Muotri's work is a nice demonstration of the power of mini-brains to help understand the early,
cellular features of neurological disorders, says Madeline Lancaster at the MRC Laboratory of Molecular Biology in Cambridge, UK, who developed the organoid - growing method Muotri used.
Not exact matches
Finally, the most absurd
feature of your scenario is the idea that any extraterrestrial creature would just happen to have, first, DNA as it's basic molecule
of biological information storage, second,
cellular machinery anywhere remotely similar to what animals on Earth have, and finally, would just happen to be close enough genetically to be able to mix their DNA with the DNA
of any terrestrial being, and come out with a viable result.
A common
feature of neurodegenerative diseases such as Alzheimer's, Parkinson's or Huntington's disease are deposits
of aggregated proteins in the patient's cells that cause damage to
cellular functions.
Just as a careful watcher can gauge the emotional state
of a person by noticing a blush or other visual cues, scientists are becoming adept at discerning the state
of a cell with the help
of molecular «paints» that highlight more than a thousand
cellular features together.
When this model was in its softest mode, normal (benign) mammary epithelial cells behaved normally within it, forming
cellular structures referred to as acini that capture many key
features of the normal in vivo mammary epithelium.
A unique
feature of this DREADD system not found in other methods is that it is not limited to the control
of neurons — activity levels
of certain enzymes in almost every tissue type can be controlled to probe mechanisms
of basic
cellular function.
A unique
feature of this new resource is that it links various
cellular processes in a molecular network and provides a more holistic view
of the disease.
The aim
of the team was to gain insights in to the molecular
features of totipotency and to work out how changes in
cellular plasticity may occur.
It's now possible to not only model disease using the cells, but also to compare iPSCs from humans to those
of our closest living relatives --- great apes, with which we share a majority
of genes --- for insight into what molecular and
cellular features make us human.
This new bone cancer model does a better job than previously used mouse or
cellular models
of «recapitulating» the
features of bone cancer cells driven by key genetic changes.
Molecular, subcellular and
cellular studies in whole animals or humans; and novel molecular, immunological or biophysical studies
of hormone action are also
featured.
In order to dissect these defects, we utilize a unique approach including deep assessment
of patient phenotype, clinical genetic testing to identify underlying genetic contributions to these
features, and the application
of combinatorial functional omics (transcriptome, metabolome, etc.) to uncover the pathological
cellular states that result from these genetic changes.
Here we report the generation
of additional mutant Xpd alleles that fail to support viability on their own but nevertheless ameliorate TTD - associated premature segmental ageing, cutaneous
features,
cellular DNA repair capacity, and UV survival when present in a compound heterozygote state.
Cryo - fluorescence microscopy is exploited to navigate the
cellular landscapes for
features of interest before zooming in on these areas by cryo - electron tomography.
Polarization, which confers asymmetry at molecular,
cellular and tissue scales, is a fundamental process establishing key
features of biological systems.
One new way that scientists study this process
of cellular development — and a way in which they hope to grow replacement tissue for medical treatments in the future — is by recreating the essential
features of human brains, eyes, lungs, and guts in a petri dish.
«Noise can be both an obstacle for some types
of cellular behaviors as well as a useful
feature for others,» Elowitz said.
A crisp image can tip the evidentiary scale toward one
of several competing theories about the identity
of a
cellular or tissue
feature, how it is structured...
In the study, members
of the Gottesfeld lab, led by first author Sherman Ku, a graduate student in the Scripps Research Kellogg School
of Science and Technology, created a
cellular model that did reproduce this
feature.
«We haven't had human
cellular models that faithfully reproduce this
feature of the disease,» said Gottesfeld.
