Not exact matches
In March, the U.S. Food and Drug Administration (FDA) approved BLINCYTO for the treatment of adults and children with B - cell precursor acute lymphoblastic leukemia in first or second complete remission with minimal residual disease (MRD) greater than or equal to 0.1 percen
In March, the U.S. Food and Drug Administration (FDA) approved BLINCYTO for the treatment of
adults and children with B -
cell precursor acute lymphoblastic leukemia
in first or second complete remission with minimal residual disease (MRD) greater than or equal to 0.1 percen
in first or second complete remission with minimal residual disease (MRD) greater
than or equal to 0.1 percent.
However, since there are simply not enough stem
cells in cord blood alone to treat an
adult sized patient, Americord offers a proprietary process for storing the entire placenta and preserving up to 10 times more stem
cells than cord blood banking alone.
«What we see with the reporter
in adult tissues is very surprising and much more complex
than we had thought,» says Stelzer, who is a co-author of the
Cell Reports paper.
For the first time, stem
cells from
adults rather
than embryos have relieved Parkinson's symptoms
in monkeys.
In the latest research, described online this week in the journal Cell Reports, Stelzer used the reporter system in mice to discover that imprinted methylation in developing and adult tissues is actively regulated rather than merely maintained in stable fashio
In the latest research, described online this week
in the journal Cell Reports, Stelzer used the reporter system in mice to discover that imprinted methylation in developing and adult tissues is actively regulated rather than merely maintained in stable fashio
in the journal
Cell Reports, Stelzer used the reporter system
in mice to discover that imprinted methylation in developing and adult tissues is actively regulated rather than merely maintained in stable fashio
in mice to discover that imprinted methylation
in developing and adult tissues is actively regulated rather than merely maintained in stable fashio
in developing and
adult tissues is actively regulated rather
than merely maintained
in stable fashio
in stable fashion.
So far Kajander and his colleagues have found the nanobacteria
in cattle blood,
in 80 % of samples of commercial cow serum
in which mammalian
cells are grown
in the lab, and
in the blood of nearly 6 % of more
than 1000 Finnish
adults tested.
Stem
cells harvested from embryos rather
than adults remain the most powerful for cloning and other purposes; Yang's team showed that cloning from such
cells succeeded
in 49 percent of attempts and led to 18 mouse pups.
Indeed, the diversity of T
cell receptors generated before birth is known to be lower
than in adults, increasing the odds of two unrelated people sharing the same receptor.
«Does starvation exert a stronger effect on telomere length
in the reproductive
cells of
adults than in the leukocytes of children?
Genes involved
in the maturation of these
cells were expressed at the wrong time, and the
cells proceeded to an
adult stage earlier
than usual.
A new study
in rats shows that lacing a penis graft with
adult stem
cells yields better healing and sexual function
than using the graft alone.
Adult male mice also started off with fewer of the lymphoid cells in the lungs than adult females, the researchers found: Female mice had about 1 1/2 times as many of these immune cells as m
Adult male mice also started off with fewer of the lymphoid
cells in the lungs
than adult females, the researchers found: Female mice had about 1 1/2 times as many of these immune cells as m
adult females, the researchers found: Female mice had about 1 1/2 times as many of these immune
cells as males.
One of the expected dangers of cloning is that worn down telomeres will be inherited from the
adult cells used
in lieu of an egg or sperm
cell, and indeed the telomeres of
adult clones are often shorter
than normal.
When the researchers used fetal breast tissue rather
than adult tissue from mice, they were able to pinpoint which
cells were stem
cells but the
cells would rapidly change when grown
in a dish.
In other words, they can develop into each of the more
than 200
cell types of the
adult body as long as they are specified to do so.
Adult rats living
in disrupted environments produce fewer new brain
cells than rats
in stable societies, supporting theories that unstable conditions impair mental health and cognition
Experienced
adults were more
than twice as likely to crash or have a near miss when dialing a
cell phone as when they did not dial and drive, but did not have an increased risk while engaging
in other tasks secondary to driving.
In contrast to embryos, lipid - containing structures in enterocytes and in epidermal cells of adult animals are smaller in mutants than in wild type animal
In contrast to embryos, lipid - containing structures
in enterocytes and in epidermal cells of adult animals are smaller in mutants than in wild type animal
in enterocytes and
in epidermal cells of adult animals are smaller in mutants than in wild type animal
in epidermal
cells of
adult animals are smaller
in mutants than in wild type animal
in mutants
than in wild type animal
in wild type animals.
In contrast to embryos, lipid - containing structures in intestinal and epidermal cells of adult W01A8.1 null mutants (Figs. 5J and 5L) were smaller than lipid - containing structures in control animals (Figs. 5I and 5K
In contrast to embryos, lipid - containing structures
in intestinal and epidermal cells of adult W01A8.1 null mutants (Figs. 5J and 5L) were smaller than lipid - containing structures in control animals (Figs. 5I and 5K
in intestinal and epidermal
cells of
adult W01A8.1 null mutants (Figs. 5J and 5L) were smaller
than lipid - containing structures
in control animals (Figs. 5I and 5K
in control animals (Figs. 5I and 5K).
