Sentences with phrase «cellular markers of»

The study examined effects of fat - free chocolate milk consumption on kinetic and cellular markers of protein turnover, muscle glycogen, and performance during recovery from endurance exercise.

What's more, the levels of cellular markers of disease — including the levels of amyloid beta and plaques — were noticeably lower in mice with more neuregulin - 1 compared to controls.

While a range of cellular markers of exhaustion, such as PD - 1 and TIM3, have been characterized and are even the target of cancer immunotherapy drugs, the molecular details of how CD8 T cells switch gears were unclear.

Not exact matches

Investigators studied liver tissue from patients with steatohepatitis, who were heavy alcohol drinkers, and from ethanol - fed mice to identify biochemical markers of cellular senescence.

Bruce Buchholz of the Lawrence Livermore National Laboratory used cellular markers for a study in which he concluded that we're more or less stuck with the number of fat cells we have at about age 20.

Findings by Cincinnati Cancer Center researchers show that levels of bisphenol A (BPA) in men's urine could be a marker of prostate cancer and that low levels of BPA exposure can cause cellular changes in both non-malignant and malignant prostate cells.

(The markers include genes and other DNA components, such as parts of the DNA that turn proteins on or off, and cellular components that play a role in regulating genes.)

Normal anatomical structure and the expression of cell class - specific markers does not demonstrate normal cellular function and connectivity.

The ability to isolate pure CSC populations using cellular markers has led to advances in our understanding of the heterogeneity and plasticity of the CSC phenotype.

For example, one could stain for cellular markers and activation markers to infer the activity status of T lymphocytes

To measure how well a person's immune system is functioning, Dr. Maharaj uses a sophisticated blood test to examine innate and adaptive parts of the body's protection system which includes more than 100 cellular markers.

Current explorations into the molecular underpinnings of cell circuitry are leveraging multiple data types including expression profiling and epigenetic analysis leveraging RNA - seq and CHiP - Seq coupled with molecular markers and cellular phenotypes.

Oligonucleotide - labeled antibodies allow integration of cellular protein and transcriptome measurements at a single - cell level, with the number of simultaneously assayed protein markers far surpassing what can be measured by cytometry - based approaches.

To further characterize HPP - 4382, we screened a selection of alternative genes for expression: two markers of endoplasmic - or general cellular stress, HSPA6 and GADD45A, and ICAM1, a target of NF - B.

They were also able to express markers of the three germ layers, suggesting that they re-established pluripotency at the molecular and cellular levels (Fig. 2I).

Other flow cytometry applications include: cellular phenotyping by multiparameter cytofluorimetric analysis, sorting of fluorescence protein - tagged cells, assessing apoptosis and cell cycle status, the identification / isolation of stem and cancer stem cells (e.g., marker positive, side - population, etc.) and the deposition of single cells.

The BCAAem also induces mammalian target of rapamycin (mTOR) activity (another marker of increased cellular oxidative capacity and mitochondrial gene expression) in cultured cardiomyocytes.

Stress resistance has not been assessed however and so the biological relevance of this finding is currently unknown.32 Several IER trials (75 - 85 % ER on restricted days) in overweight / obese populations have reported reductions in various markers of oxidative stress 37, 41, which in one study was accompanied by a complementary increase in the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directions

It is now documented that people with acne tend to have lower levels of cellular antioxidants and higher levels of markers of oxidative damage.

1) A micronutrient sufficiency test such as Genova NutrEval or the SpectraCell test for vitamin, mineral, and essential fatty acid deficiencies, digestive support, antioxidant status, short - term toxic element exposure, and markers of oxidative stress and cellular damage such as lipid peroxides and 8 - hydroxydeguanosine (8 - OHdG).