Sentences with phrase «cellular machinery with»

Using new technologies for labeling cellular machinery with light - activated fluorescent markers, they could «turn on» just one molecule at a time.

Not exact matches

Finally, the most absurd feature of your scenario is the idea that any extraterrestrial creature would just happen to have, first, DNA as it's basic molecule of biological information storage, second, cellular machinery anywhere remotely similar to what animals on Earth have, and finally, would just happen to be close enough genetically to be able to mix their DNA with the DNA of any terrestrial being, and come out with a viable result.

Now, the research team discovered that the disruption of the cellular proteins pICln and Tgs1, two chief players that help assemble the splicing machinery, causes the fruit flies» neuromuscular system to collapse in a similar manner to patients with SMA.

Although there are several ways to remove RB from the cellular machinery, the group found that complete loss, rather than inactivation, of the RB gene was associated with changes in gene - networks closely linked to aggressive disease.

To date, much of the research on irradiation's effects on the cellular microenvironment has dealt with samples that included cells, obfuscating the irradiation's effect on just the ECM rather than the cell's internal machinery.

Last, the investigation of informational processing and cellular machineries have revealed that genomes of Asgard archaea, which affiliate with eukaryotes in the tree of life (see the figure), encode proteins that they only share with eukaryotes.

This particular active material, originally developed at Brandeis University, borrows elements of cellular machinery, with bundles of rod - like microtubules forming the filaments, kinesin motor proteins acting as the engines, and ATP as the fuel.

Viruses come in all shapes, sizes, and degrees of sturdiness, and with all manner of strategies for getting at the cellular machinery they lack.

The activation was associated with decreased levels of tau, suggesting that the inhibitor works by re-activating the neuronal autophagy machinery to clear cellular buildup of tau.

These are self - assembling cellular organs that perform myriad metabolic functions, and in a sense, they are molecular factories with many different pieces of machinery.

For me this revealed to be a very cool project, since it challenged evolution and I could test hands on how perfect the cellular machinery is in avoiding endangering itself with the incorporation of important epigenetic nucleotides.

Moderna's mRNA Therapeutics ™ platform builds on the discovery that modified mRNA can direct the body's cellular machinery to produce nearly any protein of interest, from native proteins to antibodies and other entirely novel protein constructs with therapeutic activity inside and outside of cells.

Hartl, a biochemist, and Horwich, a geneticist, are pioneers in the realm of cellular protein chemistry whose collaborations helped unravel the molecular machinery that assists with protein folding.

However, these two life - sustaining processes, which often unfold simultaneously on the strands of DNA, pose a spatial quandary: The cellular machinery that replicates DNA and the one that transcribes genes can collide head - on, destabilizing the genome with disastrous consequences.

Certain types of misfolded proteins defy eradication by the cellular protein degradation machinery and accumulate with age, causing cellular toxicity.

With the edits made, the team starts to assemble edited, synthetic DNA sequences into ever larger chunks, which are finally introduced into yeast cells, where cellular machinery finishes building the chromosome.

Stalled transcription complexes don't just lend DNA repair processes a helping hand; they can also end up causing double - strand breaks by interfering with the cellular machinery that replicates DNA.

Instead of snipping out a part of a gene and replacing it with something different, Maselko's cellular machinery leaves the genes as they are, but puts them into overdrive.

But just to simplify, it is in these fireworks inside the mitochondria, where the oxygen we breathe may get a hold of an electron we ate that was pumped with energy by plants (thanks to photosynthesis), and transform that oxygen molecule into what's called superoxide, which can damage our delicate cellular machinery — oxidize our cellular machinery.

Depression, associated with compromised integrity of this intestinal barrier, becomes the swirling storm of inflammation, impairment of cellular machinery (i.e. mitochondria), oxidative stress, and inflammation in a carousel - like forward rotation.