Sentences with phrase «cells than in the human»

Not exact matches

Yesterday's ruling effectively said that Feng Zhang's adoption of the technique in human and mouse cells was, in fact, a new and patentable invention rather than an «obvious» extension of Doudna's and Charpentier's work.

As Bonhoeffer had understood in his prison cell, if brokenness and crisis were to become «that edge where change is possible,» this crisis would have to be sustained by something stronger than the human.

Example in point: Opposition to embryonic stem cell / human cloning research: It isn't anti science to oppose treating nascent human life like a corn crop or manufacturing embryos, anymore than it is anti science than the Animal Welfare Act the proscribes what can and can't be done in scientific research with some mammals.

It is the same when the artificial creation of a human cell is considered: «Nothing more than reproducing those conditions in which under the Law of Control and Direction, life emerges.»

Modern psychosomatic medicine has made some progress in analyzing along these lines; for example, it seems quite possible that the emotional tone of my soul may directly alter the patterns of physical feeling in my stomach.4 Still, we should not suppose too quickly that the aims of a human personality have any very effective direct influence on the molecules of body cells, other than those in the brain.

So at day 14, the number of nerve and brain cells in the human embryo is zero, and it has less complexity than the simplest microscopic worm and less feeling or intelligence than a parasite in dirty drinking water.

«Advancements in science and research have moved faster than the debates among politicians in Washington, D.C., and breakthroughs announced in recent years confirm the full potential of stem cell research can be realized without the destruction of living human embryos,» House Minority Leader John Boehner, R - Ohio, said Sunday.

Researchers hope the organoids will be better than lab animals or cells growing in culture at revealing how the human brain develops, both normally and when things go awry, and identify potential therapeutic or genome - editing targets.

In a human brain, the cells would need to travel a matter of millimeters or centimeters, up to 20 times farther than the 500 microns tested here, he says.

Hammer and colleagues Dennis Discher and Frank Bates attempted to scale up this process to make vesicles more than 10 micrometers in diameter — the size of human cells.

A new type of human stem cell, never seen in nature, should be better at making replacement organs than existing stem cells

«We've been hearing about their potential for more than a decade, but the results have always been in mice and rats, and no one has shown they're safe or effective in humans long term,» says Robert Lanza of Advanced Cell Technology in Marlborough, Massachusetts, the company that carried out the stem cell interventCell Technology in Marlborough, Massachusetts, the company that carried out the stem cell interventcell intervention.

Geron was bigger and better funded than ACT, and it was the first company to be approved by the US Food and Drug Administration (FDA) to test a therapy in humans based on embryonic stem (ES) cells.

This is likely, as recently discovered human globins appear to be involved in cell signaling rather than oxygen transport.

«The discovery of the microbiome and its significance represents a huge paradigm shift in our understanding of human health — there are more microbes living on us and in us than our own cells,» said Ingber, who is also the Judah Folkman Professor of Vascular Biology at Harvard Medical School and the Vascular Biology Program at Boston Children's Hospital, and Professor of Bioengineering at the Harvard John A. Paulson School of Engineering and Applied Science.

Strategies that boost the cell's quality control programs, rather than disarm specific pathologic proteins, have looked promising in lab animals that serve as models for human neurodegenerative disorders including Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.

In a human brain, 85 billion nerve cells communicate via trillions of connections using complex patterns of electrical jolts and more than 100 different chemicals.

Where permitted, ES cells should be drawn from sources in the following order: (1) existing ES cell lines, originating from ES cells derived from embryos less than 14 days old; and (2) surplus human embryos less than 14 days old that were created for fertility treatment.

In fact, there are more microorganisms living in and on the human body than there are human cellIn fact, there are more microorganisms living in and on the human body than there are human cellin and on the human body than there are human cells.

In a series of experiments, the researchers first identified a set of 19 transcription factors that were expressed at significantly greater levels in cultured human glioblastoma stem cells capable of tumor propagation than in differentiated tumor cellIn a series of experiments, the researchers first identified a set of 19 transcription factors that were expressed at significantly greater levels in cultured human glioblastoma stem cells capable of tumor propagation than in differentiated tumor cellin cultured human glioblastoma stem cells capable of tumor propagation than in differentiated tumor cellin differentiated tumor cells.

Mitochondria carry only a few genes, but they are so plentiful that it's often easier to find their DNA than the single full human genome in a cell's nucleus.

«They are more true - to - life than cells in dishes and more human - like than animal models,» said Hamilton.

The researchers also tested a Runx2 knock - down variant of a human multiple myeloma cell line and found that it produced significantly less tumor growth in immunodeficient mice than the original human multiple myeloma cells.

First, the destabilizing effects of VX - 770 on the corrected CFTR protein might be less robust in the human body than were the effects seen in lab tests using human lung cells.

Think sperm with multiple tails, no tails at all or in the case of one fruit fly, sperm that are nearly 6 cm long — roughly a thousand times longer than a human sperm cell.

