Sentences with phrase «cellular machinery in»

GERBER: Another example is high - speed AFM, which biologists use to see the cellular machinery in action.

Like all retroviruses, HIV has very few genes of its own and must take over the host's cellular machinery in order to propagate and spread throughout the body.

Not exact matches

Now, the research team discovered that the disruption of the cellular proteins pICln and Tgs1, two chief players that help assemble the splicing machinery, causes the fruit flies» neuromuscular system to collapse in a similar manner to patients with SMA.

In short, the cellular machinery works less efficiently in aged eggs, but this is not caused by the age of the chromosomeIn short, the cellular machinery works less efficiently in aged eggs, but this is not caused by the age of the chromosomein aged eggs, but this is not caused by the age of the chromosomes.

Although there are several ways to remove RB from the cellular machinery, the group found that complete loss, rather than inactivation, of the RB gene was associated with changes in gene - networks closely linked to aggressive disease.

«If we can find molecules that modulate membralin, or identify its role in the cellular protein disposal machinery known as the endoplasmic reticulum - associated degradation (ERAD) system, this may put the brakes on neurodegeneration.»

Last, the investigation of informational processing and cellular machineries have revealed that genomes of Asgard archaea, which affiliate with eukaryotes in the tree of life (see the figure), encode proteins that they only share with eukaryotes.

Its cellular machinery will execute the program by producing the same protein as the native organism, taking on new qualities, just as in recombinant techniques.

In particular, this region of the gene might serve as a landing place for cellular machinery that binds to the DNA and reads it, Nikolova said.

Viruses come in all shapes, sizes, and degrees of sturdiness, and with all manner of strategies for getting at the cellular machinery they lack.

These proteins can not themselves be used to prevent bleeding episodes, because the cellular machinery found in plants can not package the human clotting factors into the biologically active form.

To be viable, a hybrid's cellular machinery, for example, a protein and its receptor, must fit smoothly, as a peg in a hole.

In the mitochondria of animal are oxidized to run the cellular machinery

Some of these molecules are a complex of proteins called the Polycomb Repressive Complex 2 (PRC2) that is involved in «silencing» genes so that they are not «read» by the cellular machinery that decodes genetic information, effectively keeping the genetic information in the «off» state.

Entomologist Alain Robichon at the Sophia Agrobiotech Institute in Sophia Antipolis, France, and his colleagues suggest that, in aphids, these pigments can absorb energy from the Sun and transfer it to the cellular machinery involved in energy production1.

«When we study the interactions between the host cell and the virus, we get information about both of them and about how cellular machinery is working under viral infection,» says Alessia Ruggieri, a group leader and virologist at University of Heidelberg in Germany and senior researcher on the study.

Their new study points to a biomarker in the cellular machinery that could not only serve as an early warning of colon cancer, but potentially be harnessed to counteract advanced forms of the disease, the second - largest cause of cancer death in the U.S.

Another possibility, Traynor says, is that the repeated nucleotides cause a toxic buildup of messenger RNA, a key player in the cellular machinery for reading out DNA to make protein.

Our team contributes to understand how the cellular machinery, that is similar in all vertebrates, can regenerate a structure in an animal.

These are self - assembling cellular organs that perform myriad metabolic functions, and in a sense, they are molecular factories with many different pieces of machinery.

I'm excited by the prospect of having to solve tough problems by doing very controlled experiments and understanding how the cellular machinery works normally and what goes wrong in disease.

Once the gene was in place, the normal cellular machinery produced it just like any other enzyme.

In fact, they found that TGF - β halts both the transcription of the p53 gene - the process by which cellular machinery reads the DNA code for a gene - and the subsequent process by which the corresponding p53 protein is produced, known as translation.

These CARs contain two fused parts: an antibody that protrudes from the surface of a T - cell to recognise a protein on cancerous B - cells (commonly CD - 19) in the blood and a receptor inside the T - cell that sends messages to cellular machinery.

In research reported this week in the «first release» section of the journal Science, Aseem Ansari, a professor of biochemistry and genomics at UW — Madison, and colleagues showed that their «molecular prosthesis» can help cellular machinery overcome the blockade posed by the repeats in Friedreich's ataxiIn research reported this week in the «first release» section of the journal Science, Aseem Ansari, a professor of biochemistry and genomics at UW — Madison, and colleagues showed that their «molecular prosthesis» can help cellular machinery overcome the blockade posed by the repeats in Friedreich's ataxiin the «first release» section of the journal Science, Aseem Ansari, a professor of biochemistry and genomics at UW — Madison, and colleagues showed that their «molecular prosthesis» can help cellular machinery overcome the blockade posed by the repeats in Friedreich's ataxiin Friedreich's ataxia.

For me this revealed to be a very cool project, since it challenged evolution and I could test hands on how perfect the cellular machinery is in avoiding endangering itself with the incorporation of important epigenetic nucleotides.

Hartl, a biochemist, and Horwich, a geneticist, are pioneers in the realm of cellular protein chemistry whose collaborations helped unravel the molecular machinery that assists with protein folding.

«My favorite is the one we cited in the manuscript: «Viruses are entities whose genomes are elements of nucleic acid that replicate inside living cells using the cellular synthetic machinery and causing the synthesis of specialized elements that can transfer the viral genome to other cells.

Howard Hughes Medical Institute researchers have identified a telltale change in cellular machinery that could help clinicians predict whether prostate cancers are likely to spread or remain...

Although the researchers found no change in the coding region of the gene, they did find that autistic children were much more likely to have inherited a shortened form of the genes promoter — the DNA sequence that serves as the on ramp for the cellular machinery that will express the gene.

We humans have descended from organisms that adapted to living in a prokaryotic world, and we humans retain (conserved in evolutionary terms) in our Eukaraotic mitochondria the cellular machinery to power our cells that we inherited (i.e., Endosymbiosis) from the prokaryotes of deep time on earth.

«In dementia, the cellular machinery for learning and memory is degenerating.

Previously a distinguished professor in the University of Minnesota's Department of Biochemistry, Molecular Biology and Biophysics, Kalodimos» research into the cellular machinery relevant to cancer has led to important insights into how mutated proteins can drive the development and spread of the disease.

My research is framed within the Wellcome Trust consortium on the archaeal origins of eukaryotic cell organization (http://evocyt.com/), which includes a diverse group of researchers studying the evolution of eukaryotic machinery from different points of view — e.g. how do specific cellular systems work in different lineages, and how did that affect the origin of the eukaryotic cell plan?

But just to simplify, it is in these fireworks inside the mitochondria, where the oxygen we breathe may get a hold of an electron we ate that was pumped with energy by plants (thanks to photosynthesis), and transform that oxygen molecule into what's called superoxide, which can damage our delicate cellular machinery — oxidize our cellular machinery.

Large amounts of any PUFA, moreover, will cause the cell to make less of this enzymatic machinery by convincing the cell that it is no longer needed.26 This competition and cellular confusion can be avoided altogether by providing small amounts of preformed arachidonic acid and DHA in the diet.

Depression, associated with compromised integrity of this intestinal barrier, becomes the swirling storm of inflammation, impairment of cellular machinery (i.e. mitochondria), oxidative stress, and inflammation in a carousel - like forward rotation.