Sentences with phrase «cellular mechanisms for»
Establishing the role of cigarette smoke in progression of cancer will not only produce the necessary evidence for implementing smoking cessation interventions but may also help to identify cellular mechanisms for therapeutic targeting.
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Both species probably use similar cellular mechanisms for forming long - term memory, including the nuclear calcium switch,» Schuster continues.
«We have already demonstrated that these two synapses process different types of information that in turn is likely to comprise the cellular mechanisms for memory encoding and retrieval at these synapses» explains Hardy Hagena.
«Seeing without eyes: Octopus's skin possesses the same cellular mechanism for detecting light as its eyes do.»
As researchers at the Max Planck Institute of Biochemistry report in the current issue of Nature, they have now decoded a new cellular mechanism for the development of aggregates.
Not exact matches
«While rodents are essential for understanding mechanisms at a cellular or molecular level, at a higher cognitive level, the best you could do was a sort of rough analogy.
The sea slug was the model organism for Kreiner's thesis research, which explored how cellular mechanisms mediate simple behaviors and led to a publication in Science.
The more primitive virus, however, carries no repair mechanisms; a new virion (complete virus) acquires lipids for its envelope by literally ripping them off of the cellular membrane as it buds off from the infected cell.
The report, which drew heavily on two Environmental Protection Agency (EPA) workshops held in 1995, also recommends more research on such topics as DNA biomarkers that can gauge an organism's exposure to endocrine disruptors; models for predicting how endocrine disruptors are metabolized; mechanisms of how endocrine disruptors act at a cellular level; and the effects of mixtures.
Information theory analysis of cell signaling reveals mechanisms for reliable cellular responses despite signal variability.
«Alcohol prevents ability to extinguish fearful memories in mice: Insight into cellular mechanisms illuminates biological target for PTSD therapy.»
In addition, it provides a marker for cell fates and insight into the molecular and cellular mechanisms by which FSC progeny diverge into distinct fates.
For example, Perry says, «There is a great deal of interest in people who understand the basic mechanisms of cellular biology, genetics, and proteins.»
«The goal of our work is to understand the cellular mechanisms responsible for beta cell destruction so that we can identify the best targets for beta cell protection,» Costes said.
The cellular mechanisms responsible for the disappearance of a spatial signature are not yet clearly defined, but these findings lead to the formulation of several hypotheses.
But Skalak says Allen intends to fund such established scientists» work in «wholly new» areas: Doudna, for example, will explore a new mechanism to edit cellular function by targeting RNA.
Unlike steroids, lipoxins are a family of specialized pro-resolving mediator, a class of endogenous molecules that is being investigated to determine their capacity to resolve inflammation as well as their cellular and molecular mechanisms for resolution.
The results of the research open new possibilities for understanding the cellular mechanisms responsible for genome instability and for being able to explore new therapeutic approaches.
A previous study by Segev at the laboratory for research of molecular and cellular mechanisms, directed by Prof. Kobi Rosenblum in the Sagol Department of Neurobiology at the University of Haifa, found a connection between a genetic condition known to be a risk factor for sporadic Alzheimer's and premature aging as manifested in ongoing metabolic stress.
There he studied the fundamental cellular and biochemical mechanisms required for immune cell activation and clearance of infections.
This mechanism helps «clean up» cellular debris at the synapse, by engulfing the debris in a membrane and then removing it, for instance.
Researchers pinpoint the cellular receptor MRGRPX2 as the main mechanism for opioid - induced itching.»
I was extremely enthusiastic about the opportunity to immerse myself in a subject in detail, and chose the mechanisms of cellular immunology to study for a PhD.
For instance, this device can help us understand the mechanisms by which various inputs and treatments alter plant growth at the cellular level.
The researchers from the UC Davis Center for Mind and Brain, which studies cognitive brain mechanisms, and Center for Neuroscience, which studies molecular, cellular and system - level brain mechanisms, each brought specific expertise to the collaborative study.
One of the reasons for this is the lack of knowledge on the cellular mechanisms which cause alterations in nerve transmissions and the loss of memory in the initial stages of the disease.
Dr. Maria Iribarne, first author of this study, commented: «The gosh mutant is a good model for understanding the molecular and cellular mechanism of cone cell death and the pathological process of human LCA.
