Sentences with phrase «cells used in this study»

«The induced pluripotent stem cells we used in this study proved to be extremely useful in disease modelling, and they could offer an excellent platform for drug discovery and testing new therapeutic targets for Alzheimer's disease in the future,» says Early Stage Researcher Minna Oksanen, the lead author of the study.

He adds that the stem cells used in the study have advantages over reprogrammed skin cells, including eliminating the tricky business of inducing the cells to become muscle cells, but he notes that both types of cells could pose risks because the virus used to modify them could cause cancer.

The authors would like to thank James A. Thomson for providing the human iPS cells used in this study.

Not exact matches

Regarding intensity, a study published in PLOS ONE found that workout intensity was not affected for individuals talking on the phone, compared to those not using a cell phone, but when it came to texting, workout intensity was significantly lower.

A series of preliminary Mayo Clinic studies conducted in 2010 showed promise for the potential use of a chemical component of green tea (epigallocatechin gallate) in reducing the number of cancer cells in patients with chronic lymphocytic leukemia.

Available epidemiologic studies in humans have «not shown clear evidence of a relationship between cell phone use and cancer,» according to the National Cancer Institute, although this remains a topic of debate among researchers.

The majority of study participants reported that it's all good, fine and kosher with them (well, technically «generally OK») to use a cell phone when walking down the street, riding public transit and waiting in line.

Lie4Him, Schweitzer, one of the first scientists to use the tools of modern cell biology to study dinosaurs, has upended the conventional wisdom by showing that some rock - hard fossils tens of millions of years old may have remnants of soft tissues hidden away in their interiors.

Dennis has a PhD in genetics / developmental biology from the University of British Columbia and a special interest in studying pattern formation and cell - cell communication during tissue development using fruit flies as a model organism.

High dosages of reb A fed to rats reduced sperm production and increased cell proliferation in their testicles; however, another study using rats and humans demonstrated lack of reproductive toxicity.

While our work has used mouse models because we can study the process in detail this way, we do know that milk cells cross into human babies as well.»

This allowed them to track changes in calcium ion concentrations in the cells around wounds in living tissue (as opposed to the cell cultures used in many previous wound response studies) and to do so with an unprecedented, millisecond precision.

In a study in the journal Science, researchers explain how they used mouse embryonic stem cells and microchip technology to create heart muscle tissue that actually beatIn a study in the journal Science, researchers explain how they used mouse embryonic stem cells and microchip technology to create heart muscle tissue that actually beatin the journal Science, researchers explain how they used mouse embryonic stem cells and microchip technology to create heart muscle tissue that actually beats.

Eighth Place: Skyler Jones, 17, of Ossining, N.Y., received a $ 60,000 award for her study of perovskite crystals used in solar cells.

«Visualizing atoms of perovskite crystals: Researchers conduct the first atomic resolution study of perovskites used in next generation solar cells.»

Easy - to - grow «HeLa» cells have been used in more than 76,000 studies.

A related paper, involving Svendsen, his colleague Gad Vatine, PhD, and a team from University of California, Irvine, published the same day in the journal Cell Reports, used a similar approach to study Huntington's disease.

Immunophenotyping — a laboratory procedure used to study the proteins expressed by cells — is very commonly used in basic science research as well as in laboratory diagnostic testing.

«There was this initial thought that [circulating tumor cells] are only present at late stage,» says Sollier - Christen, but she notes that in the past year, several studies using more sensitive techniques have found such cells much earlier in tumor development, even before the tumor becomes visible by conventional imaging techniques.

«To our knowledge, we are the only research group to use sequential human biopsies to study CD8 + T cell function in situ, in their natural spatial distribution and at their original physiological state,» she said.

