Sentences with phrase «cellular origin»

The data are an invaluable resource for discovering the still - unknown cellular origin of retinoblastoma — the most common eye cancer in children.

We have since sequenced numerous genomes of human, animal, insect or unknown cellular origin.

Although cutaneous melanoma is common and often fatal, the precise cellular origin of this malignant cancer has been under debate for quite some time.

The researchers used single - cell tracking and profiling approaches and live imaging techniques to identify the earliest cellular origin of melanoma and monitor the changes that these cells experience as they first become malignant and then transform into invasive cancer cells.

At that point, identifying suPAR's cellular origins became critical.

Altogether, this study provides important insights into the changes in the mechanisms that lead to tissue repair, and demonstrates that the capacity of the stem cells to regenerate a tissue does not depend on their cellular origin but rather on their proliferation capacity.

In conclusion, this new study identifies the cellular origin of Pik3ca - induced tumours and reveals that oncogenic Pik3ca activates a multipotent genetic program, setting the stage for future intratumoural heterogeneity at the earliest stage of tumor development.

In a study published in Nature, researchers lead by Cédric Blanpain, MD / PhD, WELBIO investigator and Professor at the Université libre de Bruxelles, Belgium, in collaboration with Pr Wayne Phillips, Australia and Pr Christos Sotiriou, Bordet Institute, Belgium, uncovered the cellular origin of PIK3CA - induced breast tumors and demonstrated that the cancer cell of origin controls tumor heterogeneity and is associated with different breast tumors types and clinical prognosis.

Led by Jean - Christophe Marine (VIB - KU Leuven), a team of researchers has tracked down the cellular origin of cutaneous melanoma, the deadliest form of skin cancer.

In this new study published in Nature, Alexandra Van Keymeulen and colleagues used state of the art genetic mouse models to identify the cellular origin of PIK3CA and p53 induced breast tumors.

The unexpected discovery that rhabdomyosarcoma is not really a muscle cancer may offer broader lessons for researchers seeking the cellular origin of cancers.

In the 1970s Varmus and his colleague Michael Bishop discovered the cellular origin of retroviral genes that turn cancerous, launching the modern era of cancer research.

The research highlights the importance of investigating different cell types in normal human tissues to understand the cellular origin of cancer and the factors that may contribute to its development.

«Identifying the cellular origin of fibrosis.»

Harvard Stem Cell Institute scientists at Brigham and Women's Hospital have found the cellular origin of the tissue scarring caused by organ damage associated with diabetes, lung disease, high blood pressure, kidney disease, and other conditions.

Different cell types exhibit characteristic patterns of DNA methylation which enable scientists to draw conclusions about a tumor's cellular origin.

The cellular origin of kidney fibrosis has long puzzled researchers.

Harold Varmus, M.D., shared a Nobel Prize in Physiology or Medicine in 1989 with J. Michael Bishop, M.D. for their discovery of the cellular origin of retroviral oncogenes.

«Tracing the cellular origins of germline formation and regeneration in the annelids.»