Important
features of XMRV biology include (1) tropism for a variety
of cell lines, including prostate cancer DU145 and LNCaP cells [27], [43], [48], and human neural cell types [57], (2) adaptations that promote growth in prostate epithelium and human - derived prostate cancer cell lines including an androgen response element in the promoter region [58] and downregulation
of APOBEC3G [59], and (3)
cellular effects with potential oncogenic properties including increased tumor aggressiveness mediated by downregulation
of p27 [60] and differential regulation
of several microRNAs [61].
We also employ this technology to probe the functionality
of an entire MRE network under
cellular homeostasis, and show that high - resolution analysis
of the GenERA dataset can be used to extract functional
features of MREs.
Hi George, Seems like i belong to the first type «One type
featured high rates
of cholesterol (re) absorption with low rates
of cellular cholesterol synthesis.
One type
featured high rates
of cholesterol (re) absorption with low rates
of cellular cholesterol synthesis.
Numerous
features of cellular metabolism rely on zinc.
Together they talk about what the benefits
of airless pump technology are for both the product, and the consumer —
featuring the STEM
CELLULAR ™ Anti-Wrinkle Booster Serum, which is packaged using this technology.
Life Extension Liver Efficiency Formula
features two state -
of - the - art molecular energizers shown to promote healthy liver function at the
cellular level; Schisandra chinensis which supports glutathione and...
Life Extension Liver Efficiency Formula
features two state -
of - the - art molecular energizers shown to promote healthy liver function at the
cellular level; Schisandra chinensis which supports glutathione and Extramel, the source
of superoxide dismutase.
These cordless shades
feature a room darkening thermal backing and
cellular fabric that provide two layers
of additional energy - saving insulation to help you save on energy costs.
ABS,4 - Wheel Disc Brakes,5 - Speed A / T, 8 Cylinder Engine, A / C, A / T, Active Suspension, Adjustable Steering Wheel, Air Suspension, Security System, All Wheel Drive, Aluminum Wheels, AM / FM Stereo, Transmission w / Dual Shift Mode, Automatic Headlights, Brake Assist, Bucket Seats, CD Player, Climate Control, Cruise Control, Daytime Running Lights, Driver Air Bag, Driver Illuminated Vanity Mirror, Driver Adjustable Lumbar, Driver Vanity Mirror,Multi - Zone A / C, Auto - Dimming Rearview Mirror, Fog Lamps, Floor Mats, Front Reading Lamps, Gasoline Fuel, Heated Front Seat (s), Heated Mirrors, HID headlights, Intermittent Wipers, Keyless Entry, Leather Seats, Leather Steering Wheel, Mirror Memory, Navigation System, Telematics, Passenger Air Bag, Passenger Illuminated Visor Mirror, Passenger Adjustable Lumbar, Passenger Vanity Mirror, Power Door Locks, Power Mirror (s), Power Driver Seat, Power Folding Mirrors, Power Passenger Seat, Power Steering, Sun / Moonroof, Power Windows, Premium Sound System, Rain Sensing Wipers, Rear Side Air Bag, Rear Defrost, Rear Head Air Bag, Rear Reading Lamps, Seat Memory, Front Side Air Bag, Front Head Air Bag, Steering Wheel Audio Controls, Sun / Moon Roof, Tires - Front Performance, Tires - Rear Performance, Traction Control, Trip Computer, Universal Garage Door Opener, Variable Speed Intermittent Wipers, Engine Immobilizer, Woodgrain Interior Trim, Door / trunk closing assist
feature, Driver programmable daytime running headlamps,Driver - selectable auto on Bi-Xenon high intensity discharge headlamps w / auto level control, heated washers, Halogen front fog lamps, Infared reflective glass, Pwr folding heated memory side mirrors w / auto - dimming left - side mirror, park assist right - side mirror, Pwr tilt / sliding tinted glass sunroof w / one - touch express open / close & memory,Rain - sensing wipers w / heated washer system, heated wiper parking position, Single red rear fog lamp, (4) illuminated vanity mirrors,14 - way pwr heated adjustable memory front bucket seats w / pneumatically adjustable lumbar support, AM / FM / weatherband stereo w / CD, CD changer controls,Anti - theft alarm system w / tow - away protection, remote panic