In the present study, the researchers have discovered a reason for reduced fertility in people with autoimmune polyendocrine syndrome type 1 (APS1), which increases the risk of developing autoimmune disease (caused by the immune system attacking and damaging healthy cells) and which is often used as a model for autoimmune disease in generaIn the present study, the researchers have discovered a reason for reduced fertility in people with autoimmune polyendocrine syndrome type 1 (APS1), which increases the risk of developing autoimmune disease (caused by the immune system attacking and damaging healthy cells) and which is often used as a model for autoimmune disease in generain people with autoimmune polyendocrine syndrome type 1 (APS1), which increases the risk of developing autoimmune disease (caused by the immune system attacking and damaging healthy cells) and which is often used as a model for autoimmune disease in generain general.

Snyder and his team have since studied many of the proteins in that network that interact with NO, including GAPDH, a protein best known for regulating how cells store and use sugars.

In the meantime, researchers could use the cells to study neurological and psychiatric disorders in Petri disheIn the meantime, researchers could use the cells to study neurological and psychiatric disorders in Petri dishein Petri dishes.

Scientists use cell reprogramming techniques to produce cells in the lab so that they can study diseases.

Richard Jones, M.D., professor and director of the Bone Marrow Transplant Program at Johns Hopkins, developed a now commonly used assay to study ALDH levels in individual cells.

Large quantities of these reverted cells could be used to treat anything from spinal cord injury to liver damage without the risk of tissue rejection, said Robert Weinberg, a biologist at the Massachusetts Institute of Technology's Whitehead Institute for Biomedical Research and co-author of a study appearing in Cell.

The study results were found using mouse embryonic stem cells, which are good cell models for the study of processes seen in human stem cells.

Combing the genetic data from a transmission study in ferrets, a team led by Thomas Friedrich, a professor of pathobiological sciences at the University of Wisconsin - Madison School of Veterinary Medicine, found that during transmission, when one animal is infected by another through sneezing or coughing, the process of natural selection acts strongly on hemagglutinin, the structure the virus uses to attach to and infect host cells.

A new study has identified a group of molecules in prostate - cancer cells that doctors might one day use to distinguish which patients should be treated with radiation therapy if rising PSA levels indicate their cancer has recurred after surgical removal of the prostate.

«Cultural revolution in the study of the gut microbiome: Human gut - on - a-chip technology used to co-culture gut microbiome, human intestinal cells could lead to new therapies for inflammatory bowel diseases.»

In preclinical studies using cell models that mimicked liver cells of patients with the rare disease Friedreich's ataxia (FA), a widely used cholesterol - lowering drug increased a precursor of HDL (high - density lipoprotein), the «good cholesterol,» according to new research published in PLOS ONE from the Perelman School of Medicine at the University of PennsylvaniIn preclinical studies using cell models that mimicked liver cells of patients with the rare disease Friedreich's ataxia (FA), a widely used cholesterol - lowering drug increased a precursor of HDL (high - density lipoprotein), the «good cholesterol,» according to new research published in PLOS ONE from the Perelman School of Medicine at the University of Pennsylvaniin PLOS ONE from the Perelman School of Medicine at the University of Pennsylvania.

Protein expression in these glioblastoma cells more closely mimicked that in real cancer cells than in 2D cultures of cells, indicating that this method could be used to study cancer (Nature Nanotechnology, DOI: 10.1038 / nnano.2010.23).

«Before this study, it was not known if it is possible to produce sufficient numbers of these cells and successfully use them to remuscularize damaged hearts in a large animal whose heart size and physiology is similar to that of the human heart,» said Dr. Charles Murry, UW professor of pathology and bioengineering, who led the research team that conducted the experiment.

Dr Claudia Wellbrock, study author and Cancer Research UK scientist at The University of Manchester and a member of the Manchester Cancer Research Centre, said: «We used to think that cancer cells spread by first specialising in invading other parts of the body and then change in order to grow rapidly.

Now a University of Colorado Cancer Center study published online ahead of print in the journal Oncogene offers compelling evidence explaining this failure and offering a possible strategy for the use of retinoic acid or other retinoids against some breast cancers: Because early clinical trials are often offered to patients who have already tried other more established therapies, breast cancer cells may have been pushed past an important tipping point that offers retinoic acid resistance.

