Sentences with phrase «cellular damage in»

-- Deficiency of vitamin C and E. Both vitamins are antioxidants which help to repair cellular damage in the body including blood vessels;

Both vitamins are antioxidants which help to repair cellular damage in the body including veins.

Researchers have suggested that both zinc and antioxidants delay the progression of age - related macular degeneration (AMD) and vision loss, possibly by preventing cellular damage in the retina [71,72].

It is thought that these agents may help to prevent the accumulation of intracellular sorbitol that leads to cellular damage in diabetics.

* This important antioxidant neutralizes free - radicals which cause cellular damage in the body and contribute to the aging process.

The symposium on Cellular responses to cellular damage in Schizosaccharomyces pombe will take place on 1 - 4 October 2007.

Not exact matches

Purple cauliflower garners its hue from the antioxidant anthocyanin, which is also found in blueberries and red cabbage and helps to fight cellular damage.

Other essential nutrients in onions are antioxidants that promote cellular structuring, increase immunity, and protect from free radical damage to the cells.

Carcinogens may cause cancer by altering cellular metabolism or damaging DNA directly in cells, which interferes with normal biological processes.

In schizophrenia, excessive oxidation — which involves the same type of chemical reaction that causes metal to corrode into rust — is widely thought to cause inflammation and cellular damage.

The researchers found that the immune cells in the skin of this animal model generated large amounts of the cytokine IL - 17 — a protein of the immune system that activates cellular inflammation in response to damage.

Now 24, he is a first - year graduate student in the department of cellular and structural biology at the University of Texas Health Science Center in San Antonio (UTHSCSA), where he is studying the role of oxidative damage — the wear and tear inflicted upon the cell by toxic molecules called free radicals — in the aging process.

The p53 protein helps keep cancer in check by ordering a cellular mop - up in response to DNA damage.

Research has led to discoveries in the use of antioxidant therapy as a proactive measure to counteract the production of free radicals and thus stave off the potential for prolonged cellular damage.

«Transplanted hematopoietic stem cells reverse damage caused by neuro - muscular disorder: In mouse model of Friedreich's ataxia, a single infusion measurably restored normal cellular functions.»

A common feature of neurodegenerative diseases such as Alzheimer's, Parkinson's or Huntington's disease are deposits of aggregated proteins in the patient's cells that cause damage to cellular functions.

But researchers have developed an imaging technique that shows, in real time, what happens when things start going awry — a tool that could help doctors diagnose mitochondrial injuries before they have the chance to do serious cellular damage.

In this case, he was testing the idea that a buildup of cellular damage caused by oxidation — technically, the chemical removal of electrons from a molecule by highly reactive compounds, such as free radicals — is the main mechanism behind aging.

Intermittent dosing with rapamycin selectively breaks the cascade of inflammatory events that follow cellular senescence, a phenomena in which cells cease to divide in response to DNA damaging agents, including many chemotherapies.

Obesity suppresses an important cellular process that prevents kidney cell damage, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

«First aid kit in some living organisms helps fix DNA after lengthy sun exposure: New study unveils the binding mechanisms of enzymes capable of repairing DNA damaged by UV light before any risk of cellular malfunction sets in.»

This metabolic demand makes brain cells particularly vulnerable to damage from oxidative stress, in which reactive oxygen species (ROS), sometimes called free radicals, exert toxic effects on cellular components.

The rate of this cellular damage can vary from person to person, and may be dictated by genetics, lifestyle and the environment we live in.

They found that by attaching to a mitochondrial protein called TOM20, alpha - synuclein prevented the mitochondria from functioning optimally, which resulted in the production of less energy and more damaging cellular waste.

The analysis also showed that the preponderance of host responses shifted rapidly from activation of genes involved in cell damage and inflammation toward those linked to promotion of cellular and organ repair.

Interest in studying tRNA fragments has been increasing swiftly as studies have shown that the fragments have regulatory roles and implicated individual fragments in cellular processes such as translation initiation, response to viral infection, response to DNA damage, etc..

As described in the article, when NANOG was increased in these mice, the epithelia showed an increase in cellular proliferation, hyperplasia, and an increase in the amount of DNA damage in the cells.

Like jewels in a vault, our precious genetic material is stored in the nucleus of a cell — sequestered away from potentially damaging cellular components and toxins so that no harm can come to it.

