Sentences with phrase «cells produces less»

«Our work predicts that reducing the number of circulating cancer cells produces less metastasis,» Pellecchia said.

In mice with Crohn's - type inflammation, the Paneth cells produce less lysozyme, an important anti-microbial enzyme.

They found that malignant cells produced less than 20 per cent the amount of BRCA1 mRNA made by healthy breast cells.

However, Crebbp + / - stroma cells produce less of these factors.

Not exact matches

Cargill, one of the largest global agricultural companies, has joined Bill Gates and other business giants to invest in a nascent technology to make meat from self - producing animal cells amid rising consumer demand for protein that's less reliant on feed, land and water.

When less milk is released from the milk making cells, the body then produces less because it think it needs less, and your supply could drop.

STOP SIGNS Brainlike structures grown from autistic patients» stem cells (right) produced greater numbers of brain cells that make other brain cells less active (green and red) compared with structures grown from the cells of a non-autistic family member (left).

They would add a liter of the tissue to two liters of seawater and shake the mixture 75 times — no more, no less — to make «the individual light - producing cells pop out of the tissue,» according to Bill Ward, a bioluminescence researcher at Rutgers University in New Jersey who was a post - doc in Cormier's laboratory.

Autism risk mutations inactivate this gene and, in the absence of their own ability to produce carnitine and without adequate outside supplementation, neural stem cells become less efficient at self - renewal.

The less E-cadherin and Epcam are produced, the looser the bonds to other cells become.

In mice, the Runx2 knock - in myeloma cells produced greater tumor growth and a wider spread of disease compared with the original myeloma cells; conversely, the Runx2 knock - down cells had less tumor growth and disease spread.

While adiponectin is produced by fat cells, Medina said, obese people have less of it.

The researchers also tested a Runx2 knock - down variant of a human multiple myeloma cell line and found that it produced significantly less tumor growth in immunodeficient mice than the original human multiple myeloma cells.

Obesity is a key driver of Type 2 Diabetes, given that excess abdominal fat causes fat cells to release a «pro-inflammatory» chemical which can make the body less sensitive to the insulin it produces and disrupt the ability of insulin - responsive cells to fulfill their function.

«They continue to have the gene and they produce VEGF - A, but it's like the patient's cells don't realize they could be more protected or suffer from the disease much less if the cells produce more of this particular protective factor.»

He suspects that the mitochondria in people predisposed to developing type 2 diabetes produce less energy, causing cells to demand less fuel, which triggers insulin resistance.

Adult stem cells: They have less flexibility and «stemness» to change into different cell types, but they can still produce new cells, specialized to become part of a particular organ or tissue, such as muscle cells or neural cells.

«But we discovered that attaching microbeads to the cell's surface amplifies the cell's response during cavitation and produces the same result with much less risk of cellular injury.»

«Ferric citrate binds the phosphorus in food and also increases iron in the blood, and it allows patients to need less or no IV iron and medicines to make their bone marrow produce more blood cells,» said Dr. Lewis.

When transplanted into human cells in the laboratory, the mammoth TRPV3 gene produced a protein that is less responsive to heat than an ancestral elephant version of the gene.

The mutant mice produced less insulin — the hormone made in the pancreas that helps cells burn sugar — and they were plump and diabetic, with high levels of glucose in their blood.

This is thought to be due to the beta cells dying off or at least gradually producing less insulin, amongst other things.

While most B cells have a low affinity for pathogens, which might effectively fend off a relatively mild virus, Tfh (with the stimulation of ICOS) allows the select few that produce highly specific and more strongly reactive antibodies to proliferate and outcompete their less specific brethren.

While it has been well - established that people should avoid behaviors like smoking to decrease cancer risk, it is less well - known that each time a normal cell divides and copies its DNA to produce two new cells, it makes multiple mistakes.

