the fat
cells and deep within organ
tissues.
Because
of this, their babies had lower hemoglobin (carries oxygen to
tissues and carbon dioxide
out) and hematocrit (percentage
of red blood
cells inside the blood) levels compared to the babies
of non-drinkers.
Most other lubricants, freshening gels, and massage oils on the market are hypo or hypertonic (too low or too high
of a salt concentration compared with vaginal
tissues), and cause water to be pushed into, or pulled
out of the vaginal
cells.
«If we want to treat the greatest number
of diseases, we need to figure
out how to get these molecules inside the
cells of patients — not just increasing the number
of target
cells but also hitting
tissues other than the liver,» says Anderson, who co-founded a company called CRISPR Therapeutics to pursue those goals.
By plucking
out delicate, live
tissue during neurosurgery and then studying the resident
cells, researchers have revealed a partial cast
of neural characters that give rise to our thoughts, dreams and memories.
They would add a liter
of the
tissue to two liters
of seawater and shake the mixture 75 times — no more, no less — to make «the individual light - producing
cells pop
out of the
tissue,» according to Bill Ward, a bioluminescence researcher at Rutgers University in New Jersey who was a post - doc in Cormier's laboratory.
For example, to tease
out what various sound signals might mean, the researchers had to figure
out how kelp
tissues respond to sound (turns
out that it's highly dependent on alginate content, a gummy
cell wall component
of kelp).
Small populations
of adult stem
cells with somewhat limited developmental potential are responsible for the body's ability to heal injuries and replace worn
out cells and
tissues, and evidence is growing that rare cancer stem
cells are responsible for the uncontrolled growth
of some malignant tumors, including glioblastoma.
Compared with unheated mice, the animals with the faux fever had twice as many white blood
cells migrating
out of the blood vessels and into the lymph
tissue that lines the skin and gut, which is where they need to be to attack incoming pathogens.
For example, an MDM2 - targeting drug shrank deep -
tissue fat
cell tumors in just one
out of 20 patients in a phase I safety trial, published in 2012.
Thinking that A20 was only produced in a few
tissues, researchers at the University
of Chicago originally set
out to pinpoint A20's function in certain white blood
cells in the intestine.
In this research, Yousaf and his team made a scaffold free beating
tissue out of three
cell types found in the heart — contractile cardiac muscle
cells, connective
tissue cells and vascular
cells.
Now, many research advocates are wondering how Price's mix
of views might play
out in the new administration's approach to a wide range
of issues, including funding, research involving human embryonic stem
cells and fetal
tissue, and the appointment
of a new NIH director.
If a sea turtle takes a bite
out of a jellyfish, the injured animal can quickly grow new
cells to replace the lost
tissue.
Compared to people with periodontitis or gingivitis who were otherwise healthy, one molecule in particular stood
out: people with LAD had very high levels
of IL - 17 mRNA and IL -17-expressing
cells in their gum
tissue.
It turns
out that the hormonelike chemicals in plastic may remodel our
cells and
tissue during key stages
of development, both in the womb and in early childhood.
We think this pathway might act to get rid
of infected
cells, clearing them
out so the infection can not spread to healthy
tissue.
Tumours spread with the help
of enzymes called matrix metalloproteinases (MMPs), which destroy the connective
tissue between
cells and organs, allowing tumour
cells to break
out of the original site and enter new ones.
Part
of the trouble is the ingredients: Subtle variations in
tissue - culture chemicals and Matrigel, or in different stem
cell lines and how they are grown first in 2 - D culture, can have a big impact on how the organoids turn
out, Novitch says.
Right now they can create very thin layers
of muscle
tissue that are a few layers thick or something, but beyond that, you need a three - dimensional kind
of a structure that provides nutrients in and
out and removes waste, keeps the
cells alive essentially.
Hilde Mangold (1898 - 1924) Under the guidance
of Hans Spemann, she carried
out the experiments that led to the discovery
of the organizer effect, which directs the development
of embryonic
cells into
tissues and organs.
Achieving this goal has been hampered by the technical difficulty
of isolating pure cancer
cells out of the tumor
tissue that contains both tumor
cells as well as normal
cells.
«The research carried
out in zebrafish unit
of the University
of Helsinki showed that in addition to
cell cultures, these optogenetic tools worked also in living
tissues,» says Academy Research Fellow Jari Rossi.
Since the 1970s
tissue engineers have been figuring
out how to grow skin, bone, cartilage, and even parts
of vital organs using
cells harvested directly from patients.
