The destruction of red blood cells often leaves recognizable
cellular debris in the blood stream.
The higher scores (> 3) in some groups related primarily to the fact that virus infection had induced inflammatory infiltrates and epithelial cell necrosis with desquamation of the epithelium and collection of
cellular debris in airways of these animals.
Perivascular and peribronchial inflammatory infiltrates were observed in most fields along with desquamation of the bronchial epithelium, collections of edema fluid, sloughed epithelial cells, inflammatory cells and
cellular debris in the bronchial lumen.
Not exact matches
At first it was thought that only functioned as
cellular debris warehouses but
in recent years has been that could have an important role as a messenger between cells of the body and now many groups focus their research on the role that could be played exosomes
in various diseases, including cancer.
«
In the best - case scenario, we thought we could hopefully prevent the loss of vision in these patients,» he says, because RPE cells are known to help maintain existing photoreceptors, in part by digesting the cellular debris that they she
In the best - case scenario, we thought we could hopefully prevent the loss of vision
in these patients,» he says, because RPE cells are known to help maintain existing photoreceptors, in part by digesting the cellular debris that they she
in these patients,» he says, because RPE cells are known to help maintain existing photoreceptors,
in part by digesting the cellular debris that they she
in part by digesting the
cellular debris that they shed.
This enabled the researchers to detect mutations
in three genes — GNPTAB, GNPTG, and NAGPA — involved
in the function of lysosomes, the
cellular sacs where
debris gets recycled.
This discovery lends more weight to the growing evidence that inflammation — and our immune system's hyperactive reaction
in mopping up the
cellular debris left by the wayward plaques and tangles — plays a key role
in the spread of the disease.
This mechanism helps «clean up»
cellular debris at the synapse, by engulfing the
debris in a membrane and then removing it, for instance.
This discovery therefore represents an important advance
in the search for treatments for neurodegenerative diseases, such as Alzheimer's — which are caused by clumped together
cellular debris.»
In macular degeneration, clumps of yellowish
cellular debris — possibly of retinal origin — gradually accumulate within and beneath the retinal pigment epithelium.
Building on these extreme examples that emphasize the potential roles played by healthy lysosomes
in protecting neurons against the age - dependent accumulation of toxic
cellular debris, we ultimately seek to understand how neurons sense and regulate the status of their lysosomes, how lysosomes are affected during age - related disease states and whether lysosomal function can be modulated for therapeutic purposes.
They hold neurons
in place, nourish them, digest
cellular debris, and are suspected to be the origin of glioblastoma.
Scoring - 0 - no definite pathology, 1 - mild peribronchiole and perivascular
cellular infiltration, 2 - moderate peribronchiole and perivascular
cellular infiltration, 3 - severe peribronchiolar and perivascular
cellular infiltration with thickening of alveolar walls, alveolar infiltration and bronchiole epithelial cell necrosis and
debris in the lumen.
In the vaccine comparison experiment, lung lesion scores for histopathology were graded for individual animals on a scale of 0 to 4 where 0 — 2 represented degree of
cellular infiltration and 3 — 4 represented the degree of bronchiolar epithelial cell necrosis and airway
cellular debris (figure 2A).
Scoring 0 - no definite pathology, 1 - mild peribronchiole and perivascular
cellular infiltration, 2 - moderate peribronchiole and perivascular
cellular infiltration, 3 - severe peribronchiole and perivascular
cellular infiltration with thickening of alveolar walls, alveolar infiltration and bronchiole epithelial cell necrosis and
debris in the lumen.
These effects appear to be linked to progranulin's involvement
in phagocytosis, a type of
cellular house - keeping whereby cells «eat» other dead cells,
debris, and large molecules.
Long considered uninteresting
cellular debris, it is now appreciated that extracellular vesicles (EVs) can play a major role
in intercellular signaling.
Stimulation of gamma waves reduced levels of amyloid - β, decreased phosphorylation of tau, and led the brain's immune cells — microglia — to perform their usual housekeeping role, clearing away
cellular debris, including amyloid - β (as opposed mounting an inflammatory response as microglia do
in Alzheimer's disease, Tanzi explained).
Rats fed protein - deficient diets have decreased DBP concentrations and a decreased ability to regulate calcium metabolism.38 Humans with acute liver failure also have depressed levels of DBP.39 This may be because the synthesis of DBP
in the liver declines during such a condition, but DBP also plays a secondary role
in scavenging harmful
cellular debris from the blood; therefore, any kind of acute tissue damage can overwhelm our supply of DBP.
«Stem cells are involved
in tissue regeneration, where there is a high rate of tissue regeneration, there is always heightened turnover of
cellular debris — similar to that seen
in autophagy, and with ramped up
cellular toxin disposal... This is big.»
The serum aims to promote the natural purification process of removing
cellular debris accumulated
in the skin throughout the day, a process which is known to accelerate aging.
An abscess, which is a collection of
cellular debris (pus) surrounded by an inflamed area, can form anywhere on or
in the body.