Photoswitches inserted into retinal ganglion cells (RGC) of blind mice produce much less variety of response (all evenly red means the cells fire at the same time), while blind mice with photoswitches inserted into bipolar cells (ON - BC driven) exhibit much more variety in their retinal response to light, closer to that of normal mice.

These properties make the cells ideal for things like windows or roofs, although they are probably less suitable for large - scale commercial applications, such as solar farms, because they need more area to produce the same amount of electricity as more typical silicon - based solar cells.

Compared to skinnies, muscular men also tended to produce fewer infection - fighting white blood cells and less of an important immune molecule called C - reactive protein, which helps destroy pathogens.

One goal of the research led by Savin is to find ways to produce equally efficient solar cells using the less expensive but impure silicon rather than the more expensive purified silica.

Because there is no combustion, fuel cells run extremely cleanly: Their emissions are just water and carbon dioxide, and they produce less than half as much CO2 per kilowatt - hour as do traditional power plants.

As a result, the cell «contracts, but it produces less than normal force,» Sweeney says.

In cancer cells there is a switch to using glycolysis, a process that requires less oxygen and produces lactate as a by - product.

These new results are expected to accelerate the development of the next generation of flexible carbon - based solar cells, which are both more efficient and less expensive to produce.

Although mitochondria, the tiny capsules that produce energy for the cell, are known to play some role in neurodevelopmental and psychiatric disorders, the contribution of mitochondrial dynamics (mitochondrial trafficking, the regulated fusion and fission, and destruction of mitochondria) has been less clear.

In another experiment, mice lacking the cells that produce serotonin scratched less than normal mice when exposed to a skin irritant.

Lysy says that because the insulin - producing cells originate from pancreatic tissue there is less risk that they will turn cancerous after the transplant.

The findings suggested that different types of blood cells produce vastly different amounts of protein per hour, and stem cells in particular synthesize much less protein than any other blood - forming cells.

They found that there was less surfactant production and fewer cells producing it in the offspring from mothers in the over-nutrition model.

These changes may include producing less IgE, producing «blocking» IgG antibodies, and producing more regulatory T cells, promoting tolerance and a less active immune response.

In response to signals from inside and outside cells, transcription factors attach to the DNA and cause specific genes to be more or less activated, producing more or less of the corresponding protein.

Older or non-validated cell lines may produce gesicles less efficiently, thereby decreasing the gesicle concentration and subsequent editing efficiency.

As cancerous cells become more invasive they produce less E-cadherin.

A disease which manifests when the dopamine - producing nerve cells in the brain are damaged and thus produce less and less of this important chemical.

But preliminary results suggest that iPS cells produced without viruses or genetic manipulation show less premature senescence.

Specifically, 8.0 ± 5.8 % of the SC area of cell - injected eyes produced thresholds less than 0.8 log units, 22.0 ± 8.5 % produced thresholds less than 1.5 log units and 67.7 ± 10.0 % yielded thresholds less than 2.1 log units, with best test points falling within the normal, non-dystrophic range.

But the mutation that Walsh's team identified causes cells to produce a TRAPPC9 protein that is less than half its usual length.

The researchers found that, when stimulated by insulin, diabetic fibroblasts produced less of the VEGF (vascular endothelial growth factor) signaling protein, a key player in boosting the growth of blood vessel cells, than normal fibroblasts did.

While the plating efficiency of the V+S + fraction was reduced and produced 4-fold less colonies than the V − S + fraction, both fractions gave rise to identical colonies that contain equivalent populations of V + and V − cells (Figure 7A, Table 1).

Renowned for our work in beta cell production and research, we are conducting studies to expand and boost insulin - producing cells and make them less susceptible to attack by the immune system.

Parkinson's Disease (PD) manifests when the dopamine - producing nerve cells in the brain are damaged and thus produce less and less of this important chemical.

Takeda et al. engineered mice that were either unable to produce a particular LPA receptor on their T - cells, or that produced less LPA than normal.