Sentences with phrase «cellular aging process»

Antioxidants will slow the cellular aging process.

Pulmonary fibrosis can possibly be attributed to a kind of cellular aging process, which is called senescence.

«The effects observed in this study may be part of larger PTSD - related accelerated cellular aging process that is manifested in premature health decline,» she said..

Counteracting the telomere shrinking process is the enzyme, telomerase, that uniquely holds the key to delaying or even reversing the cellular aging process.

The sense of smell may be linked to the cellular ageing process in many other organisms — even people.

Not exact matches

Now 24, he is a first - year graduate student in the department of cellular and structural biology at the University of Texas Health Science Center in San Antonio (UTHSCSA), where he is studying the role of oxidative damage — the wear and tear inflicted upon the cell by toxic molecules called free radicals — in the aging process.

Izpisua Belmonte added that more extensive studies will be needed to fully understand the role of heterochromatin disorganization in aging, including how it interacts with other cellular processes implicated in aging, such as shortening of the end of chromosomes, known as telomeres.

«What we're seeing is a normal process — cellular aging — augmented and accelerated once a cell becomes cancerous.

The drug targets a specific cellular process that occurs in animals, including humans, delaying the onset of age - related deaths by slowing the aging process.

But with age, the balance tips, as mitochondria and other cellular processes produce excess free radicals and the body's antioxidant defenses can't keep up, Rossman said.

One likely place to look for an answer was histones, to see if changes in the patterns of the chemical marks on them might reveal any secrets, at the cellular level, of the aging process we all experience — and, perhaps, whether there might be anything we can do about it.

LA JOLLA — A study tying the aging process to the deterioration of tightly packaged bundles of cellular DNA could lead to methods of preventing and treating age - related diseases such as cancer, diabetes and Alzheimer's disease, as detailed April 30, 2015, in Science.

While normal RNA regulation involves regulated and reversible assembly of RNA - protein particles, both increased cellular age and mutation push the process towards hyperassembly, which leads to altered pools of RNA or RNA regulatory proteins in neurons that contribute to their eventual death.

It has previously been shown to activate a cellular process known as autophagy, which protects against aging by enabling cells to degrade and discard old, damaged «cellular garbage» before it damages cells.

For setting cancer in the context of ageing tissue, study of normal adult homeostasis is important — we are studying mutational processes, clonal dynamics and cellular competition in thousands of non-cancerous cells and samples from a range of tissue types, in health and disease.

LAMP2A: The A variant of lysosome - associated membrane protein 2 is a receptor involved in the cellular maintenance processes of autophagy, but levels decrease with age, and in at least some species this appears to be one of the factors involved in the age - related decline of autophagy.

Part of this is a pathological redistribution of adipose from the subcutaneous to the visceral depot, but it now emerges that the subcutaneous depot becomes qualitative as well as quantitatively abnormal in the degenerative aging process also suffers genuine age - related lipoatrophy and lipodystrophy — and that p16Ink4a - driven cellular senescence is at the heart of it.

AD, PD, and other diseases and functional deficits of degenerative aging processes emerge from the ongoing and often mutually - reinforcing accumulation of multiple forms of cellular and molecular damage.

Chung and Khurana used the wealth of data from the yeast alpha - synuclein toxicity model to clue them in on key cellular processes that became perturbed as patient neurons aged in the dish.

For his 2013 SENS Research Foundation Summer Internship, Ethan joined the laboratory of Dr. Judith Campisi at the Buck Institute for Research on Aging to study cellular senescence, the process by which damaged cells enter irreversible growth arrest.

(9) Indeed, the degenerative aging process is by definition one in which the organism progressively accumulates damage to its cellular and molecular components over time, so any genetic or environmental factor that leads to a greater burden of such damage will bear some resemblance to the aging phenotype, irrespective of the causal origin of the defect or its relationship to «normal» aging.

The biological process of cellular senescence represents an ideal paradigm to examine the role of the DNA damage response, epigenetically determined chromatin structure, and metabolic reprogramming during tissue aging and cancer development.

Using replicative senescence as a cellular model, we will dissect the functions of ATR and ATM in the process of aging and in premature aging diseases.