feature, auto notification via Tele Aid,Auto - dimming memory rearview mirror, Bose sound system - inc: (10) speakers, Bose Audio Pilot digital processing, Carpeted floor mats, Cruise control, Dual zone auto climate control - inc: vents in rear
of console, individual left / right temp controls, rest mode, charcoal filter, humidity sensor, Front center armrest w / illuminated climate - controlled storage, retractable cupholders, Front seatback magazine pockets,Gauges - inc: electro - luminescent analog speedometer, tachometer, fuel & coolant, GPS / CD - ROM based navigation system, Hand polished burl walnut wood trim - inc: dash, console, doors, shift gate, HomeLink compatible 3 - button garage door control, Leather trimmed shift knob,Lighting - inc: front Xenon reading lamps, rear reading lamps, courtesy lamps w / programmable fade - out time, Multifunction display in speedometer face - inc: odometer, trip meter / computer, flexible service system, oil level, digital speed readout, radio / CD / phone status, Multifunction steering wheel - inc: audio, phone, climate & multifunction display controls, Nappa leather seating surfaces, Premium leather upholstery - inc: head restraints, center armrests, door trim inserts, Pwr rear window sunshade w / one - touch express up / down, Pwr tilt / telescopic leather trimmed steering wheel w / easy exit & memory
features, Pwr windows w / one - touch express up / down for all windows, Rear center armrest w / retractable cupholders, Rear window defroster w / auto shutoff, Smartkey system - inc: selectively remote central unlock / locking system, engine disabling security
feature, outside control
of windows / sunroof, Tele Aid GPS system - inc: 24 hr
cellular link to provide emergency aid, information & roadside assistance, automatic collision / alarm notification, stolen vehicle tracking, remote keyless unlocking services, 17 x 7.5 7 - spoke aluminum - alloy wheels,4 - wheel electronic traction system (4 - ETS), 5 - speed automatic transmission w / touch shift & 2nd gear start, 5.0 L SOHC SMPI 24 - valve aluminum - alloy V8 engine, Airmatic air suspension w / adaptive damping system, All wheel drive,Anti - lock braking system (ABS), Brake assist system (applies full braking pwr automatically when needed), Cross-drilled vented front / rear disc brakes w / front Brembo 4 - piston calipers, rear 2 - piston calipers, Electronic brake force distribution, Independent 4 - link front suspension w / anti-dive geometry, Independent 5 - link rear suspension w / anti-dive geometry, P225 / 55HR17 all - season performance SBR tires,Speed - sensitive pwr rack & pinion steering,3 - point seat belts for all seating positions,Anti - lock braking system (ABS), Driver programmable daytime running headlamps, Driver / front passenger front air bag, Head curtain air bag for all outboard seating positions, LATCH universal tethers / anchors for rear outboard seating positions,PRE - SAFE
feature (Helps prepare occupants for a possible collision by tightening front seat belts, adjusts all pwr seats & if a possible rollover occurs, will close sunroof), Side - impact body protection air bag for all outboard seating positions
-- MyGIG ™ provides a cutting - edge multimedia audio and entertainment system, with built - in navigation — UConnect ® Hands - free Communication System provides convenient, voice - activated communication with Bluetooth ®
cellular phones — SIRIUS ® Digital Satellite Radio offers a variety
of commercial - free radio programs and music for enhanced listening enjoyment — Keyless Go allows the driver to start the vehicle with the simple push
of a button — Remote Start starts a secured vehicle with the key fob — More than 25 Safety and Security
Features
This
feature, developed by General Motors and copied by a couple
of other manufacturers such as Mercedes - Benz's TeleAid, uses
cellular technology to notify operators in an emergency, and also can handle less - critical duties.
