Sentences with phrase «cells used in the experiments»

On the left side of its results page are things that Semantic Scholar parsed from those papers: not just the typical bibliographic data, such as publication date and author affiliations, but the types of cells used in the experiments and even the methods.

Not exact matches

Whilst acknowledging that many questions remain unanswered in the debate between those who would advocate the use of stem cells taken from human embryos, and those experimenting on stem cells drawn from tissues of the adult human body, there is a lengthy discussion of the moral status of the human embryo as being a crucial matter in this regard.

While other papers have examined these mutations using expensive and time - consuming experiments on live ferrets and laboratory cell cultures, Deem and Melia Bonomo used the pEpitope method to rapidly calculate how much the egg - passage mutations would decrease vaccine efficacy in humans.

Shukla and colleagues discovered that a small drug molecule called BX795, which is sold to labs for use in experiments, helped clear HSV - 1 infection in cultured human corneal cells, in donated human corneas, and in the corneas of mice infected with HSV - 1.

In cellular experiments, live cell imaging was used to monitor VP40 localization in human cellIn cellular experiments, live cell imaging was used to monitor VP40 localization in human cellin human cells.

«Before this study, it was not known if it is possible to produce sufficient numbers of these cells and successfully use them to remuscularize damaged hearts in a large animal whose heart size and physiology is similar to that of the human heart,» said Dr. Charles Murry, UW professor of pathology and bioengineering, who led the research team that conducted the experiment.

Dr. Zubair, medical and scientific director of the Cell Therapy Laboratory at Mayo Clinic in Florida, says the experiment will be the first one Mayo Clinic has conducted in space and the first to use these human stem cells, which are found in bone marrow.

The scientists in London got the same result in a similar experiment using mammalian kidney cells, showing that healthy and mutant cells compete directly against each other in mammals.

A 2017 experiment, also in China, used CRISPR to edit DNA in normal, presumably viable fertilized eggs, or one - cell human embryos.

«The mixtures of cells under debate are called chimeras,» and animal chimeras are used «in a range of developmental biology and stem cell experiments.

Domínguez - Bendala, who led the team along with colleague Ricardo Pastori, found that BMP - 7 caused pancreatic cells to secrete unexpectedly high amounts of insulin after they used it as a control in another, unrelated, experiment.

In the latest experiments the Mitalipov group focused on snipping out the mutated gene in heterozygous cells — a situation in which there was still a «good» nonmutated copy available for the natural cellular repair systems in the embryo to use as a template for repair after the researchers edited out the problematic onIn the latest experiments the Mitalipov group focused on snipping out the mutated gene in heterozygous cells — a situation in which there was still a «good» nonmutated copy available for the natural cellular repair systems in the embryo to use as a template for repair after the researchers edited out the problematic onin heterozygous cells — a situation in which there was still a «good» nonmutated copy available for the natural cellular repair systems in the embryo to use as a template for repair after the researchers edited out the problematic onin which there was still a «good» nonmutated copy available for the natural cellular repair systems in the embryo to use as a template for repair after the researchers edited out the problematic onin the embryo to use as a template for repair after the researchers edited out the problematic one.

B: Well, we were in the midst of experiments aiming to use an animal virus to introduce new genes into human cells and into bacterial cells.

Building on the newly - published pilot study, the team will conduct experiments using a windtunnel which measures the behaviour of mosquitoes towards odours and electrodes which track the response of individual odour - detecting cells from within the antenna of the mosquito in specially - designed secure laboratories at the School to measure the responses of malaria - infected Anopheles gambiae s.s. females to human odours.

Writing in the May 4 online issue of the journal Scientific Reports, researchers at University of California, San Diego School of Medicine used a powerful statistical tool called «design of experiments» or DOE to determine the optimal cell culture formula to grow and produce hPSCs.

The initial experiments made use of cancer cells that Quiñones - Hinojosa and his team removed from willing patients and grew in the laboratory until they formed little spheres of cells, termed oncospheres, likely to be the most resistant to chemotherapy and radiation, and capable of creating new tumors.

Plasmons have been used in wafer - type cells, but Pillai's group is the first to experiment with them in thin films.

In one experiment, they hooked a solar cell to one of the batteries and used solar power to light an LED display.

Cheng and colleagues did experiments using human cells and identified hnRNPM's role in controlling the processes linked to tumor metastasis.

In addition to using normal breast cancer cells in the experiments, the team also used cancer cells that had been genetically engineered to lack either GSTO1 or RYRIn addition to using normal breast cancer cells in the experiments, the team also used cancer cells that had been genetically engineered to lack either GSTO1 or RYRin the experiments, the team also used cancer cells that had been genetically engineered to lack either GSTO1 or RYR1.

Complex phenomena — which we have so far only been able to study in live animals - can now be investigated in simple laboratory experiments using cultivated cells,» says postdoc Hans Christian Cederberg Helms from the Department of Pharmacy.

Collins said that because Hydra is such a simple animal and because it is able to regenerate after complete dissociation into individual cells, it offers researchers the opportunity to use similar techniques as the ones employed in their experiments to examine how an organism develops from an unstructured group of cells into a complex body plan.

After the pig experiment worked well, he used his Boston area facility to culture the 30 million cardiac muscle cells that he says were injected into a heart disease patient in mid-2011.

Once the primary cells are grown in a dish, they quickly stop dividing and can't be used for repeated experiments.

