However, if cortisol is chronically elevated by sustained stressors as seen in sustained or frequent boredom, there are measurable consequences in
cellular brain changes.
Not exact matches
We are now beginning to understand some facets of human emotionality, decision - making, morality, trauma and the drive for political power down to the
cellular level, by observing
changes in neurochemistry, neural pathways, and neuro - anatomical transformations in the
brain.
It is critical for physicians to monitor these secondary tissue damages, as they are frequently the origin of significant long - term effects, including
brain damage, cognitive deficits, psychosocial / behavioral / emotional
changes, bodily damage and biochemical
changes at the
cellular level.
He hypothesized that
changes can occur at the
cellular level within the
brain and may be related to myelination, the process of building the protective sheath around the nerves.
«We have successfully used cinnamon to reverse biochemical,
cellular and anatomical
changes that occur in the
brains of mice with poor learning,» Pahan said.
In the past decade, researchers have used mouse models to unravel how
cellular changes in the nucleus accumbens (NAc), a
brain structure involved in action selection associated with arousal and reward, may contribute to addiction - related behavior.
Repeatedly drinking to intoxication leads to
cellular adaptation within the
brain,
changing the sensitivity to alcohol.
To the researchers» surprise, the mice subjected to both prenatal infection and stress during puberty showed far greater behavioral deficits and
cellular changes in
brain regions relevant to schizophrenia than those that had been exposed to infection or stress alone.
Now, a team of NIH - funded scientists has identified a potential drug that could grant the same resilience to the
brains of ischemic stroke patients by mimicking the
cellular changes that protect the
brains of those animals.
Dr. Chartoff is interested in how chronic exposure to drugs of abuse
changes the
brain at molecular and
cellular levels such that drug withdrawal elicits a protracted constellation of negative affective signs.
Research The acute phase response and soman - induced status epilepticus: temporal, regional and
cellular changes in rat
brain cytokine concentrations.
The George lab has made seminal contributions to the field including: discovering a novel population of neurons in the
brain of humans, rats and mice that are involved in nicotine dependence, identifying neuronal ensembles responsible for nicotine and alcohol addiction, and unveiled the
cellular and molecular
changes associates with long term use of nicotine, cocaine, methamphetamine and alcohol use on the
brain.
Kinney is seeking to understand
cellular and molecular
changes in the
brain that underlie these disorders.
How do
changes on a
cellular level contribute to adaptation processes that allow the
brain (and with it its owner) to age successfully?
Dr. Bateman said: «Within three years this project will dramatically increase our understanding of the molecular and
cellular changes that occur in the
brain in TSC.»
Not only do
cellular changes within the muscle contribute to fatigue, but there is increasing evidence that the
brain has a major effect on an athlete's perception of fatigue.
''... we hypothesize that repeated stress - related allostatic overload may affect
brain function at three basic levels: (a) at the
cellular level, it may compromise proteostasis (e.g. tau protein), organelles homeostasis, and induce epigenetic
changes in neuronal DNA; (b) at the tissue level it may affect intracellular communication (synaptic contacts), number of cells (reduction of neuronal density), composition of the extracellular matrix (accumulation of amyloid plaques), and neuroinflammation; (c) at the systemic levels it may alter the
brain's regulation of behavior (cognitive decline).
All of the
brain training and cognitive stuff that I worked on, the same exact statement about when you
change something at the
cellular level.