Sentences with phrase «cellular and molecular mechanisms»

Our laboratory uses in vivo and in vitro techniques to understand the physiological, cellular and molecular mechanism of metabolic therapies.

A research team from Wayne State University recently published a paper in the Journal of Clinical Investigation that provides a paradigm shift in the understanding of cellular and molecular mechanisms underlying diabetic peripheral neuropathy (DPN) and wound healing in the treatment of corneal and skin diabetic ulcers.

Fortier Laboratory Dr. Lisa Fortier's laboratory investigates the underlying cellular and molecular mechanisms involved in the development of arthritis with the goal of identifying finding new ways to treat and prevention arthritis.

In parrallel, we are also using these stem cells to investigate cellular and molecular mechanisms of HGPS.

Using these techniques, Dr. Watanabe is studying cellular and molecular mechanisms underlying synaptic transmission and synaptic plasticity.

Dr. Israelson's lab focuses on cellular and molecular mechanisms that lead to the onset and progression of neurodegenerative diseases, such as Alzheimer's, Parkinson's and Huntington's diseases, with special emphasis on ALS.

Eugeniu Nacu (Tanaka, TUD)-- «Understanding cellular and molecular mechanisms of regeneration in Ambystoma mexicanum (axolotl)» (2011)

Neurodegenerative diseases are increasingly being realized to have common cellular and molecular mechanisms including protein misfolding and aggregation.

There has been much attention given to the environmental conditions that trigger a reef's demise due to bleaching, but little is certain about the precise cellular and molecular mechanisms of the bleaching process.

The long - term goal of our studies is to understand the complex cellular and molecular mechanisms of inter - and intra-cellular communication in the immune system.

Thomas Jessell has defined key cellular and molecular mechanisms that control the development and functional organization of the spinal cord.

We are also exploring the potential cellular and molecular mechanisms anchoring mitochondria at presynaptic boutons.

They've also researched exactly which cellular and molecular mechanisms Zika uses to get across the placental barrier and then to infect fetal cells.

Cancer hijacks the immune system by various cellular and molecular mechanisms and dysfunction of immune system arises during the early stages of cancer and throughout progression to later aggressive stages.

So does DivIDe, which will train a new generation of molecular engineers endowed with a strong basis in quantitative computational and biochemical methods, and therefore capable of addressing cellular and molecular mechanisms.

Therefore, the identification of cellular and molecular mechanisms underlying neuron - astrocyte communication will help to a better understanding of the mechanisms of brain phsyiology as well as to appropriately identify cellular targets to direct therapeutic approaches for the future treatment of several brain diseases.

We investigate cellular and molecular mechanisms of retinal degeneration and regeneration using rodents and human cells as model systems.

Cédric Blanpain, MD / PhD, WELBIO investigator, and Professor at the Université libre de Bruxelles, Belgium, defined the cellular and molecular mechanisms that regulate wound healing in the skin.

It's been a big challenge to try to find a target for cGVHD therapies, because of the more complex immune reaction in cGVHD and the fact that its cellular and molecular mechanisms are not as well understood.»

The Hsieh lab studies the cellular and molecular mechanisms of neurogenesis to understand how stem cells become mature, functioning nerve cells, and how aberrant neurogenesis contributes to seizure formation, an unwarranted side effect of neuroregenerative strategies.

«While more work is required to elucidate the cellular and molecular mechanisms through which B cells exert their beneficial function in wound healing, we are in the process of obtaining the required regulatory approvals to conduct a first clinical study in patients with diabetic foot ulcers.

Unlike steroids, lipoxins are a family of specialized pro-resolving mediator, a class of endogenous molecules that is being investigated to determine their capacity to resolve inflammation as well as their cellular and molecular mechanisms for resolution.

USC researchers have uncovered the cellular and molecular mechanisms behind tooth renewal in alligators.