He says, «Cytopathologists spend most
of the workday in the lab looking at
cell and
tissue slides, so I really relished the opportunity to get
out and speak with patients.»
But if homologous recombination could be worked
out in human (embryonic) stem
cells, then cardiomyocytes with mutations in ion channels could be derived, as well as a large number
of other very useful disease models
of other
tissues.
Like
cells in all cancers, the B
cells begin to grow
out of control, creating tumors in the lymph nodes, spleen or other
tissues.
The hepatocytes are first patterned onto surfaces dotted with tiny spots
of collagen, and then surrounded by supportive
tissue made up
of stromal
cells, which act as connective
tissue and support the hepatocytes in carrying
out their liver functions.
In contrast to necrosis, which is a form
of cell death that results from acute
tissue injury and provokes an inflammatory response, PCD is carried
out in a regulated process that generally confers advantages during an organism's life cycle.
When the research team selectively deleted the reserve stem
cells in calorie - restricted mice, their intestinal
tissue's regeneration capabilities were cut in half, implicating these
cells as having an important role in carrying
out the benefits
of calorie restriction.
The finding made intuitive sense; researchers studying other
tissue types had shown that activating mTOR can drive dormant
cells out of quiescence, a necessary step for regeneration.
Studies in animals suggest that mesenchymal stem
cells play important roles in the body's ability to heal after an injury, although researchers are still working
out the signals and steps required to steer their differentiation into one type
of tissue or another.
The researchers solved this problem by developing markers to label the
cells of interest and then testing different enzymes and other reagents to draw them
out of tissues.
«We had to figure
out how to dissociate the
tissue into single
cells without completely obliterating everything,» said Anastasia Gromova, the study's first author, now a graduate student at the University
of California, San Diego, who spearheaded the project while interning at TSRI during her undergraduate years.
In most
of our
tissues, adult stem
cells hang
out in a quiet state — ready to be activated in case
of infection or injury.
Working with mouse, fly and human
cells and
tissue, Johns Hopkins researchers report new evidence that disruptions in the movement
of cellular materials in and
out of a
cell's control center — the nucleus — appear to be a direct cause
of brain
cell death in Huntington's disease, an inherited adult neurodegenerative disorder.
«The mammary gland has a huge amount
of stuff that it has to get rid
of quickly after lactation, but if you just have immune
cells taking the dead
cells out, you still get chronic inflammation and
tissue damage,» says Charles Streuli, who supervised the study.
Adult organisms ranging from fruit flies to humans harbor adult stem
cells, some
of which renew themselves through
cell division while others differentiate into the specialized
cells needed to replace worn -
out or damaged organs and
tissues.
So, at the dawn
of our universe — and I have to emphasize our universe, because there could be others — so, dawn
of our universe, physicists think there was one type
of force, one type
of matter and that as the cosmos expanded, as space expanded, it cooled and things started to condense
out like snow flakes, and over time that single force broke, it differentiated; and something similar happens in the human body as we develop from a single
cell; we differentiate, different
tissues form in our bodies, different layers
of tissues.
These components then slip
out of the fat
cells and into the bloodstream, where they are accessible to
tissues throughout the body.
It turns
out there are some key molecular interactions that are stimulated by movement and which guide the
cells and
tissues of the embryo to build a functionally robust yet malleable skeleton.
By using fruit fly as a model system, Minna Poukkula working at the Institute
of Biotechnology, University
of Helsinki, has found
out how actin - rich protrusions contribute to
cell migration in animal
tissues.
And because tumors typically have a leaky, ill - formed vasculature, the particles tend to leak
out at the site
of cancer
tissue and be picked up and internalized inside tumor
cells.
But many in the field will be waiting for the next steps: testing whether the resulting mouse pups are genetically normal, trying
out the technique in other animals, and using other and less controversial types
of cells — such as stem
cells that can be extracted and cryopreserved from adult testicular
tissue — as the starting point.
Viral agents then burst
out of the stem
cells, infecting the cancer
tissue — but leaving healthy brain
tissue alone.
Northwestern researchers are analyzing
tissue at the nano — as opposed to the micro — scale to root
out cells whose nuclei have greatly expanded or otherwise show irregularities that could be signs
of impending malignancy.
To find
out,
cell biologist Paola Vermeer
of the University
of Iowa in Iowa City and colleagues first examined donated human lung
tissue.
But airway epithelial
cells contain both molecules at all times, so researchers wondered what keeps healthy
tissues from growing
out of control.