We present the literature on pathophysiological processes that may hasten aging and its relevance to addiction, including: oxidative stress and cellular aging, inflammation...

Human cells undergo a process called cellular aging that limits the number of times they can divide, thereby setting the self - renewal capacity of human tissues.

LA JOLLA — A study tying the aging process to the deterioration of tightly packaged bundles of cellular DNA could lead to methods of preventing and treating age - related diseases such as cancer,...

Here are some of the compelling findings on cognitive ability, gut health and immunity, telomere lengthening, cellular homeostasis and longevity — all processes that, if optimized, can result in graceful aging.

The ability to measure the degree of cellular senescence is important in understanding the biological processes regulating cell aging and immortalization.

In order to accelerate the development of therapies to bring aging under full medical control, the Forever Healthy Foundation directly supports cutting - edge research aimed at the molecular and cellular repair of damage caused by the aging process.

How do changes on a cellular level contribute to adaptation processes that allow the brain (and with it its owner) to age successfully?

What's fascinating, though, is that exercise may actually work on a cellular level to reverse the toll of stress on our ageing process.

A comforting mug of rooibos helps combat harmful oxidation — a process linked to cellular aging and disease — thanks to its generous amount of free radicals.

Most recently, Spanish researchers publishing in the journal Molecules reported that the various components of olive oil including oleic acid and secoiridoids protect your body on the cellular level to slow the aging process.

These anti-aging products also include antioxidant rich formulas that address aging on a cellular level for a wide range of aging processes and support functions such as joint, cognitive, and skin health.

This is a way of slowing down the aging - related processes, improves brain functioning and memory capacity, strengthens and stabilizes cellular membranes which is crucial for cell signaling and energy transfer.

Oxidative stress is harmful to the body at a cellular level, so much so that it is thought to be a central factor in the aging process itself.1 These suppositories contain epigallocatechin -3-gallate (EGCG), known for being one of the most potent catechins present in green tea.2

Over the course of your lifetime free radical damage tends to accumulate, and scientists theorize that this accumulated damage contributes to cellular dysfunction and ultimately to declining health as we age, and is thought to be a significant part of the aging process itself.

Besides increasing lipolysis or fat - burning, lowering insulin levels also greatly increases the rate of autophagy, the cellular self - cleansing process that rids cells of junk and that is so important to fighting aging.

Glycated proteins and cellular structures have altered function, increased vulnerability to oxidative damage, and reduced degradation and clearance.6 Slowing the entry of glucose into the brain would delay these processes and possibly give the body's defenses more time to dispose of the AGEs.

Studies show that while eggs, processed meat, poultry and fish may accelerate cellular aging, plant - based diets promote telomere protection, something for which drugs can not complete.

* This important antioxidant neutralizes free - radicals which cause cellular damage in the body and contribute to the aging process.

This sets off a chain reaction of imbalance and damage at the cellular level referred to as oxidative stress - a condition thought to be a core factor in the aging process itself!

So fasting may actually reverse the entire aging process by getting rid of old cellular junk and replacing it with new parts.

This slows down the aging process on a cellular level and mitigates damage.

Aging processes are partly due to cellular rusting.

Where some may think the word vegetable is a good thing, the majority of commercial oils are highly processed damaging oils (including the majority of commercial olive and grape seed oils) that take the place of good fats in your body, damaging all over health on a cellular level, including skin cells, which speeds up the aging process!

The progressive demethylation of DNA (largely due to toxin exposure) is one of the primary drivers of the aging process and eventually leads to cellular and metabolic dysfunction.

Supplementation with nicotinamide mononucleotide can slow cellular aging and improve many metabolic defects common to degenerative processes, including diabetes, declining heart function and neurodegenerative conditions.

Chlorella has very high levels of nucleic acids (DNA and RNA), which help regulate gene activity, cellular function, detoxification, and is very effective in slowing down the aging process through supporting cellular repair.

Studies show that nicotinamide mononucleotide supplementation can slow cellular aging and improve many of the metabolic defects common to the aging process, including obesity, diabetes, cardiovascular disease, and neurodegenerative conditions.