Sentences with phrase «cellular function leading»

Topics addressed were techniques and applications of low - light - level therapy, including therapeutic devices and applications, used to stimulate cellular function leading to beneficial clinical effects.

Not exact matches

Leading clinical investigations seeking to address cardiovascular risk reduction beyond lowering LDL - C focus on interrupting the atherosclerotic process (e.g., plaque formation and instability) by beneficially affecting other lipid, lipoprotein and inflammation biomarkers and cellular functions thought to be related to atherosclerosis and cardiovascular events.

Some autopsy data shows that infants of smokers have signs of established hypoxic - ischemic cellular injury in the brain and the heart which probably occurred in antenatal life, may have been caused by suboptimal placental function and may have been sub-clinical, but if the baby continues to be in a vulnerable environment exposed to post-natal passive smoking, this could affect autonomic nervous system function and lead to poor temperature control, and poor heart rate and respiration control.

«Calcium signaling regulates many important cellular functions, like muscle contraction, neural communication, gene transcription and tissue growth,» said Fenfang Li, a postdoctoral research fellow in Zhong's laboratory and lead author of the study.

A «perfect storm» leads to the collapse of almost all the molecular functions of SRY, including cellular trafficking, stability, DNA recognition and gene regulation.»

A team of researchers led by Charles D. Nichols, PhD, Associate Professor of Pharmacology at LSU Health Sciences Center New Orleans, has successfully translated a new technology to better study behaviors and cellular function to fruit flies.

Some of the PCBs are not broken down in this way, and their continued stimulation of AHR2 disrupts cellular functions, leading to toxicity.

«While it is well - established that obesity generates cellular and molecular stress leading to abnormal functioning of many cellular processes, the mechanisms remain incompletely understood,» said senior author Gökhan S. Hotamisligil, chair of the Department of Genetics and Complex Diseases and the Sabri Ülker Center for Nutrient, Genetic, and Metabolic Research.

However, cells with too short telomeres can lose capping function leading to a cellular catastrophe and genetic instability: the origin of many cancer types.

In HRT users, the different myonuclei arrangement optimises cellular level protein transport that leads to improved muscle function.»

These studies will provide new leads to understand the cellular pathways that control K2P function in other organisms.

The work has led him to explore the role of protein phosphorylation in a diverse array of cellular functions, including transformation, cell communication, cell adhesion, cell - cycle regulation, the control of gene expression, and protein degradation.

Importantly, the host cell could have acquired, by the addition of the aerobic function, an increased output of ATP for cellular activities, leading to its improved selective advantage.

Their crisscrossing paths and collective efforts have nonetheless led to a clear - eyed understanding of how neurons — the brain's cellular building blocks — form and function and how ion - conducting channels control the flow of electrical signals through the nervous system.

The new evidence, assembled by a team led by CSHL Associate Professor Lloyd Trotman, contradicts a long - held assumption about PTEN function, and could help scientists design more effective drugs to counteract cancer's hallmark trait, uncontrolled cellular growth.

Overexpression of fluorescently tagged proteins can lead to improper protein localization, protein aggregation, or disruption of normal protein function, and ultimately misinterpretation of the protein's cellular role.

Over the years the mutations and the cells they affect have led us to study new channel proteins, new transcription factors, neurodegeneration, microtubule function and structure, neuronal outgrowth, insulin signaling, cellular ensheathment, and touch sensitivity to give just a partial list.

Now a research team led by Broad Institute Imaging Platform director Anne Carpenter and postdoctoral fellow Mohammad Rohban has shown that a high - throughput, computerized imaging technique for studying morphology, called Cell Painting, can provide insight into the cellular roles of genes or disease - linked gene alleles whose function or impact is unknown.

Glyphosate's ability to inflame cellular membranes and block normal hormone function also promotes the accumulation of fat, leading to unhealthy weight gain and obesity.

First proposed in 1972, the mitochondrial theory of aging suggests that it's free radical damage to our cells» power source, known as mitochondria, that leads to a loss of cellular activity and function over time.

The mitochondrial theory of aging suggests that free radical damage to our cells» power source (mitochondria) leads to a loss of cellular energy and function over time.

«Having enough of a nutrient to prevent one of the deficiency diseases, but not enough to optimize cellular function, will lead to «long - latency» deficiency diseases... For example, if you don't have enough folic acid for optimal function over thirty to forty years, you will double your risk of Alzheimer's disease.»

Aβ is believed to penetrate neuronal plasma membranes, where it leads to lipid peroxidation.10 It has also been implicated in deactivating a subunit of the pyruvate dehydrogenase complex, thereby inhibiting conversion of pyruvate to acetyl CoA and the eventual production of cellular energy as ATP.32 Another way Aβ affects glucose metabolism in the brain is that fragments of Aβ disrupt insulin signaling by binding to neuronal synapses, which alters their shape and function.15, 38 Insulin receptors are abundant at synapses, so if the integrity of the synapse itself has been compromised, the receptors won't function effectively.

Studies show that an estimated 81 % of Americans studied have tested positive for BPS, and a 2013 study has found that even trace levels of BPS can disrupt cellular functioning (source), potentially leading to many of the same health risks as BPA.

Lack of ideal thyroid hormone function leads to a global decline in cellular functionality in all bodily systems.

«A «deficiency» of polyunsaturated fatty acids leads to altered rates of cellular regeneration and differentiation, a larger brain at birth, improved function of the immune system, decreased inflammation, decreased mortality from endotoxin poisoining, lower susceptibility to lipid peroxidation, increased basal metabolic rate and respiration, increased thyroid function, later puberty and decreases other signs of estrogen dominance.

Low - quality protein intake can lead to cellular stress; low sex drive; poor brain function, eye health and cardiovascular disease.

This initiates the increased production of cellular energy (ATP) that leads to a cascade of beneficial effects, increasing cellular function and health.

Over the long term, excessive discharge of epinephrine and norepinephrine can lead to the suppression of cellular immune functioning; produce hemodynamic changes, such as increased pressure in heart rate; provoke variations in normal heart rhythms; and produce neurochemical imbalances that may contribute to the development of psychiatric disorders.