Sentences with phrase «cellular differentiation»
Cellular differentiation refers to the process in which cells in a developing organism or tissue change and specialize in their structure and function. In simpler terms, it means that cells start to become different from each other to perform specific tasks and contribute to the overall functioning of the organism or tissue. Full definition
The central problem in pattern formation is how can genetic information be translated in a reliable manner to give specific spatial patterns of cellular differentiation.
sciencedaily.com
The research centre currently consists of seven groups studying epigenetic mechanisms regulating cellular differentiation programs.
Such marks key roles in the process of cellular differentiation, allowing cells to maintain different characteristics despite containing the same genomic material.
Shorter patient survival was generally associated with up - regulation of genes involved in mitosis and cell growth, and down - regulation of genes involved in cellular differentiation.
In studies of cancer cells and of tumors in mice, vitamin D has been found to have several activities that might slow or prevent the development of cancer, including promoting cellular differentiation, decreasing cancer cell growth, stimulating cell death (apoptosis), and reducing tumor blood vessel formation (angiogenesis)(3 - 6).
One likely reason for this is that animals undergo cellular differentiation; human life begins as a single cell that differentiates into the various cell types needed for different organs, body parts, blood, the immune system, etc..
Yamanaka's group and two others followed up earlier this year with firmer evidence that these induced pluripotent stem (iPS) cells faithfully mimicked the patterns of gene activity and cellular differentiation observed in embryonic stem cells.
Special focus is placed on Rho - kinase inhibition, relating to its potential to promote and support extracellular matrix production in cultured chondrocytes and its role in fibroblast cells as a part of direct chemical cellular differentiation.
Wang, T.C., GOLDENRING, J.R., Dangler, C., Millar, A., Jeon, W.K., Ito, S., Koh, T.J. and Fox, J.G. C57BL / 6 mice deficient in secretory phospholipase A2 show increased apoptosis and altered cellular differentiation during Helicobacter felis infection.
In eukaryotes, a homeobox encodes a protein domain (the homeodomain) which can bind DNA that act as part of transcription factors to switch on cascades of other genes that induce cellular differentiation by initiating the cascades of coregulated genes required to make individual tissues, organs, or body parts.
Gene regulation gives the cell control over its structure and function, and is the basis for cellular differentiation, spatial distribution, and the versatility and adaptability of any organism.
Most, if not all, cancerous states reflect inappropriate or incomplete cellular differentiation.
The preformed vitamin A in Eye and Body Complete is retinyl palmitate, which provides adequate vitamin A for night vision, wound healing, immune protection and appropriate cellular differentiation.
The key is to not suppress your immune system with PUFA and maintain sufficient vitamin d levels such that you have proper cellular differentiation and don't get cancer in the first place because your immune system knows how to fight it.
The research has also investigated the role of Rho - kinase inhibition on cellular - scale protein expression and stimulation of cellular differentiation of fibroblast cells.
It is involved in cellular differentiation and slows the aging process
It is also a cancer fighting agent as it promotes cellular differentiation (differentiated cells are needed to perform specialized functions effectively), and slows down the rate at which cells multiply.
Vitamin A plays important roles in vision, cellular differentiation, growth, reproduction and immune - competence.
The authors explain in the article that NSD1 mutation has recently been linked in the scientific literature to the blocking of cellular differentiation and the promotion of oncogenesis in this type of tumor.
This cellular differentiation takes place exactly as Alan Turing predicted it would in his 1952 paper, «The Chemical Basis of Morphogenesis.»
«Cancer stem cells are capable of self - renewal, cellular differentiation and maintain their stem cell - like characteristics even after invasion and metastasis.»
The combining of the VEGF and GDNF not only significantly reduced the degeneration of the dopaminergic neurons of the black substance, it also induced the formation of new cells and cellular differentiation.
The new paper is «by far the most complete survey of a cellular differentiation event,» says Juha Kere, a molecular geneticist at the Karolinska Institute in Stockholm, who is not affiliated with the FANTOM group.
A growing number of evidence suggests that they play central roles on cancer development and cellular differentiation.
Dr. Nagy is a physician by training and a molecular and cell biologist with a long - standing research interest in the biology of gene - expression regulation, cellular differentiation, and their contribution to human diseases.
The CCP is engaged in numerous multidisciplinary projects in other model systems (e.g. fly, zebrafish, yeast) that aim to determine how complex molecular circuits function and evolve in response to genetic and environmental changes, cellular differentiation, evolution and disease.
The current dogma of cellular differentiation presents a model of progressive closing of the regulatory potential of the genome during cellular differentiation.
Research Focus & Career Goals: Recent work, to which I have also contributed, and from some other laboratories has established that global regulation of cellular differentiation is the result of the coordinated interplay of dynamic changes in the organization of chromatin, epigenetic modifications, lncRNAs and transcription factors.
The van Wijk lab is comparing leaf development and cellular differentiation in the C3 species rice to that in the C4 species maize mainly using large scale comparative protein (proteome) analysis.
Comparing leaf development and cellular differentiation in the C3 species rice to that in the C4 species maize mainly using large scale comparative protein (proteome) analysis.
The thyroid gland produces three hormones that affect growth, metabolism, and cellular differentiation.
Vitamin A: Vitamin A aids vision, growth, immune function, fetal development, cellular differentiation, and trans - membrane protein transfer.
Unlike normal plasma cells, the malignant plasma cells look large and round with a high mitotic index (measure of the proliferation of a cell population) in early stages of cellular differentiation.
For dogs, vitamin A is essential for bone growth, reproduction, cellular differentiation and a good immune response.