In 2011, UT Southwestern researchers in Dr. Levine's laboratory identified the protein Smurf1 as important for the elimination of viruses and damaged mitochondria from cells via a cellular housekeeping process called autophagIn 2011, UT Southwestern researchers in Dr. Levine's laboratory identified the protein Smurf1 as important for the elimination of viruses and damaged mitochondria from cells via a cellular housekeeping process called autophagin Dr. Levine's laboratory identified the protein Smurf1 as important for the elimination of viruses and damaged mitochondria from cells via a cellular housekeeping process called autophagy.

Scientists do not yet fully understand how antibiotics work on the molecular level, but they think that the drugs are effective in part by introducing reactive oxygen to bacterial cells, which damages key cellular structures.

This uncontrolled inflammation is associated with changes in bacteria populations in the gut, which can invade the mucosal tissue after damage to the protective cellular barrier lining the tissue.

But until he understands how the cells are stressed in the first place, he won't know much: «We frankly don't have a clue as to how much microwave radiation is needed to cause irreversible damage to cellular proteins.

Her research team found that cellular oxidative stress (arising because of reactive oxygen species) increases in mice exposed to THS, damaging proteins, fats and DNA, and leading to hyperglycemia (excess glucose in the blood stream) and insulinemia (excess insulin in the blood)-- a condition also called insulin resistance.

Now, Professor Martin and colleagues have discovered that in response to specific types of cell damage, Parkin can trigger the self - destruction of «injured» nerve cells by switching on a controlled process of «cellular suicide» called apoptosis.

But in obesity, accumulation of lipids can cause fatty liver, resulting in cellular damage to the organ.

However, excessive generation of ROS and / or a fall in antioxidant defences can lead to indiscriminate damage, resulting in cellular oxidative stress [27].

DNA damaging agents can promote ageing, disease and cancer and are widespread in the environment as well as being produced within human cells as normal cellular metabolites

This is as you'd predict, based on the principle of the «weakest link in the chain»: to move the needle on maximum lifespan, you have to push back on all of the cellular and molecular damage of aging, not just one form.

Imaging mismatch repair and cellular responses to DNA damage in Bacillus subtilis.

Based on the previous evidences, it rusults important to maintain cellular NAD + availability especially in mitochondria when stresses induce a major consumption of NAD + and ATP and prone the organism more susceptible to ROS damages.

Researchers have uncovered that CT scans can cause cellular damage, saying that it will be in a patient's best interest if their doctor explored dose reduction strategies.

O'Shea says this may explain why people with conditions resulting in high levels of cellular DNA damage (e.g., cancer, chemotherapy, inflammation and aging) are more susceptible to viral infections.

We hypothesize that upon retinal neuronal damage MG or RPE cells undergo defined and controlled changes in cellular and molecular phenotype towards a cell with progenitor properties — this process that we are studying we call regenerative reprogramming.

The consensus position in the research community is that tracing back the biochemical chains of cause and effect to root causes, something that is not yet possible for many common medical conditions, will show that all age - related conditions and their complexities are the consequences of a comparatively small number of types of cellular and molecular damage.

We are developing a new kind of medicine: regenerative therapies that remove, repair, replace, or render harmless the cellular and molecular damage that has accumulated in our tissues with time.

Molecular and cellular profiles of the resolution phase in a damage - associated molecular pattern (DAMP)- mediated peritonitis model and revelation of leukocyte persistence in peritoneal tissues.

In 1963, Hruban and colleagues showed that damaged structures within a cell were sequestered and degraded, and that this was a normal and beneficial response to cellular injuries such as starvation or oxygen deprivation.

Meanwhile, the same thing goes wrong in the aging brain, bringing one more insult to the accumulating cellular and molecular damage that slowly erodes the functional capacity of the aging brain, culminating in Parkinson's and other degenerative syndromes.

Ionizing radiation is a potent DNA damaging agent that interacts with cellular DNA and induces lesions in the irradiated cells and prevents cell proliferation and induces cell death by apoptosis or necrosis depending on the radiation dose.

The damage that it will repair is the one that is causal in senenscence of DNA pathway (such x-ray radiation causing senescence) and oncogenic activated senescence; but not of the type of replicative senescence (that's the domain of telomeres / telomerase / sub-telomeres and epigenetics) and cellular replication / proliferation.