MITSUBISHI CONNECT is a subscription - based service that
features special technology (like a GPS and a 4G LTE
cellular modem) that can keep track
of your vehicle and help provide assistance when you need it.
Canadian owners
of these vehicles should not be worried because the version
of UConnect sold here does not come with the
cellular connectivity
feature UConnect Access that gave the hackers their opening into the vehicle's computer systems, reports Postmedia.
That it borders on being over the top in electronic complexity was not entirely avoidable given the long list
of features, including a hands - free, built - in
cellular phone with voice activation and quick links to emergency and roadside help; a navigation system; a premium stereo; and dual zone automatic climate control - all
of which have come to be expected in the ultraluxury class.
This generation uses embedded
cellular technology built into the RLX, along with the owner's compatible smartphone and data package, to bring a broad range
of convenience, entertainment and available security
features to the RLX.
Amazon's new 7 - inch Kindle Fire HD will
feature a high - resolution 1,920 x 1,200 - pixel display, a quad - core Qualcomm Snapdragon 800 chipset clocked at more than 2 GHz, 2 GB
of RAM, Wi - Fi, optional
cellular data, Android 4.2.2 Jelly Bean and either 16 GB, 32 GB or 64 GB
of internal storage.
The new iPad mini also now
features multiple - input and multiple - output (MIMO) technology that offers up to 2x faster Wi - Fi, with both 802.11 a / b / g / n Wi - Fi and LTE
cellular models that available with up to 10 hours
of battery life.
For $ 87, the device is less than half the price
of an iPod touch 4G, and
features built - in Autonomous GPS for turn - by - turn navigation, even without a
cellular data connection / service.
The tablet will
feature compatibility with multiple LTE networks in the US, Canada and Europe as well as HSPA + support through the inclusion
of its own Tegra i500
cellular baseband chipset after a year
of development.
According to sources inside Verizon, the company's version
of the tablet will
feature built - in Wi - Fi utilizing Verizon's hotspots for free data; the device will switch onto the 3G
cellular network when it's away from a hotspot.
He also confirmed that Sony is working on adding
cellular networking capability for the download
of new ebooks, one
of the Kindle's popular
features.
It doesn't have a micro USB port or expandable memory (neither
of which iPad has ever
featured), nor does it support 4G
cellular data speeds.
It would have a color screen, most
of the full
features of a laptop, and I can even add
cellular service via tethering to my cellphone or free WiFi.
One
of the original Kindle's breakthrough
features was the ability to download books via
cellular network.
The Wi - Fi version
of the Xoom matches the 32 GB iPad 2 Wi - Fi model in price exactly and will be similar to the 3G Xoom in
features apart from the
cellular link, including the 1 GHz Tegra 2, 1 GB
of RAM, the 1280x800 display, the five - megapixel back camera and the front two - megapixel camera.
Yasuko Matsui: The e-book market in Japan is growing and hit $ 800 million in sales fuelled by the expansion
of the mobile (
cellular or
feature phone) e-book market.
Huawei MediaPad 7 Lite comes preinstalled with Android 4.0 Ice Cream Sandwich OS, sporting a 7 - inch WSVGA touchscreen with 1024 X 600 pixels
of resolution, powered by CortexA8 1.2 GHz processor, 1 GB RAM, 3.2 megapixels rear - facing camera, 0.3 MP front - facing snapper, 8 GB onboard storage, microSD card slot for memory expansion up to 32 GB, 3G
cellular voice support, microUSB 2.0, Bluetooth 3.0, Wi - Fi b / g / n, 3.5 mm headset jack, 4100mAh battery, a whole host
of the Google services and all the regular
features of an Android tablet.
Check out the more details,
features, full specs
of Motorola Xoom, and find out the nearby U.S.
cellular stores using «store locator» link here.
For those that do, finding one that will work with your existing
cellular telephone and offer the
features you want can be tricky, but if you do your homework, you should be able to find a broker that will meet all
of your needs.