Sentences with phrase «cellular mechanisms underlying»

The cellular mechanisms underlying this bursting behavior have been studied in vitro, using either acute slices of the adult hypothalamus, or organotypic cultures of neonatal hypothalamic tissue.

She continued to develop these models and to investigate the molecular and cellular mechanisms underlying human tumor dormancy as an instructor in Folkman's lab and later as an Assistant Professor at the Center of Cancer Systems Biology at Tufts University School of Medicine, Boston.

Nicotine alters the connections between neurons using a process that is similar to the cellular mechanisms underlying the creation of memory.

Yusuke did his graduate work in Dr Yukiko Gotoh lab at University of Tokyo and joined the Polleux lab in 2013 where he studies the molecular and cellular mechanisms underlying presynaptic capture of mitochondria.

She has pioneered the intergration of large - scale genome and transcriptome sequencing data to understand how genetic variation affects gene expression, providing insight to cellular mechanisms underlying genetic risk for disease.

We are particularly interested in regulatory variation affecting the transcriptome, as well as cellular mechanisms underlying genetic associations to disease.

Dr. Chartoff's Neurobiology of Motivated Behavior Laboratory, founded in 2009, investigates the molecular, biochemical, and cellular mechanisms underlying drug dependence and withdrawal using animal behavioral models with high relevance to the human condition.

Not exact matches

A research team from Wayne State University recently published a paper in the Journal of Clinical Investigation that provides a paradigm shift in the understanding of cellular and molecular mechanisms underlying diabetic peripheral neuropathy (DPN) and wound healing in the treatment of corneal and skin diabetic ulcers.

A research team from iMM Lisboa led by Luís Graça has found a cellular mechanism that underlies the development of autoimmune diseases.

Future work will focus on the underlying mechanisms involved in developmental changes in colouration, including the role of visual feedback and cellular processes.

Yet the molecular and cellular mechanisms that underlie these problems are still only partly understood.

Dr. Monteggia's lab focuses on the molecular and cellular bases of neural plasticity, the fundamental property of nerve cells to alter their communication, as they pertains to neuropsychiatric disorders, as well as understanding the mechanisms underlying antidepressant efficacy.

The mechanisms underlying consciousness could reside at any of a variety of physical levels: molecular, cellular, circuit, pathway, or some organizational level not yet described.

Research at CNIC is aimed at identifying the cellular and molecular mechanisms underlying the origin and evolution of cardiovascular illnesses.

Noise may disrupt the body on the cellular level in a way that increases the risk of common heart disease risk factors, according to a review topic published today in the Journal of the American College of Cardiology that examined the underlying mechanisms that may lead to noise - induced heart disease.

Prof. Nicoll's lab is interested in elucidating the cellular and molecular mechanisms underlying learning and memory in the mammalian brain.

Using these techniques, Dr. Watanabe is studying cellular and molecular mechanisms underlying synaptic transmission and synaptic plasticity.

Molecular mechanism underlying diseases (conformational diseases, cystic kidney disorders, neuromuscular diseases, inflammation, iron - related diseases, disorders of human reproduction, osteoporosis and bone diseases) are being investigated by many groups with robust animal and cellular models and patients» biological samples.

Transgenerational safety of nitrogen - doped graphene quantum dots and the underlying cellular mechanism in Caenorhabditis elegans.

These findings open up the possibility of augmenting cardiac and neuronal regeneration if the underlying cellular and molecular mechanisms can be revealed.

Beyond cellular senescence, we are uncovering additional underlying mechanisms that contribute to age - related diseases including:

The team currently is exploring the cellular and molecular mechanisms underlying ischemic preconditioning using mice in which HIF - 1 activity has been knocked out in specific cell types within the heart.

Understanding the underlying mechanisms allows identifying putative sites for pharmacological intervention and opens the prospect of engineering artificial molecular switches derived from the highly efficient systems that have evolved for cellular signal transduction.

Because double - stranded viral RNA is typically longer than that naturally found in cells, Hur surmised that a mechanism that uses length to distinguish between viral and cellular RNA might underlie the immune system's discriminatory power.

While mouse has been successfully used to study multiple aspects of kidney development, the amphibian pronephros of Xenopus offers a valuable alternative to explore the underlying molecular and cellular mechanisms.

The scope of the journal encompasses all of «traditional» molecular biology (including DNA replication, recombination and repair, gene expression, RNA processing, translation, and protein folding, modification, and degradation) as well as studies of the molecular interactions and mechanisms that underlie basic cellular processes.

The underlying mechanisms accounting for why hGDAsBMP are so much more beneficial in terms of neuroprotection and functional recovery than either hGDAsCNTF or undifferentiated precursor cells when transplanted into spinal cord injured rats remain to be investigated, but it is likely that multiple cellular functions are involved.

Although there is substantial evidence from neuroimaging studies that the brain of a child with autism is undergoing abnormal development, little is known about the underlying cellular, molecular and genetic mechanisms that lead to the onset of autistic symptoms.

Recent advances in high - throughput molecular and cellular profiling tools, particularly genome - wide transcriptomic analysis, offer the potential for unprecedented insights into the mechanisms underlying the acquisition of immunity.

The «Meet Our Scientists» video entitled «Our relative the fly» presents the research performed by Marco Millán on the cellular and molecular mechanisms underlying the regulation of tissue growth during normal development, tissue homeostasis, and tumorigenesis.

These isogenic cell lines can be used not only to understand the cellular consequences of disease mutations, but also to perform high throughput genetic and pharmacological screens to both understand the underlying pathological mechanisms and to develop novel therapeutic agents to prevent or treat such diseases.

Therefore, the identification of cellular and molecular mechanisms underlying neuron - astrocyte communication will help to a better understanding of the mechanisms of brain phsyiology as well as to appropriately identify cellular targets to direct therapeutic approaches for the future treatment of several brain diseases.

9:45 — 10:15 Filippo Mancia (Columbia Uni) The molecular mechanisms underlying cellular uptake of vitamin A

Sancar, the Sarah Graham Kenan Professor of Biochemistry and Biophysics in the UNC School of Medicine, earned the Nobel Prize in Chemistry this year for his work on mapping the cellular mechanisms that underlie DNA repair, which occurs every single minute of the day due to environmental factors.

To understand the mechanism (s) underlying the MELK function in BBC cells, we examined how inducible shRNA - mediated MELK depletion affects various cellular processes.

In conclusion, our study highlights the importance of studying gene — gene interactions in complex diseases and provides insights into the underlying cellular and molecular mechanisms.

Sarcopenia of aging: underlying cellular mechanisms and protection by calorie restriction.

Fortier Laboratory Dr. Lisa Fortier's laboratory investigates the underlying cellular and molecular mechanisms involved in the development of arthritis with the goal of identifying finding new ways to treat and prevention arthritis.