Sentences with phrase «cells under normal conditions»

The researchers found that the HIV - 1 capsid allows the virus to escape detection by dendritic cells under normal conditions.

Not exact matches

Using a technique known as single - cell RNA sequencing, the team explored more than 65,000 individual cells that exist under normal or inflammatory conditions, looking for genes that were more active in one state or subpopulation versus another.

Under normal conditions, this tail is very important in order to maintain the functioning of nerve cells.

Under normal oxygen conditions, VHL flags the protein for destruction by the cell's protein disposal machinery.

They discovered that even normal, unstressed cells continually produce faulty proteins under respiratory conditions.

In abnormal [PSI +] cells, which are genetically identical to normal cells, the important protein clumps together, and the cells are unable to grow under certain conditions.

The screen turned up some proteins that the Penn team had explored before but also a new one, a protein called BAG3, known as a chaperone protein, which under normal physiological conditions acts to promote cell survival.

Under normal conditions, T - cells and other immune cells collaborate to mount an immune response to invading mycobacteria, ultimately controlling their growth.

In this webinar we will explore how cancer cells are able to reprogram their metabolic pathways to enable energy production under conditions that are disabling to most normal cells.

This study is the first to selectively target ILCs in the presence of an intact immune system, and these findings suggest that under normal conditions, ILCs play a critical role in dampening the anti-bacterial T - cell response using MHCII.

Other researchers caution that it is not yet known whether misfolding occurs under normal conditions in healthy cells.

«Under normal conditions, ECPR plays a crucial role in regulating blood clotting, inflammation, cell death and the permeability of blood vessels.

«In contrast to what's been observed in many studies on foreign proteins and mutant cells, disassembly of native aggregates after heat shock in normal cells is essentially complete under these conditions,» Drummond said.

Under normal conditions, pluripotent frog cells form only skin tissue.

When activated, these cells multiply and then transform into other cell types required to replace worn out cells under conditions of normal tissue maintenance.

But while this is true of normal cells in most unstressed conditions, normal cells also rely on those same pathways to carry them through times when the cell is under stress, and to give them time to recover afterward.

Under normal physiological conditions the number of water molecules entering and exiting an aquaporin - expressing cell is the same, so that the total amount of water in each cell does not change.

Cells were cultured under normal culture conditions for 24 h and the supernatants were subjected to PGE2 ELISA.

Cells from STAT6 DN (a) or STAT6Y641W (b) stable cell lines, corresponding vector controls (V) or parental cells (P) were cultured under normal culture condition and harveCells from STAT6 DN (a) or STAT6Y641W (b) stable cell lines, corresponding vector controls (V) or parental cells (P) were cultured under normal culture condition and harvecells (P) were cultured under normal culture condition and harvested.

Figure 4 shows the mean survival curves obtained with the MTT assay in human umbilical vein endothelial cells (HUVEC), under conditions of normal and low proliferation rates (20 % and 2 % of FBS).

* Acute promyelocytic leukaemia is caused by the modification of two genes, RAR and PML, leading to the development of cancer cells; ** the gene coding for p53 protein plays an essential role in cell proliferation under normal conditions and in maintaining the integrity of the cell genome.

Under normal conditions, so - called checkpoint inhibitor molecules rein in the immune system to ensure that it does not attack the body's own cells, tissues and organs.

In addition to their antioxidant properties, these polyphenolic compounds exhibit neuroprotective properties by their interaction with cellular signaling pathways followed by transcription and translation that mediate cell function under both normal and pathologic conditions.