«Our study shows that the ability of malaria parasites to engage red blood cells is driven by an ancient mechanism for cellular attachment,» said lead author Aditya Paul, a postdoctoral researcher at the Harvard Chan School.
«While it is well - established that obesity generates cellular and molecular stress leading to abnormal functioning of many cellular processes, the mechanisms remain incompletely understood,» said senior author Gökhan S. Hotamisligil, chair of the Department of Genetics and Complex Diseases and the Sabri Ülker Center for Nutrient, Genetic, and Metabolic Research.
Despite much study of attention in the brain, the cellular mechanisms responsible for the effects of attention have remained a mystery... until now.
To avoid detrimental outcome for the organism, cells with mutations that generate deviations from normal chromosomal number are eliminated by cellular protection mechanisms.
To begin to explore the cellular mechanisms that might be responsible for this response, histological analysis revealed less severe disruption of spermatogenesis and gene expression studies suggested that an interplay of ATP - binding cassette (ABC) efflux transporters and solute carrier (SLC) influx transporters in the testicular cells might be involved.
What are the molecular and cellular mechanisms by which patients with certain chronic diseases have increased or decreased risks for developing cancer, and can these connections be exploited to develop novel preventive or therapeutic strategies?
These include, for example, the mechanisms behind stem - cell development and what happens when normal cellular growth spirals out of control, such as in cancer.
MDI Biological Laboratory (ME, USA) scientist Aric Rogers has received a grant of US$ 455,000 over two years from the National Institute on Aging, one of the institutes of the National Institutes of Health, for research on the cellular mechanisms governing longevity.
Research programs of Immunopathology Unit aim to dissect the cellular and molecular mechanisms responsible for immunopathological responses of the liver, with emphasis on the responses that occur during infection with hepatitis B virus (HBV).
The team's research shows that the interaction of CRISPR / Cas systems with the cellular mechanisms of their host organisms is stronger than previously suspected, meaning there could be greater potential for the use of such systems.
The Human Biochemical Genetics Section studies selected biochemical defects and other genetic disorders to provide insight into cellular mechanisms and to care for neglected groups of rare disease patients.
Loss of HR accounts for the genomic instability of EOCs and for their cellular hyper - dependence on alternative poly - ADP ribose polymerase (PARP)- mediated DNA repair mechanisms.
She is currently studying the cellular and genetic mechanisms of liver cancer with the hope of identifying new biomarkers and drug targets for this often fatal disease.
BAR HARBOR — The MDI Biological Laboratory has announced that Aric Rogers, Ph.D., has received a grant of $ 455,000 over two years from the National Institute on Aging (NIA), one of the institutes of the National Institutes of Health, for research on the cellular mechanisms governing longevity.
Additional cellular analysis revealed a subset of these bacterial proteins that were secreted into the host cytoplasm independent of the known Salmonella mechanisms for transporting virulence proteins into host cells
The lab focuses on clarifying the mechanisms of brain plasticity, gene expression, and responses of cellular elements to different psychotropic drugs, and have identified several novel brain sites and pathways that constitute attractive targets for new drug development.
A new study implicates a key cellular mechanism as defective in SMA for the first time, providing a new lead for developing future interventions.
The question of how cellular behavior is controlled is at the center of stem cell biology, and understanding the mechanisms of cell fate regulation is key for treating diseases that occur upon dysregulation, such as cancer or diabetes.
She has pioneered the intergration of large - scale genome and transcriptome sequencing data to understand how genetic variation affects gene expression, providing insight to cellular mechanisms underlying genetic risk for disease.
The prize, considered among the most prestigious in the scientific community, recognizes Schreiber for his work in chemical biology and for the use of small molecules as probes to uncover novel cellular mechanisms at the root of human health and disease.
Understanding the underlying mechanisms allows identifying putative sites for pharmacological intervention and opens the prospect of engineering artificial molecular switches derived from the highly efficient systems that have evolved for cellular signal transduction.
Our ultimate goals in this activity include (1) a better understanding of the molecular mechanisms governing cellular processes and especially those involved in certain kinds of diseases such as cancer and (2) the development of computational tools that can be used for diagnostic / prognostic purposes based on genomic data.
Scott Henderson, who has been directing microscopy core facilities for nearly 25 years, loves to talk about how such facilities help scientists explore essential cellular functions and gain a better understanding of the mechanisms associated with disease.