Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of
cellular materials in and out of a cell's control center — the nucleus — appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.
This interrupts the transport
of cellular materials along axonal microtubules, causing these materials to accumulate at several points along the axon where they may give rise to varicosities.
From an evolutionary perspective, Freeman said SARM and Axed function are likely important in the peripheral nervous system after injury because programmed axon death allows for efficient packaging of damaged
cellular materials for removal by immune cells.
Although other «three - parent» babies were born in the 1990s, they were created using a different technique in which mitochondria and other
cellular material from the eggs of healthy donors were transferred into the eggs of the mothers, which were then fertilized with the fathers» sperm.
Cities might become biological entities, walls hung with curtains of algae that glow at night and sequester carbon, and floors made from
tweaked cellular material that strengthens like bones as we walk on it.
The Poinars were sufficiently convinced of the potential for amber as a remarkable natural preservative to pursue the possibility of finding fossil tissue and
cellular material far older than any previously identified.
That light interacts with light from fluorescent tags
on cellular material and generates a pattern of interference called a moiré fringe.
This research, says Cheung, «presents a general strategy for increasing the performance of highly compliant — that is, «soft» — robots and mechanisms,» by replacing conventional flexible materials with
new cellular materials «that are much lower weight, more tunable, and can be made to dissipate energy at much lower rates» while having equivalent stiffness.
The acquisition of so
much cellular material from its sisters almost certainly helps the egg start a program of growth through which it becomes the largest cell in the mammalian body.
Previous research has shown that many cells, including cancer cells, communicate directly with one another by emitting tiny bubbles of
cellular material called microvesicles.
These white blood cells digest
unwanted cellular material in the body and the organelles they contain help them achieve that goal.
Accordingly, given the use to which
cellular material in particular could conceivably be put in the future, the systematic retention of that material was sufficiently intrusive to disclose interference with the right to respect for private life.
Although blood cells serve multiple roles in the body and have complex interactions with
other cellular materials, most synthetic blood products have aimed to just stick to the bare basics — shuttling oxygen from the lungs to different vital organs and then bringing carbon dioxide back to the lungs to be exhaled.
One of our current research goals is to examine how this largely mysterious accumulation
of cellular material is organized and we hope that a better knowledge of this will help us understand how centrosomes perform their manifold functions in the cell.»
Cork is
a cellular material and when compressed in the neck of a bottle, it provides an effective barrier to th entry of atmospheric oxygen.
The process causes collagen,
the cellular material in ligaments, to contract, tightening the joint.
He says
the cellular material Schweitzer found must be contamination from outside sources.
She and her team created it by dissolving all
the cellular material in a rat heart, leaving behind only the extracellular matrix, a heart - shaped protein scaffolding.
Now, genetic analysis of the cells has cast fresh doubts on the research and found potential evidence of inadvertent or deliberate switching of
cellular material.
When phytoplankton use carbon dioxide to make new cells, a substantial portion of
that cellular material is released into the sea as a buffet of edible molecules collectively called «dissolved organic carbon.»
«In this study, we identified a novel regulatory factor for the Golgi - ER retrograde transport and a new mechanistic connection between the physiological trafficking and the autophagic transportation of
cellular material.»
Funding will be used primarily for research but also to recruit scientists and develop the infrastructure needed to produce
the cellular materials for investigations.
Unlike inanimate matter, cells contain molecular force generators that produce active contractile stresses in
the cellular material.
As molecular force generators produce active contractile stress in
cellular material, physical concepts for inanimate matter need to be extended to capture material properties of cells.