Sentences with phrase «cellular cytotoxicity»
Trastuzumab directly inhibits the proliferation of HER2 - overexpressing breast cancer cells and induces immune - mediated killing of target cancer cells through antibody - dependent cellular cytotoxicity [20].
http://journals.plos.org/
A failure to repair DNA lesions can result in mutagenesis, large scale genome aberrations and cellular cytotoxicity.
Rituximab is thought to function through activation of natural killer cells, resulting in cellular cytotoxicity.
Antibody dependant cellular cytotoxicity (ADCC)- When antibodies coat an HIV - infected cell identifying it as something abnormal that needs to be killed.
Not exact matches
They can be localized within or on cellular plasma membranes and have low cytotoxicity when interfaced with experimental brain systems.
Though this exploitation of biochemical and cellular pathways, the Gelipo - TRAIL - Dox combo accumulated more than the controls in the affected tumor tissue and had a greater cytotoxicity.
The bioconjugate and unmodified QD treatments (the control) were tested for cellular uptake and cytotoxicity in MCF7 (cancerous) and MCF - 10A (comparison) cell cultures.