Using in vitro, or test tube, experiments, the researchers applied these chemicals to human cancer cells to measure changes of estrogen receptor - and androgen receptor - target genes and transcriptional activity.

Studies of IBD are typically performed using cell culture experiments or animal models, which don't mimic the precise conditions that occur in the gut of human patients.

In their first set of experiments, Diehl's research team used chemicals to activate the UPR in osteosarcoma cellIn their first set of experiments, Diehl's research team used chemicals to activate the UPR in osteosarcoma cellin osteosarcoma cells.

The final guidelines on research with human embryonic stem cells issued on Monday by the National Institutes of Health set out criteria for determining which ES cell lines can be used in federally funded experiments and give NIH discretion to approve old lines that don't meet stringent modern ethical requirements.

After running the simulations at IU Bloomington, Bacallao confirmed the cyst growth predictions seen in the virtual cysts in experiments using real human cells cultivated from polycystic kidneys from patients at the IU School of Medicine.

The experiment Orwig has in mind is to use gene - editing technology to fix this flaw in the sperm - forming stem cells and then transplant them back into infertile mice, thereby demonstrating a potential treatment for male infertility.

Mindful of public sensitivities, Daley opted to pursue experiments using what he considers the least controversial human materials to create new nonpresidential stem cell lines — poor quality embryos and oocytes that, in his words, «otherwise would have been disposed of as medical waste.»

Previous experiments using stem cells from embryos have shown promise in replacing lost cells, but the use of these is controversial.

There are experiments in using stock market — like systems, in which people bet on ideas to answer seemingly unanswerable questions, like when terrorist events will occur or when stem cell therapy will allow a person to grow new teeth.

The experimental treatment also spared healthy cells, in these and in prior experiments, making the method potentially much less taxing on patients than commonly used chemotherapy.

In experiments using enzyme inhibitors, the possibility that cinnamtannin B - 1 enhanced mobilization through the use of activation of enzymes such as PI3 kinase near the cell membrane was shown.

For experiments aimed at identifying MYC's synthetic lethal partners, such cells may have advantages over the «immortalized» cells commonly used in cancer research, which contain many genetic alterations that make MYC - specific results difficult to discern.

In vitro experiments used human colon carcinoma cells with and without MMP9 and mouse embryonic fibroblasts, which are connective tissue cells that make the extracellular matrix and collagen and play an important role in tissue repaiIn vitro experiments used human colon carcinoma cells with and without MMP9 and mouse embryonic fibroblasts, which are connective tissue cells that make the extracellular matrix and collagen and play an important role in tissue repaiin tissue repair.

In preclinical experiments using human prostate cancer cell lines, Fu's team showed that increased PLK1 expression activated an oncogene known as c - RAF, which has previously been shown to play a role in regulating cell growth and divisioIn preclinical experiments using human prostate cancer cell lines, Fu's team showed that increased PLK1 expression activated an oncogene known as c - RAF, which has previously been shown to play a role in regulating cell growth and divisioin regulating cell growth and division.

But its most immediate use could be to flag mislabeled or contaminated cell lines in cancer experiments, a major reason that studies are later invalidated.

In lab experiments, the research team used cell lines derived from 40 patient tumour samples to identify that CD151 contributes to the survival of cells of high - grade serous ovarian cancer origin.

In addition, the researchers conducted an experiment in the Type I diabetic mice using modified insulin and nanoparticles that had been coated with red blood cell membraneIn addition, the researchers conducted an experiment in the Type I diabetic mice using modified insulin and nanoparticles that had been coated with red blood cell membranein the Type I diabetic mice using modified insulin and nanoparticles that had been coated with red blood cell membranes.

Both Chinese teams used non-viable embryos, but Lovell - Badge says experiments in normal embryos are also important: to see, for instance, whether CRISPR — Cas9 is more or less effective in such cells.

The experiments will also represent the first clinical trials of ES cells under regulations that China adopted in 2015, in an attempt to ensure the ethical and safe use of stem cells in the clinic.

His team have begun recolonising the primate scaffolds with human cells that line blood vessels, the first step towards human - scale biolimb development, and have started experiments using human myoblasts in rats instead of the mice ones.

The experiment shows that precursor cells can develop into functional organs when placed within the body of an adult mammal, says Takebe, who hopes to use the technique to grow organs in nonhuman primates and eventually in humans.

Roein - Peikar also noted that their experiments are mainly based on Chinese Ovary Hamster cells, a cell line derived from the ovary of the Chinese hamster, often used in biological and medical research.

The goal of the first experiment was to see whether lncRNAs are differentially expressed in prostate cancer by measuring total RNA from prostate cancer cell lines and normal epithelial prostatic cells using NCode human ncRNA array and SurePrint G3 human lncRNA microarrays.

A Stanford / SLAC researcher holds the positive electrode from a lithium ion coin cell battery used in experiments.

In experiments to be published Tuesday, July 14, in the journal Nature Communications, the researchers used biochemical and biophysical cues to prompt stem cells to differentiate and self - organize into micron - scale cardiac tissue, including microchamberIn experiments to be published Tuesday, July 14, in the journal Nature Communications, the researchers used biochemical and biophysical cues to prompt stem cells to differentiate and self - organize into micron - scale cardiac tissue, including microchamberin the journal Nature Communications, the researchers used biochemical and biophysical cues to prompt stem cells to differentiate and self - organize into micron - scale cardiac tissue, including microchambers.

Scientists see the term in a more positive light, using animal chimeras in a range of developmental biology and stem cell experiments.