Sentences with phrase «cellular garbage»
The phrase "cellular garbage" refers to waste or damaged material that accumulates inside cells. It's like trash that the cells cannot get rid of, and it can negatively affect their functioning. Full definition
The brains of HD mice, like HD patients, accumulate clumps of cellular garbage that can be seen using a microscope.
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Individuals with genetic defects on Nrf2, Glutathione, and SOD genes have an even greater need to support such cellular garbage service.
He predicts that the discovery will help researchers develop very specific anti-inflammatory drugs that can subtly tweak the body's immune responses by targeting distinct ubiquitin ligases and similar enzymes involved in cellular garbage disposal.
With age, the barrier sequestering the damaged proteins breaks down, spilling cellular garbage into both cells...
With age, the barrier sequestering the damaged proteins breaks down, spilling cellular garbage into both cells, the team also discovered.
Other BrightFocus - funded research is studying drugs that stimulate the removal of misfolded protein that is in other cellular garbage, from the retinal pigment epithelium in the sublayer of the retina that we were talking about.
«New cellular garbage control pathway with relevance for human neurodegenerative diseases.»
Remarkably, this pathway seems specific for aggregated proteins like huntingtin and appears to be more potent than previously discovered cellular garbage disposal mechanisms.
Because several human neurodegenerative diseases are known to be linked to an accumulation of abnormal protein aggregates, basic science aimed to understand how cells remove cellular garbage is elementary for designing strategies for a potential prevention or cure of such disorders.
Kefeng Lu, a postdoctoral researcher from China, discovered a new class of helper proteins (termed CUET proteins) present both in yeast and humans that recognize cellular garbage earmarked for disposal by an attached label in the form of the ubiquitously existing protein known as «ubiquitin.»
Tricks such as intracellular antioxidant up regulation, DNA repair, increased autophagy (cellular garbage collection), are all enhanced when nature believes this is necessary, including times of hardship such as perceived famine.
This is likely due to the enormous surge in growth hormone that occurs during sleep, along with the fact that your nervous system and brain cleans up cellular garbage when you sleep, allowing you to form memories, learn, and come back more cognitively sharp the next day.
Researchers have discovered a type of channel within cells that is responsible for funneling misfolded proteins and other cellular garbage to the appropriate waste disposal site within the cell.
Once considered containers of cellular garbage, «scientists now know that vesicles also can contain useful matter, including tiny amounts of genetic material and proteins that convey biological messages to other cells,» reports the New York Times.
Looking more closely, the scientists saw that lysosomes, sacs in cells that help break down cellular garbage, had burst.
When they starved the yeast, the scientists found that the cells developed unusually large vacuoles, the cellular garbage dumps that collect materials to be recycled.
Biochemist Shigekazu Nagata of Osaka University Medical School in Japan and his colleagues wondered what would happen if these cellular garbage collectors went on strike.
Importantly, these newly identified helper proteins channel the cellular garbage by a «self - eating» pathway (autophagy) to the lysosome, a compartment of cells dedicated for destruction and recycling.
Bits of misfolded proteins processed by specialty organelles may accumulate in the main compartment of the cell, the cytosol, where they can be tagged for disposal by the cellular garbage service.
It has previously been shown to activate a cellular process known as autophagy, which protects against aging by enabling cells to degrade and discard old, damaged «cellular garbage» before it damages cells.
Mice chronically treated with CTEP had reductions in those garbage piles, and increased signs that a cellular garbage disposal system called autophagy was working.
Think of them as the cellular garbage service that gets rid of the poisons that would otherwise wreak havoc.