The authors uncover the cellular and molecular mechanisms, as well as the gene network regulated by Sox9 during the early steps of skin tumor initiation and demonstrates that Sox9 controls the long term maintenance and expansion of oncogene expressing cells by promoting self - renewing division and inhibiting differentiation.

Research at CNIC is aimed at identifying the cellular and molecular mechanisms underlying the origin and evolution of cardiovascular illnesses.

-- The cellular and molecular mechanisms by which one neuron finds specific target neurons and eventually forms functional sub networks are not fully understood.

The first aims to define the cellular and molecular mechanisms governing metastases growth and spread within the liver, a preferential area of metastatic dissemination of tumors of different origin (colorectal, pancreas, lung and breast) often associated with poor prognosis, mostly because of late diagnosis and / or relative inefficiency of current available anti-tumoral drugs.

Prof. Nicoll's lab is interested in elucidating the cellular and molecular mechanisms underlying learning and memory in the mammalian brain.

Research programs of Immunopathology Unit aim to dissect the cellular and molecular mechanisms responsible for immunopathological responses of the liver, with emphasis on the responses that occur during infection with hepatitis B virus (HBV).

Research in our laboratory focuses on the cellular and molecular mechanisms of action of substances of abuse and their interaction with neurotransmitter systems.

I have established research interests in the cellular and molecular mechanisms regulating the development and function of the testes and which influences spermatogenesis.

Our lab is interested in identifying the cellular and molecular mechanisms involved in the organization and maintenance of the synapse with a specific focus on the control of neurotransmitter receptor expression and localization.

Her group is particularly interested in the cellular and molecular mechanisms which control lung epithelial stem cell fate decisions.

These findings open up the possibility of augmenting cardiac and neuronal regeneration if the underlying cellular and molecular mechanisms can be revealed.

The team currently is exploring the cellular and molecular mechanisms underlying ischemic preconditioning using mice in which HIF - 1 activity has been knocked out in specific cell types within the heart.

I - What are the cellular and molecular mechanisms patterning the connectivity of cortical circuits during mammalian development?

Our work provides new insights into the cellular and molecular mechanisms underlying the establishment and maintenance of brain connectivity and has significant implications for our understanding of the pathophysiological mechanisms underlying socially - devastating neurodevelopmental disorders and neurodegenerative diseases.

Royet will present his latest data dissecting the cellular and molecular mechanisms by which one single microbiota - derived compound, peptidoglycan, influences the behavior, the physiology, and the homeostasis of its infected host.

The goal of our research is to better understand the cellular and molecular mechanisms involved in neuronal and synaptic dysfunctions characterizing neuropsychiatric diseases.

However, our understanding of the cellular and molecular mechanisms patterning the connectivity of these classes of neurons is still limited.

She also investigates the cellular and molecular mechanisms of innate and adaptive immune responses by RNA vaccines.

In particular, we plan to study the cellular and molecular mechanisms underlying inflammatory cell recruitment to the adipose tissue in the course of obesity and in diabetes mellitus.

She investigates the cellular and molecular mechanisms of innate and adaptive immune responses observed following immunization in mouse models.

Teniel S. Ramikie, PhD, is a research fellow in the laboratory of Dr. Kerry Ressler and her research interests include investigating the cellular and molecular mechanisms driving the pathophysiology of psychiatric disease states.

This understanding of the cellular and molecular mechanism of recovery from acute promyelocytic leukaemia opens prospects for activating this same PML / p53 pathway in other types of cancers.

We are currently dissecting the cellular and molecular mechanisms underlying CIN - induced tumor growth, metastatic behavior and malignancy.

My lab uses the wing imaginal disc to dissect the cellular and molecular mechanisms underlying the regulation of tissue growth.

His laboratory focuses on the cellular and molecular mechanisms of cancer progression.

In this regard, we are dissecting the cellular and molecular mechanisms underlying the homeostatic capacity of the tissue to several insults (with a special interest in genomic instability) and its potential impact in tumorigenesis.