This proof - of - principle study shows «for the first time... that human iPS cells can be used to model a diverse range of inherited diseases in adult cells,» the authors wrote in their paper, published online in The Journal of Clinical Investigation August 25.

«Our studies suggest that the local auxin signals can be communicated over long distances using calcium waves in order to generate an auxin signal also in target cells located far away,» Hedrich says.

In addition, the substance used to stick cells together (ViaGlue), will provide researchers with tools to create and test 3D in vitro cardiac tissue in their own labs to study heart disease and issues with transplantatioIn addition, the substance used to stick cells together (ViaGlue), will provide researchers with tools to create and test 3D in vitro cardiac tissue in their own labs to study heart disease and issues with transplantatioin vitro cardiac tissue in their own labs to study heart disease and issues with transplantatioin their own labs to study heart disease and issues with transplantation.

To more accurately reflect the mechanisms driving oligodendrogliomas, the researchers used RNA sequencing to study directly, on a single - cell level, gene expression in samples from six early - stage human tumors.

Ours is the first study to rebuild the native tracks and gaps that exist in tissue to investigate how cells use these as superhighways to move quickly to spread throughout the body,» says Reinhart - King.

In this study, the researchers took a two - pronged approach, using human cells and tissue.

The plant compounds used by the UGA researchers — resveratrol, found in grapes; genistein, found in soybeans; and quercetin, found in apple peels and onions — have all been shown in previous studies to be fat - busters, causing fat cells to burst and release their contents.

In this study, the research team used a new technique developed at the University of North Carolina to study a type of glial cell known as an astrocyte.

In this study, the Hiroshima University researchers developed an animal model using severely immunodeficient mice whose livers were partially populated with human cells, in order to reconstruct elements of the human immune systeIn this study, the Hiroshima University researchers developed an animal model using severely immunodeficient mice whose livers were partially populated with human cells, in order to reconstruct elements of the human immune systein order to reconstruct elements of the human immune system.

The result was the largest deletion ever observed in the dystrophin gene using CRISPR / Cas9, and the study was the first to create corrected human iPS cells that could directly restore functional muscle tissue affected by Duchenne.

«Due to the inhibitory function of Treg cells, people have been trying to use these cells for therapy in human autoimmune diseases or transplantation,» explains professor Yun Cai Liu, Ph.D., who led the current study.

And while cytochalasin D might not be the actual agent scientists use to trigger bone formation in the clinic, Rubin's study shows that triggering actin transport into the nuclei of cells may be a good way to force mesenchymal stem cells to become bone cells.

«Using this technology, the study is the first to discover the critical role of astroglial cells in Down syndrome as well as identify a promising pathway for exploring how a drug such as minocycline may offer an effective way to help treat it.»

While mouse models have traditionally been used in studying the genetic disorder, Deng said the animal model is inadequate because the human brain is more complicated, and much of that complexity arises from astroglia cells, the star - shaped cells that play an important role in the physical structure of the brain as well as in the transmission of nerve impulses.

In a new study, Murphy, a molecular biologist at Princeton University, showed that long - lived bodily, or somatic, cells in Caenorhabditis elegans, a one - millimeter nematode commonly used as a model for aging studies in labs, activate genetic pathways completely separate from those found in long - lived egg, or oocyte, cellIn a new study, Murphy, a molecular biologist at Princeton University, showed that long - lived bodily, or somatic, cells in Caenorhabditis elegans, a one - millimeter nematode commonly used as a model for aging studies in labs, activate genetic pathways completely separate from those found in long - lived egg, or oocyte, cellin Caenorhabditis elegans, a one - millimeter nematode commonly used as a model for aging studies in labs, activate genetic pathways completely separate from those found in long - lived egg, or oocyte, cellin labs, activate genetic pathways completely separate from those found in long - lived egg, or oocyte, cellin long - lived egg, or oocyte, cells.