In tests on human brain cells engineered to make more normal prions than usual, Hooper found that the cells secreted far less amyloid beta peptide than they would ordinarily.

With more than 800 members in the human genome, GPCRs are the largest family of proteins involved in decoding signals as they come into the cell and then adapt the cell's function in response.

Despite its many parts, the entire organism is a single cell of only about 10 microns in diameter, which is smaller than most cells in the human body.

In a boost for a controversial theory of aging, mice engineered to make a human protein that sponges up cell - damaging molecules live 19 % longer than other mice.

In the lab, the antibiotics had no harmful effect on normal cells, and since they are already approved for use in humans, trials of new treatments should be simpler than with new drugs — saving time and moneIn the lab, the antibiotics had no harmful effect on normal cells, and since they are already approved for use in humans, trials of new treatments should be simpler than with new drugs — saving time and monein humans, trials of new treatments should be simpler than with new drugs — saving time and money.

«In a single dose, APC - mimetic scaffolds led to two - to ten-fold greater expansion of primary mouse and human T cells than Dynabeads.

In a screen of more than 100,000 potential drugs, only one, harmine, drove human insulin - producing beta cells to multiply, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai, funded by JDRF and the National Institutes of Health, and published online in Nature MedicinIn a screen of more than 100,000 potential drugs, only one, harmine, drove human insulin - producing beta cells to multiply, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai, funded by JDRF and the National Institutes of Health, and published online in Nature Medicinin Nature Medicine.

Because the cells inside the droplets are free - floating, the technique allows them to contact each other in every direction, as they would in the human body, rather than only touch side to side as they do in a flat dish.

The researchers showed that cabazitaxel worked better than docetaxel in human prostate cancer cells lines that were resistant hormone treatment, both in terms of slowing cancer - cell growth and in its ability to kill cancer cells.

In humans, as in mice, fat cells of the obese already produced plenty of leptin — more in fact than those of their thin counterparts, since the level of leptin was directly proportional to the amount of faIn humans, as in mice, fat cells of the obese already produced plenty of leptin — more in fact than those of their thin counterparts, since the level of leptin was directly proportional to the amount of fain mice, fat cells of the obese already produced plenty of leptin — more in fact than those of their thin counterparts, since the level of leptin was directly proportional to the amount of fain fact than those of their thin counterparts, since the level of leptin was directly proportional to the amount of fat.

We performed single - cell RNA sequencing in more than 9000 cells to unravel CD4 - CTL heterogeneity, transcriptional profile, and clonality in humans.

When retinal cells die they are much more likely to die in the center of the retina than in the periphery, which the researchers say is exactly what happens in humans with age and the problem with macular degeneration.

The technique's success in the body of an animal (rather than just cells in a petri dish) has Dzau hopeful that he can adapt it to treat humans within a decade.

We have more confidence that we can move toward clinical use of these cells in humans with less concern than we've previously had.»

The mutant far more easily infected human immune cells than did the ancestral pseudotype, the team reports today in Cell.

It was found that complex II activity significantly declined with age, per unit of mitochondria, in the cells derived from the lower rather than the upper levels, an observation not previously reported for human skin.

The scientist tested their set - up using frozen human skin cells, segments of pig heart tissue, and sections of pig arteries in volumes almost 20 times larger than previously attempted samples.

Suspecting that the disease works differently in humans, whose brains are much bigger and more complex than those of lab animals, Brivanlou, along with research associates Albert Ruzo and Gist Croft, developed a cell - based human system for their research.

Gottschling noticed that after about 25 cell divisions — the equivalent of middle age in humans — DNA errors in daughter cells started appearing 100 times faster than normal.

When transplanted into human cells in the laboratory, the mammoth TRPV3 gene produced a protein that is less responsive to heat than an ancestral elephant version of the gene.

In healthy human cells, the p53 protein helps prevent tumors by putting the brakes on the cell cycle to give an ailing cell time to fix itself — or die — rather than spawning more corrupted cells.

Testing the effectiveness of this molecule in their VLP assay, they found that it reduced the ability of the virus to bud off from human cells in culture by more than 90 percent and was similarly effective against proteins found in Ebola and HIV.

Scientists pre-treated human liver cells in vitro with SBEL1 prior to HCV infection and found that SBEL1 pre-treated cells contained 23 percent less HCV protein than the control, suggesting that SBEL1 blocks virus entry.

Rather than artificially triggering cancer by engineering genetic mutations, this model more closely mimics human liver cancer in that tumors develop as a natural consequence of non-alcoholic steatohepatitis (NASH), a chronic metabolic disorder that causes liver damage, fibrosis and numerous cell mutations.

Previous attempts to do the same in monkeys, however, have failed — a disappointment because monkeys are more similar than mice to humans, and thus likely a better harbinger of how stem cell treatments will fare in people.