The study assessed biomarkers of inflammation, microbial translocation, and
cellular activation in a cohort of Ugandan HIV - 1 seroconverters to understand their relationship to disease progression.
Not exact matches
Plans start as low as $ 6.95 / mo and are selected at
activation in the Whistle app (no separate
cellular contract required).
«
In contrast to RNA interference, which is commonly used to inactivate gene activity, the CRISPR - on system allows
activation of
cellular genes.
The results suggest the simultaneous
activation of certain molecular pathways — actions among molecules
in a cell that can lead to change —
in particular the MAPK and PI3K
cellular pathways, triggered tumor initiation and produced increasingly dense low - grade gliomas that quickly progressed to glioblastoma multiforme (GBM).
The analysis also showed that the preponderance of host responses shifted rapidly from
activation of genes involved
in cell damage and inflammation toward those linked to promotion of
cellular and organ repair.
«While several lipid families are well - characterized at the molecular level, the total diversity and number of unique lipids
in cells, how they change during
cellular activation, and how they differ
in individuals is unknown,» said Darley - Usmar.
In our laboratory, we are interested in both the cellular and the molecular events that lead to the activation of B cell
In our laboratory, we are interested
in both the cellular and the molecular events that lead to the activation of B cell
in both the
cellular and the molecular events that lead to the
activation of B cells.
It would seem, therefore, that
cellular division has at least one significant negative control component
in both rabbit and human corneal endothelial cells whose
activation may be delayed.
Bradley MN, Hong C, Chen M, Joseph SB, Wilpitz DC, Wang X, Lusis AJ, Collins A, Hseuh WA, Collins JL, Tangirala RK, Tontonoz P. Ligand
activation of LXR beta reverses atherosclerosis and
cellular cholesterol overload
in mice lacking LXR alpha and apoE.
The lab's findings
in the study, «D - serine Deficiency Attenuates the Behavioral and
Cellular Effects Induced by the Hallucinogenic 5 - HT2A Receptor Agonist DOI,» suggested that D - serine - dependent NMDAR activity is involved
in mediating the
cellular and behavioral effects of 5 - HT2AR
activation.
The
cellular transcription factor NF - kB consists of two DNA - binding subunits of 50K and 65K and is believed to play an important role
in stimulating transcriptional
activation of HIV - 1
in latently infected T - cells
Inhibition of c - Abl with STI571 attenuates stress - activated protein kinase
activation and apoptosis
in the
cellular response to 1 - β - d - arabinofuranosylcytosine.
Rituximab is thought to function through
activation of natural killer cells, resulting
in cellular cytotoxicity.
In particular, the cAMP signaling cascade directs adaptive
cellular responses to a variety of stress stimuli via a combination of acute affects arising from GS - protein coupled receptor (GPCR)- mediated
activation of PKA and long - term affects resulting from transcriptional reprogramming directed by CREB and the CREB Regulated Transcription Coactivators (CTRCs).
Whitehead Institute scientists report that the gene mutated
in the rare hereditary disorder known as Birt - Hogg - Dubé cancer syndrome prevents
activation of mTORC1, a critical nutrient - sensing and growth - regulating
cellular pathway.
Topics such as the mechanisms of cell injury
in normal and dystrophic muscle, compensatory muscle regeneration and hypertrophy, and the effects of various therapies or voluntary exercise on muscle repair, satellite cell
activation, muscle growth, bone density and age - related atrophy are examined using a large variety of
cellular, molecular and whole - animal
in vivo assays of function.
This study is the first to investigate the phenotypic effects of the HAT activator CTPB, and to demonstrate that p300 / CBP HAT
activation has neurotrophic effects
in a
cellular model of PD.
In response to cellular stress such as DNA damage, oncogene activation, transcriptional inhibition, and hypoxia, tumor suppressor p53 is activated and expressed, and acts as a transcription factor to induce its target genes [1], thereby playing a central role in the regulation of DNA repair, cell cycle, apoptosis, senescence, and angiogenesis [2 - 4
In response to
cellular stress such as DNA damage, oncogene
activation, transcriptional inhibition, and hypoxia, tumor suppressor p53 is activated and expressed, and acts as a transcription factor to induce its target genes [1], thereby playing a central role
in the regulation of DNA repair, cell cycle, apoptosis, senescence, and angiogenesis [2 - 4
in the regulation of DNA repair, cell cycle, apoptosis, senescence, and angiogenesis [2 - 4].
Stress resistance has not been assessed however and so the biological relevance of this finding is currently unknown.32 Several IER trials (75 - 85 % ER on restricted days)
in overweight / obese populations have reported reductions in various markers of oxidative stress 37, 41, which in one study was accompanied by a complementary increase in the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directio
in overweight / obese populations have reported reductions
in various markers of oxidative stress 37, 41, which in one study was accompanied by a complementary increase in the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directio
in various markers of oxidative stress 37, 41, which
in one study was accompanied by a complementary increase in the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directio
in one study was accompanied by a complementary increase
in the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directio
in the anti-oxidant uric acid.37
In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directio
In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy
in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directio
in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months)
in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directio
in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease
in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directio
in the IER group and increase
in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directio
in the CER group which the authors proposed may have resulted from IER - induced
activation of autophagy, a key homeostatic
cellular process
in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directio
in which dysfunctional or unnecessary
cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions
in AOPP in both groups after three months.48 Summary and Future Research Directio
in AOPP
in both groups after three months.48 Summary and Future Research Directio
in both groups after three months.48 Summary and Future Research Directions
Twelve - hour exposure of 3T3 - L1 adipocytes to H (2) O (2) or TNF - alpha resulted
in the increase of c - Jun NH (2)- terminal kinase (JNK)
activation and insulin receptor substrate 1 (IRS1) serine 307 phosphorylation, concomitantly with the decrease
in insulin - stimulated IRS1 tyrosine phosphorylation and
cellular glucose uptake.
A leukocyte
activation test identifies food items which induce release of DNA by innate immune peripheral blood leucocytes Irma Garcia - Martinez, Theresa R. Weiss, Muhammad N. Yousaf, Ather Ali † and Wajahat Z. Mehal † † Contributed equally Published
in BioMedCentral, Nutrition and Metabolism View Publication Abstract Background Leukocyte
activation (LA) testing identifies food items that induce a patient specific
cellular response
in the immune system,...
In our case, we got through to an OnStar assistant within 5 seconds of pressing the roof - mounted activation button, told the nice lady where we wanted to go, and waited a further 10 seconds after hanging up as the directions found their way over a cellular network to our car's in - dash head uni
In our case, we got through to an OnStar assistant within 5 seconds of pressing the roof - mounted
activation button, told the nice lady where we wanted to go, and waited a further 10 seconds after hanging up as the directions found their way over a
cellular network to our car's
in - dash head uni
in - dash head unit.
That it borders on being over the top
in electronic complexity was not entirely avoidable given the long list of features, including a hands - free, built -
in cellular phone with voice
activation and quick links to emergency and roadside help; a navigation system; a premium stereo; and dual zone automatic climate control - all of which have come to be expected
in the ultraluxury class.
Axing the iPad mini
in favor of a large iPhone would not only refocus Apple's tablet line - up but encourage
cellular activations among those switching a small slate for a big smartphone.