Not exact matches
In schizophrenia, excessive oxidation — which involves the same type of chemical reaction that
causes metal to corrode into rust —
is widely thought to
cause inflammation and
cellular damage.
A common feature of neurodegenerative diseases such as Alzheimer's, Parkinson's or Huntington's disease
are deposits of aggregated proteins in the patient's cells that
cause damage to
cellular functions.
In this case, he
was testing the idea that a buildup of
cellular damage caused by oxidation — technically, the chemical removal of electrons from a molecule by highly reactive compounds, such as free radicals —
is the main mechanism behind aging.
«Lots of things bind to heparan sulfate to trigger various
cellular responses, but when active heparanase levels
are high, the receptors become degraded, so bound molecules
are released and can
cause damage to the local tissues,» said Agelidis.
But until he understands how the cells
are stressed in the first place, he won't know much: «We frankly don't have a clue as to how much microwave radiation
is needed to
cause irreversible
damage to
cellular proteins.
What happens over time
is that those free radicals, they can accumulate and then
cause cellular damage.
«TDP43
is a «Goldilocks» protein: too much, or too little, can
cause cellular damage,» says first author Sami Barmada, MD, PhD, an assistant professor of neurology at the University of Michigan Medical School and former post-doctoral fellow at Gladstone.
P16: P16
is perhaps best known as an indicator of
cellular senescence, a part of the mechanisms that
cause damaged cells or those at the Hayflick limit to become senescent or self - destruct.
Researchers have uncovered that CT scans can
cause cellular damage, saying that it will
be in a patient's best interest if their doctor explored dose reduction strategies.
New research by scientists shows that when
cellular barriers
are exposed to metal nanoparticles,
cellular messengers
are released that may
cause damage to the DNA of developing brain cells.
The consensus position in the research community
is that tracing back the biochemical chains of
cause and effect to root
causes, something that
is not yet possible for many common medical conditions, will show that all age - related conditions and their complexities
are the consequences of a comparatively small number of types of
cellular and molecular
damage.
Regulatory reform will
be necessary to adopt a system based on treating existing pathology to one based on repair of the
cellular and molecular
damage that
causes it, with the outcome
being the delay and eventual indefinite postponement of the very onset of such pathology with age.
The
damage that it will repair
is the one that
is causal in senenscence of DNA pathway (such x-ray radiation
causing senescence) and oncogenic activated senescence; but not of the type of replicative senescence (that
's the domain of telomeres / telomerase / sub-telomeres and epigenetics) and
cellular replication / proliferation.
Despite the protection offered by the
cellular environment, the integrity of DNA
is continuously challenged by a variety of endogenous and exogenous agents (e.g. ultraviolet light, cigarette smoke, environmental pollution, oxidative
damage, etc...) that
cause DNA lesions, interfering with proper
cellular functions, such as transcription, inducing premature
cellular death and finally premature ageing and organs dysfunctions.
Peroxynitrates results in lipid peroxidation of membranes and
cause disturbances in tissue homeostasis that
is severe enough to
cause cellular damage and eventually cell death (Beattie et al., 2000).
Brussels sprouts (and other members of the cabbage family) promote the production of glutathione, a great antioxidant to help minimize
cellular damage caused by free radicals that
are formed from exposure to infectious organisms.
He Shou Wu stimulates the production of Superoxide Dismutase (SOD), the most powerful antioxidant in the human body, which works to protect to
cellular DNA from oxidative
damage, which
is widely believed to
be one of the primary
causes of aging.
Free radical
damage caused by electron - seeking, highly reactive, oxidative molecules has
been identified as the source of many maladies through mechanisms such as inhibition of telomerase, changes to
cellular permeability and DNA
damage.
According to the theory, the resulting
cellular damage is what essentially
causes aging.
Previous research has also shown that short - term fasting can produce molecules called free radicals, which
are highly reactive chemicals that can
cause damage to the body at a
cellular and may
be associated with impaired organ function, cancer risk and accelerated aging.
DNA
damage is repairable, but PARPS consume up to 80 % of available NAD + in older humans, meaning it
is a major
cause of NAD + shortage, leaving less NAD + for
cellular respiration, fighting inflammation, and disease (21)
They
are highly reactive radicals that can start a chain reaction in the body, such as
damaging cellular components, like DNA or the cell membrane,
causing cells to function poorly or die.
Electrolytes (a fancy name for micronutrients)
are depleted rapidly, while antioxidants (such as vitamins A, C, E, CoQ10 and alpha lipoic acid)
are utilized more quickly, in order to reduce the
cellular oxidative
damage caused by exercise.
Papaya
is also an excellent source of antioxidants, such as beta carotene, a precursor of vitamin A (retinol) and vitamin C (ascorbic acid) that prevents the
cellular damage caused by free radicals and promote cardiovascular health.
Furthermore, it
is known that older follicles have fewer defenses against
cellular damage caused by oxidative stress, and that this
is related to poorer IVF outcomes.
Antioxidants
are touted for their ability to help the body eliminate free radicals, which over time
cause cellular damage that can lead to a variety of health problems.
Normal blood sugar levels have
been continually revised downward over the past several decades as it
's determined that current levels
cause cellular damage.
Antioxidants fight
cellular damage caused by free radicals, which
are waste products of metabolism.
Oil extracted from pumpkin seeds contains about 50 % vitamin E, which shields the skin from
damage caused by free radicals and
is used for the necessary
cellular communication the skin needs to heal itself.
A review published in «Antioxidants Sport Nutrition» in 2015 also notes that green tea's antioxidant activity may
be especially beneficial for preventing
cellular damage caused by exercise, since your body burns more calories and creates more free radicals during exercise.
Additionally, scots pine's antioxidant action have
been shown some influence in preventing
cellular damage caused by free radicals, which have
been linked to many age - related, degenerative diseases.
One of the main
causes of inflammation
is an excess amount of free radicals within the body, which
causes cellular damage.
Oxidative
damage can
be caused by several factors, especially by those factors on the
cellular level.
When we
are exposed to pollutants and toxins, free radicals
cause cellular damage, which in turn contributes to inflammation that can exacerbate conditions like allergies and asthma.
Free radicals
are able to deform other biological molecules,
causing the
damage to the
cellular structure and ultimately obstructing
cellular function.
Vet Classics Antioxidants with Coenzyme Q - 10
is a unique blend of highly concentrated antioxidants to help eliminate free radicals that can
cause cellular damage.
It
damages cellular DNA and worse, it can
cause death by activating latent viral infections (thought to
be carried by nearly all phytoplankton).
The
cellular damage caused by the organism brings about inflammation, which
is thought to increase the host's risk for HIV infection.