Sentences with phrase «cellular environment»

Instead of giving it an organic texture and placing it in a traditional cellular environment, I decided to run with the mechanical theme.

The unique cellular environment of nerve cells in the central nervous system may be why regeneration is prevented.

They change the local cellular environment by changing the biochemistry.

In cellular environment, the existing and maturation of the putative miRNA - like fragment in the presence of a cloned pre-miR sequence were then verified.

Until now, scientists did not have a method for studying the mechanical characteristics of native cellular environments — that is, cells surrounded by other cells and matrix scaffolds within living tissues.

This applies even more so if one wants to investigate the structural changes in the natural cellular environment, where countless simultaneous processes make it very hard to isolate any specific information from the general noise.

Using molecular simulations that modeled a potassium channel and its immediate cellular environment, atom for atom, University of Chicago scientists have revealed this new mechanism in the function of a nearly universal biological structure, with implications ranging from fundamental biology to the design of pharmaceuticals.

Creatine acts by supporting the reproduction of ATP (fancy term for energy) in muscle tissue resulting in cell volumization which can create a more optimistic cellular environment for muscle growth.

How cells in the embryo coordinate epithelial plasticity with cell fate decision in a fast changing cellular environment is largely unknown.

With regard to autism spectrum disorders, one has to consider the entire cellular environment, or niche.»

They also plan to evolve the chemistry behind the materials so that it may be possible for gels to better mimic more complex cellular environments beyond the control of stiffness alone, as well as investigate how dynamic changes in matrix properties — a hallmark of the stem cell niche — can be mimicked in the laboratory.

«This opens the door to an entirely different aspect of [the] cellular environment that we had not previously considered in eye development.»

Costantini, Lindsey M., et al. «A palette of fluorescent proteins optimized for diverse cellular environments.»

Recently developed superresolution microscopy techniques however are ideal tools that allow us to study these assemblies in their natural cellular environment and to understand their modus operandi.

As diamond conducts heat well, the nanocrystal is likely to be the same temperature as its immediate cellular environment.

A second line of research is to use skeletal muscle formation in the chick embryo as a model to understand how cells within tissues display complex behaviours while being exposed to an ever - changing cellular environment.

Thus, some, but probably not all, of the differentiated properties of these cells are a consequence of their cellular environment.

How do the genetically diverse cells in a tumour interact, for example, and what is the role of the cellular environment that they inhabit?

Using a tool that mimics the cellular environment, Princeton University researchers reconstituted a key receptor protein responsible for regulating S. aureus virulence.

To maintain normal cell physiology, a temperature control system maintains the cellular environment at 37 °C (or another preset temperature).

It also shows a preference for binding with dsRNA over dsDNA, which is an important selective process for future applications in a cellular environment where RNA and DNA co-exist.

The researchers discovered that the amount of nutrients in the cellular environment is a major factor influencing this process.

«Following on the work of TSRI Professor Ardem Patapoutian, who has identified many of the genes that endow these neurons with selective responses to temperature, pain and pressure, we have found a way to produce induced sensory neurons from humans where these genes can be expressed in their «normal» cellular environment,» said Associate Professor Kristin K. Baldwin, an investigator in TSRI's Dorris Neuroscience Center.

While glycans are usually attached to the proteins making up antibodies while they are being assembled within cells, recent evidence suggests they could be modified outside of the cellular environment.

Many scientists had assumed, however, that the cellular environment in living tissues would interfere with the reprogramming process, especially because natural development is usually a one - way street, from stem cells to differentiated and mature tissue cells.

Finally, the researchers discovered that ROS generation subsided as the iPSCs matured, and these mature stem cell colonies survive best in a cellular environment with low levels of ROS.

Through a variety of mechanistic interactions, mTORC1 interprets cues in the cellular environment, including the availability of nutrients, and signals the organism to act accordingly.

Through a series of protein - mediated signals, mTORC1 interprets cues in the cellular environment, including nutrient availability, and instructs the organism to react accordingly.

MiRNAs control critical processes in mammalian cells to re-shape the parasite's cellular environment and therefore constitute potential molecular therapeutic targets.

The researchers speculate that the non-neuronal cells play a vital role in nourishing the motor neurons and in scavenging toxins from the cellular environment.

Despite the protection offered by the cellular environment, the integrity of DNA is continuously challenged by a variety of endogenous and exogenous agents (e.g. ultraviolet light, cigarette smoke, environmental pollution, oxidative damage, etc...) that cause DNA lesions, interfering with proper cellular functions, such as transcription, inducing premature cellular death and finally premature ageing and organs dysfunctions.

To explore this question, they generated neural cells from embryonic stem cells and then removed DNMT3A from the cellular environment.

Stress granules are one mechanism cells use to halt production until the cellular environment normalizes, which is when stress granules typically dissolve.

Our goal is to identify signaling pathways which control or coordinate these different phenotypic transitions and to evaluate how these pathways can be influenced by the cellular environment, altered in pathological contexts or serve as therapeutic targets.

One strategy to encourage nerve fiber growth is to remove inhibitory factors in the cellular environment.

Another major interest of the laboratory lies in exploring how changes in the microenvironment, or the cellular environment in which the tumor exists, including immune cells, fibroblasts, blood vessels, and signaling molecules, contribute to both tumor progression and therapy resistance.

Marine Collagen, especially fish collagen, is the major component of the extracellular matrix and is useful for mechanical protection of tissues, organism and physiological regulation of a cellular environment.

Redox Select ™ provides a wide range of antioxidant ingredients that are both water soluble and fat soluble, enabling the product to be active both inside and outside the cellular environment.

The cellular environment and how it affects gene expression, and ultimately health, is the subject of epigenetics.

Brennan writes: «If you eat well, and not too much, and if you get a good amount of exercise, you can actively promote anticancer conditions in the cellular environment of your body.

Sodium is an essential mineral for cats, maintaining proper muscle and nerve cell function and preventing cells from swelling or dehydrating by maintaining the cellular environment.

Jeremy Couillard views science as an aesthetic in his painting, which illustrates the evolution of totem poles in a cellular environment — in architectural and biological terms.