However, the molecular and
cellular mechanisms controlling interactions within the metaorganisms are poorly understood and many key interactions between the associated organisms remain unknown.
Not exact matches
«We are trying to understand the causes of aging by linking the
mechanisms that
control the oxidation of proteins at the
cellular level with the
mechanisms that determine the lifespan of the whole organism,» Apfeld says.
«Autophagy has crystalized as a common central
mechanism of
cellular quality
control in neurodegenerative disease,» says Dikic.
However, the researchers found that a well - known
cellular mechanism — one that
controls how proteins acquire new functions — also plays a major role.
Future studies should elucidate the molecular and
cellular mechanisms by which regional environment
controls phenotypic variations of neuronal types.
«Biochemists uncover structure of
cellular memory
mechanism: Calcium channel
controls thought, movement and metabolism.»
A unique feature of this DREADD system not found in other methods is that it is not limited to the
control of neurons — activity levels of certain enzymes in almost every tissue type can be
controlled to probe
mechanisms of basic
cellular function.
The authors uncover the
cellular and molecular
mechanisms, as well as the gene network regulated by Sox9 during the early steps of skin tumor initiation and demonstrates that Sox9
controls the long term maintenance and expansion of oncogene expressing cells by promoting self - renewing division and inhibiting differentiation.
A University of Rochester team found a way to make chemotherapy more effective, by stopping a
cellular quality -
control mechanism, according to a study published in Nature Communications.
These include, for example, the
mechanisms behind stem - cell development and what happens when normal
cellular growth spirals out of
control, such as in cancer.
Our lab is interested in identifying the
cellular and molecular
mechanisms involved in the organization and maintenance of the synapse with a specific focus on the
control of neurotransmitter receptor expression and localization.
Contributions that use
cellular and molecular approaches to shed light on
mechanisms of physiological
control at higher levels of organization also appear regularly.
Her group is particularly interested in the
cellular and molecular
mechanisms which
control lung epithelial stem cell fate decisions.
Studying coral calcification with antagonists can provide further information and knowledge to better understand the role and function of genes that participate in the
cellular control mechanism, and in the coral organic matrix.
In ongoing research our major aims are to decipher the molecular programs and
cellular mechanisms that
control and limit neuronal regeneration in mammals.
She is interested in the
mechanisms that
control cellular potential in vivo.
Sophie Jarriault is interested in the
mechanisms that
control cellular potential in vivo.
He studies the molecular
mechanisms by which female steroid hormones such as estrogen
control development, differentiation,
cellular proliferation and survival in hormone - responsive tissues and cancers.
Work in our group is aimed to understand the
cellular, molecular and genetic
mechanisms that
control the establishment and maintenance of epithelial cell polarity.
As a
cellular biologist Dr. Pilar Sanchez Gomez has been interested in the molecular
mechanisms that
control adult neural stem cell (NSC) behavior.
The question of how
cellular behavior is
controlled is at the center of stem cell biology, and understanding the
mechanisms of cell fate regulation is key for treating diseases that occur upon dysregulation, such as cancer or diabetes.
Thomas Jessell has defined key
cellular and molecular
mechanisms that
control the development and functional organization of the spinal cord.
Areas of research include biochemical and
cellular mechanisms, muscle contractility and cell motility, the genetic
control of cell growth and differentiation, and tissue damage and regeneration.
This DNA becomes damaged in the course of normal
cellular processes, and certain forms of mitochondrial DNA damage - to the thirteen genes needed for oxidative phosphorylation - produce malfunctioning mitochondria that can overtake their cells, either by replicating more readily or being more resistant to quality
control mechanisms.
Our hypothesis is that the centralized inhibitory
control over the
cellular protein quality
control mechanisms has evolved to prevent their chronic activation which could be detrimental to metazoan growth and reproduction under normal conditions.
Our goal is to identify conserved signaling
mechanisms through which the nervous system may exert its
control over the
cellular protective machinery.
It is not technically correct to say that the blood «will become overly acidic» as many claim, because blood pH, and
cellular pH is one of the most tightly
controlled mechanisms in the body, however there are significant general health effects from having a diet that is too acidic and many of these stem from our need to «buffer» blood and cells that are potentially too acidic (bring them back to normal range.)
Plasma or serum zinc levels are the most commonly used indices for evaluating zinc deficiency, but these levels do not necessarily reflect
cellular zinc status due to tight homeostatic
control mechanisms [8].
In addition, it is possible for a pet to have a strong titer — even a very strong titer like 1:3200 and to be unprotected against a virus because the particular virus is
controlled by
cellular immunity or
mechanisms other than antibodies.