In spite of mismatching, cord blood
cells cause less graft versus host disease (GVHD)
than adult cells.
Are cord blood transplants more tractable for children
than for
adults in terms of the amount of cord blood that's needed for a transplant relative to other stem
cell sources?
This suggests that embryonic
cells may be more useful
than adult - derived
cells in some cases, and that the strategy described here may promote any intrinsic self - organizing capacity held by embryonic
cells.
Embryonic stem
cells — the subject of so much controversy (witness the new ruling blocking their use)-- were first cultured
in the lab a little more
than a decade ago;
in 2006, there was another breakthrough when
adult cells were coaxed into becoming induced pluripotent stem
cells.
Included among the numerous recipients of Mr. Sanford's gifts, that total more
than one billion dollars, are: the Edith Sanford Foundation for Breast Cancer that was created
in 2012 by a gift of $ 100 million
in honor of Mr. Sanford's mother who died of breast cancer when he was four years old; the Sioux Valley Hospitals and Health System, which renamed itself Sanford Health
in 2007,
in recognition of a $ 400 million gift; a $ 125 million gift
in 2014 to establish Sanford Imagenetics, a program that will integrate genomic medicine into primary care for
adults; the University of California San Diego which received a $ 100 million gift for the creation of the Sanford Stem
Cell Clinical Center in 2013 to accelerate the translation of stem cell research discoveries by advancing clinical trials and patient therapies; the Burnham Institute for Medical Research that received a $ 50 million gift in 2010, and recognized its appreciation for both this and a 2008 gift of $ 20 million to the Sanford Center for Childhood Disease research at Burnham by then changing its name to Sanford Burnham Medical Research Institute; a $ 70 million gift to establish a particle physics laboratory named the Sanford Underground Research Facility; and the San Diego Consortium for Regenerative Medicine which received a gift of $ 30 million in 2008 and expressed its gratitude by renaming itself the Sanford Consortium for Regenerative Medic
Cell Clinical Center
in 2013 to accelerate the translation of stem
cell research discoveries by advancing clinical trials and patient therapies; the Burnham Institute for Medical Research that received a $ 50 million gift in 2010, and recognized its appreciation for both this and a 2008 gift of $ 20 million to the Sanford Center for Childhood Disease research at Burnham by then changing its name to Sanford Burnham Medical Research Institute; a $ 70 million gift to establish a particle physics laboratory named the Sanford Underground Research Facility; and the San Diego Consortium for Regenerative Medicine which received a gift of $ 30 million in 2008 and expressed its gratitude by renaming itself the Sanford Consortium for Regenerative Medic
cell research discoveries by advancing clinical trials and patient therapies; the Burnham Institute for Medical Research that received a $ 50 million gift
in 2010, and recognized its appreciation for both this and a 2008 gift of $ 20 million to the Sanford Center for Childhood Disease research at Burnham by then changing its name to Sanford Burnham Medical Research Institute; a $ 70 million gift to establish a particle physics laboratory named the Sanford Underground Research Facility; and the San Diego Consortium for Regenerative Medicine which received a gift of $ 30 million
in 2008 and expressed its gratitude by renaming itself the Sanford Consortium for Regenerative Medicine.
«If we can implant or stimulate these
adult stem
cells in damaged areas, it's possible we can do more
than fill
in lost nerve connections,» he says.
Blastoma: Tumors formed from embryonic tissue or developing
cells are known as blastomas and are more common
in children
than adults.
By observing the
cells in this system, they found that the embryonic cardiac fibroblasts promoted
cell division by the cardiomyocytes more efficiently
than adult cardiac fibroblasts.
There are many more differentiated
cells in the human body
than stem
cells, embryonic or
adult.
But
adult stem
cells are less flexible
than embryonic stem
cells and are harder to manipulate
in the lab.
Back
in 2011, for example, her lab demonstrated that beta
cells in newborn rats are immature
cells with very different gene expression and function
than adult beta
cells.
In general,
adult stem
cells have low plasticity, although reports of differentiation outside traditional lineage boundaries suggest that some
adult stem
cells may be more pluripotent rather
than multipotent.1
The Yale team found more
than 580 different genes that may play a role
in regeneration of axons
in nerve
cells, something that rarely occurs
in adult mammals but is of vital interest to scientists hoping to repair injuries to the central nervous system.
Sperm and eggs manufacture telomerase, but most
adult cells don't — and telomeres
in most
adult cells are shorter
than those
in sperm and eggs.
Giant
cell arteritis (formerly called temporal arteritis), the most common form of vasculitis
in adults, strikes after age 50 and affects more women
than men.
Dr. Fred Appelbaum, director of the clinical research division at the Fred Hutchinson Cancer Research Center
in Seattle, argued
in an accompanying editorial that
adult stem
cells harvested from bone marrow rather
than blood should be the norm.