Sentences with phrase «cellular composition change»
To find out why, computational biologists came up with a computer model to predict how microbial metabolism and cellular composition change as cell size varies, using details about how much space a bacterium needs for its components — DNA, proteins, and the molecular factories called ribosomes — to function.
http://www.sciencemag.org/ Not exact matches
Dynamic changes of membrane composition and organization are crucial for key cellular processes.
We found significant differences in overall cellular composition between pre - and post-mortem blood samples (p < 0.001), the most notable changes induced by death being an increase in resting NK cells and CD8 T - cells, and a substantial reduction in neutrophils (Fig. 7a).
The transcriptional changes detected above may partially be related to changes in the cellular composition of blood triggered by death.
The researchers found that loss of collagen VII not only affected the composition of the cellular microenvironment but also led to global changes in cell homeostasis on mRNA and on protein level.
''... we hypothesize that repeated stress - related allostatic overload may affect brain function at three basic levels: (a) at the cellular level, it may compromise proteostasis (e.g. tau protein), organelles homeostasis, and induce epigenetic changes in neuronal DNA; (b) at the tissue level it may affect intracellular communication (synaptic contacts), number of cells (reduction of neuronal density), composition of the extracellular matrix (accumulation of amyloid plaques), and neuroinflammation; (c) at the systemic levels it may alter the brain's regulation of behavior (cognitive decline).